Pyrazoles
![eMolecules 7364-25-2 | 3-Indazolinone | Combi-Blocks | MFCD00005685 | 134.138 | C7H6N2O | 95.000 | O=c1[nH][nH]c2ccccc12 | 5g | 290690624](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2037965.JPG-250.jpg)
eMolecules 7364-25-2 | 3-Indazolinone | Combi-Blocks | MFCD00005685 | 134.138 | C7H6N2O | 95.000 | O=c1[nH][nH]c2ccccc12 | 5g | 290690624
3-Indazolinone | Combi-Blocks | 7364-25-2 | MFCD00005685 | 134.138 | C7H6N2O | 95.000 | O=c1[nH][nH]c2ccccc12 | 5g | 290690624
Medchemexpress LLC NANOG Human His-SU 10ug
NANOG Protein Human (His-SUMO) which functions to maintain the undifferentiated state of pluripotent stem cells
Medchemexpress LLC Allopurinol | 315-30-0 | 99.9% | 100 G
Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. It is primarily used in the research of hyperuricemia and gout. Additionally, Allopurinol has been observed to decrease the expression of HIF-1α and HIF-2α protein, and exhibits anti-depressant, anti-nociception, and anti-leishmanial effects.
- Potent and orally active xanthine oxidase inhibitor
- Used in hyperuricemia and gout research
- Decreases HIF-1α and HIF-2α protein expression
- Exhibits anti-depressant activity
- Shows anti-nociception activity
- Demonstrates anti-leishmanial effects
![eMolecules 27116-93-4 | Methyl 4-amino-1H-pyrazole-5-carboxylate hydrochloride | Combi-Blocks | MFCD08752937 | 177.590 | C5H8ClN3O2 | 95.000 | Cl.COC(=O)c1[nH]ncc1N | 1g | 495744220](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502188339.JPG-250.jpg)
eMolecules 27116-93-4 | Methyl 4-amino-1H-pyrazole-5-carboxylate hydrochloride | Combi-Blocks | MFCD08752937 | 177.590 | C5H8ClN3O2 | 95.000 | Cl.COC(=O)c1[nH]ncc1N | 1g | 495744220
Methyl 4-amino-1H-pyrazole-5-carboxylate hydrochloride | Combi-Blocks | 27116-93-4 | MFCD08752937 | 177.590 | C5H8ClN3O2 | 95.000 | Cl.COC(=O)c1[nH]ncc1N | 1g | 495744220
Medchemexpress LLC Baculoviral IAP repeat-containing protein 5 (survivin) | >95.0% | 100UG
Recombinant full-length human BIRC5 (survivin) with N-terminal 6xHis and SUMO fusion tags, expressed in E. coli and supplied lyophilized for research applications. The protein is intended for activity and cell proliferation assays and includes manufacturer guidance for storage and handling.
- Full-length human isoform-1 sequence.
- N-terminal 6xHis and SUMO fusion tags for purification.
- Expressed in E. coli and purified to >95.0% as determined by reducing SDS-PAGE.
- Lyophilized from PBS, pH 7.4, and supplied as measured mass vials (5 μg, 10 μg, 50 μg, 100 μg).
- Activity demonstrated in A549 cell proliferation assay (ED50 0.022 μg/mL).
- Recommended storage at -20°C; reconstituted material stable at 4°C for 1 week or frozen for long-term storage.
eMolecules 221135-63-3 | 5-BROMO-3,6-DIMETHYLPYRIDIN-2-AMINE | AstaTech | MFCD28101707 | 201.067 | C7H9BrN2 | 95.000 | Cc1cc(Br)c(C)nc1N | 0.25g | 302805953
5-BROMO-3,6-DIMETHYLPYRIDIN-2-AMINE | AstaTech | 221135-63-3 | MFCD28101707 | 201.067 | C7H9BrN2 | 95.000 | Cc1cc(Br)c(C)nc1N | 0.25g | 302805953
eMolecules 632365-54-9 | methyl 3-amino-1H-pyrazole-5-carboxylate | MFCD09991917 | 1g
Pharmablock | methyl 3-amino-1H-pyrazole-5-carboxylate | 1g | 551090783 | PB201304006 | 632365-54-9 | MFCD09991917 | 141.130 | C5H7N3O2
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Medchemexpress LLC Allopurinol (sodium) | 17795-21-0 | 99.9% | 5 MG
Allopurinol sodium is a potent and orally active xanthine oxidase inhibitor. It is extensively used in research for conditions such as hyperuricemia and gout. This compound has demonstrated a decrease in the expression of HIF-1α and HIF-2α protein, and also shows anti-depressant, anti-nociception, and anti-leishmanial activities.
