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A potent, orally available Aurora kinase inhibitor active against Aurora A, B, and C that displays antiproliferative activity in multiple tumor cell lines. The compound is supplied as a powder for research use and has documented solubility and storage recommendations for both powder and solution forms.
Potent inhibition of Aurora A, B, and C with IC50s of 15, 25, and 19 nM.
Orally bioavailable compound showing antiproliferative activity in tumor cell lines.
Supplied as a powder with high purity (≥98% by HPLC).
Molecular weight 551.48 g·mol⁻¹ and formula C26H31BrN8O.
Soluble in DMSO (16.67 mg/mL) and compatible with common vehicle formulations.
Recommended storage: powder at -20°C (3 years) or 4°C (2 years); in solvent at -80°C (2 years).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More