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Filtered Search Results
eMolecules 16959-62-9 | METHYL INDOLIZINE-2-CARBOXYLATE | AstaTech | MFCD13178636 | 175.187 | C10H9NO2 | 95.000 | COC(=O)c1cc2ccccn2c1 | 0.25g | 448261701
METHYL INDOLIZINE-2-CARBOXYLATE | AstaTech | 16959-62-9 | MFCD13178636 | 175.187 | C10H9NO2 | 95.000 | COC(=O)c1cc2ccccn2c1 | 0.25g | 448261701
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 15788-16-6 | 1H-BENZIMIDAZOLE-5-CARBOXYLICACID | AstaTech | MFCD00011555 | 162.148 | C8H6N2O2 | 97.000 | OC(=O)c1ccc2[nH]cnc2c1 | 25g | 112534104
1H-BENZIMIDAZOLE-5-CARBOXYLICACID | AstaTech | 15788-16-6 | MFCD00011555 | 162.148 | C8H6N2O2 | 97.000 | OC(=O)c1ccc2[nH]cnc2c1 | 25g | 112534104
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Aobchem AOBCHEM
5000923961 ETHYL 4-FORMYLTHIOPHENE-2-CARB
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Medchemexpress LLC BI-1622 | 2681392-19-6 | 99.0% | 508.53 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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BI-1622 is an orally active, potent, and highly selective HER2 (ERBB2) inhibitor, exhibiting an IC50 of 7 nM. It demonstrates more than 25-fold selectivity over EGFR. BI-1622 has shown high antitumor efficacy in vivo within xenograft mouse tumor models using engineered H2170 and PC9 cells, coupled with a favorable agent metabolism and pharmacokinetics profile.
- Orally active.
- Potent and highly selective HER2 (ERBB2) inhibitor (IC50 of 7 nM).
- Exhibits >25-fold selectivity over EGFR.
- High antitumor efficacy in vivo in xenograft mouse tumor models.
- Favorable agent metabolism and pharmacokinetics profile.
- Inhibits proliferation of HER2-dependent cell lines.
- Good permeability and no PgP-mediated efflux liability.
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eMolecules 2-AMINOIMIDAZOLE 1G
5000189694 2-AMINOIMIDAZOLE 1G
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eMolecules 2-AMINOIMIDAZOLE 10G
5000189696 2-AMINOIMIDAZOLE 10G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
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5000428597 MALACHITE GREEN CARB 100MG
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Ambeed AMBEED
5000897093 2-ISOPROPYLTHIAZOLE-5-CAR 50MG
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eMolecules METHYL 4-OXOOXANE-3-CARB 250MG
5000192584 METHYL 4-OXOOXANE-3-CARB 250MG
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eMolecules METHYL 4-OXOOXANE-3-CARBO 50MG
5000192586 METHYL 4-OXOOXANE-3-CARBO 50MG
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Ambeed AMBEED
5000893055 BENZOD123THIADIAZOLE-5-CAR 1GR
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Ambeed AMBEED
5000893843 1-TOSYLPIPERIDINE-4-CARB 250MG
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Ambeed AMBEED
5000890067 R-TETRAHYDROFURAN-3-CARB 250MG
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Ambeed AMBEED
5000895237 4-BENZYLOXYINDOLE-3-CARB 100MG
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eMolecules 39021-62-0 | 1-Methyl-1H-imidazole-5-carbaldehyde | Advanced ChemBlocks | MFCD00030439 | 110.116 | C5H6N2O | 95.000 | Cn1cncc1C=O | 25g | 112239085
1-Methyl-1H-imidazole-5-carbaldehyde | Advanced ChemBlocks | 39021-62-0 | MFCD00030439 | 110.116 | C5H6N2O | 95.000 | Cn1cncc1C=O | 25g | 112239085
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