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Organic compounds that contain five carboxyl groups; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from pentacarboxylic acids.
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ODN 1585 sodium is a potent inducer of IFN and TNFα production, a strong stimulator of NK (natural killer) function, and enhances CD8+ T-cell function. It has demonstrated efficacy in inducing regression of established melanomas and protecting against malaria in mice. This compound is valuable for research in acute myelogenous leukemia (AML) and malaria, and can also serve as a vaccine adjuvant.
Potent inducer of IFN and TNFα production
Potent stimulator of NK (natural killer) function
Increases CD8+ T-cell function and IFN-γ production
Induces regression of established melanomas in mice
Confers complete protection against malaria in mice
Useful for acute myelogenous leukemia (AML) and malaria research
Serves as a vaccine adjuvant
Stimulates NK cell-mediated lysis of K562 cells in vitro
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ODN 1585 (sodium) is a potent inducer of IFN and TNFα production, and a strong stimulator of NK (natural killer) cell function. It increases CD8+ T-cell function, including IFN-γ production. This product has been shown to induce regression of established melanomas and offer complete protection against malaria in mice. It can be used for acute myelogenous leukemia (AML) and malaria research, and also serves as a vaccine adjuvant.
Potent inducer of IFN and TNFα production
Strong stimulator of natural killer (NK) cell function
Increases CD8+ T-cell function and IFN-γ production
Induces regression of established melanomas
Confers protection against malaria
Applicable for acute myelogenous leukemia (AML) and malaria research
Functions as a vaccine adjuvant
Induces PBMC to produce IFN-α
Stimulates NK cell-mediated lysis of K562 cells
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ODN 1585 sodium is a synthetic CpG-containing oligodeoxynucleotide (sodium salt) used as an immunostimulatory reagent in research. It potently induces interferon and TNFα, enhances NK and CD8+ T-cell responses, and has applications in vaccine adjuvant studies and disease models such as acute myelogenous leukemia and malaria. Supplied as a white to off-white solid; sequence and analytical data are provided by the manufacturer.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More