- Potent xanthine oxidase inhibitor
- Orally active
- Used in hyperuricemia and gout research
- Decreases HIF-1α and HIF-2α protein expression
- Exhibits anti-depressant activity
- Shows anti-nociception activity
- Has anti-leishmanial effects
- Reduces angiogenesis traits
- Stable under recommended storage conditions
![eMolecules 1820-80-0 | 3-Aminopyrazole | Oakwood Chemicals | MFCD00005236 | 83.094 | C3H5N3 | 98.000 | Nc1cc[nH]n1 | 25g | 480124403](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000170332.jpg-250.jpg)
eMolecules 1820-80-0 | 3-Aminopyrazole | Oakwood Chemicals | MFCD00005236 | 83.094 | C3H5N3 | 98.000 | Nc1cc[nH]n1 | 25g | 480124403
3-Aminopyrazole | Oakwood Chemicals | 1820-80-0 | MFCD00005236 | 83.094 | C3H5N3 | 98.000 | Nc1cc[nH]n1 | 25g | 480124403
![eMolecules 1820-80-0 | 3-Aminopyrazole | Oakwood Chemicals | MFCD00005236 | 83.094 | C3H5N3 | 98.000 | Nc1cc[nH]n1 | 5g | 480124402](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000170352.jpg-250.jpg)
eMolecules 1820-80-0 | 3-Aminopyrazole | Oakwood Chemicals | MFCD00005236 | 83.094 | C3H5N3 | 98.000 | Nc1cc[nH]n1 | 5g | 480124402
3-Aminopyrazole | Oakwood Chemicals | 1820-80-0 | MFCD00005236 | 83.094 | C3H5N3 | 98.000 | Nc1cc[nH]n1 | 5g | 480124402
![eMolecules 38858-89-8 | 3,5-DINITRO-1H-PYRAZOLE | AstaTech | MFCD06618360 | 158.073 | C3H2N4O4 | 95.000 | [O-][N+](=O)c1cc([nH]n1)[N+]([O-])=O | 1g | 302798341](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502170679.JPG-250.jpg)
eMolecules 38858-89-8 | 3,5-DINITRO-1H-PYRAZOLE | AstaTech | MFCD06618360 | 158.073 | C3H2N4O4 | 95.000 | [O-][N+](=O)c1cc([nH]n1)[N+]([O-])=O | 1g | 302798341
3,5-DINITRO-1H-PYRAZOLE | AstaTech | 38858-89-8 | MFCD06618360 | 158.073 | C3H2N4O4 | 95.000 | [O-][N+](=O)c1cc([nH]n1)[N+]([O-])=O | 1g | 302798341
eMolecules 153436-54-5 | 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline | MFCD00934896 | 1g
Medchem Express | UPF-648 | 5mg | 446266086 | HY-15600 | 213400-34-1 | MFCD25976753 | 259.080 | C11H8Cl2O3
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eMolecules Building Block Tool<|a>
Research Products International Corp Allopurinol 1 KG
Allopurinol inhibits the enzyme xanthine oxidase, which is involved in the production of uric acid. Researchers may use allopurinol to manipulate uric acid levels in experimental settings, allowing them to study the metabolism and physiological effects of uric acid in various tissues and organs.
Allopurinol may be used in studies examining drug interactions or combination therapies. By understanding how allopurinol interacts with other medications or compounds, researchers can optimize treatment strategies and minimize potential adverse effects.
Allopurinol's mechanism of action extends beyond its inhibition of xanthine oxidase. Researchers may utilize allopurinol to probe the downstream effects of xanthine oxidase inhibition, including alterations in oxidative stress, inflammation, and purine metabolism pathways.