Thiazoles
Apexbio Technology LLC Cytochrome c fragment (93-108) 25mg
Cytochrome c fragment 93-108 is a peptide derived from cytochrome c a mitochondrial protein involved in apoptosis It is designed to interact with apoptotic protease activating factor-1 (Apaf-1) thereby promoting the assembly of the Apaf-1/caspase-9 apoptosome complex and regulating the caspase activation pathway Cytochrome c fragment 93-108 exerts its biological activity primarily through activation of the caspase cascade specifically the activation of caspase-9 and subsequent caspase-3 Based on these pharmacological properties cytochrome c fragment 93-108 holds research potential in studies of apoptosis-related signaling networks caspase activation pathways and drug screening targeting apoptosis regulators
Matrix Scientific 2,4-DICHLORO-1,3-THIAZOLE-5G
2,4-Dichloro-1,3-thiazole, 95+%; 5g,C3HCl2NS, MFCD08691358, mw 154.02, [4175-76-2]
Apexbio Technology LLC Aminothiazole 96-50-4 10mM (in 1mL DMSO)
Aminothiazole (96-50-4) is a small-molecule inhibitor targeting thyroid peroxidase It is designed to interfere with thyroid hormone biosynthesis thereby regulating thyroid hormone levels Aminothiazole exerts its biological activity primarily through inhibition of the thyroid peroxidase enzyme In in vitro studies aminothiazole demonstrates inhibitory activity with an IC50 value typically ranging from 1 to 10 M Based on these pharmacological properties aminothiazole holds research potential in the investigation of thyroid hormone regulatory mechanisms and pathologies such as hyperthyroidism as well as in antimicrobial screening assays
Apexbio Technology LLC TH-302 918633-87-1 50mg
TH-302 (CAS 918633-87-1) is a hypoxia-activated prodrug comprising a 2-nitroimidazole moiety linked to a brominated isophosphoramide mustard Under severe hypoxic conditions (approximately 0 1% O ) TH-302 undergoes bioreductive activation releasing the cytotoxic alkylating agent Br-IPM selectively within hypoxic tumor microenvironments In vitro studies demonstrate markedly increased cytotoxicity against tumor cell lines under hypoxia with IC50 values ranging from 0 1 to 0 8 M for H460 Caki-1 SK-MEL-5 DU145 and HCT116 cells while IC50 values exceed 40 M in normoxic conditions In H460 xenograft mouse models TH-302 induces dose-dependent tumor growth inhibition without hematological toxicity and increases H2AX-positive cells indicating DNA damage TH-302 is utilized to investigate tumor hypoxia-targeting therapies and mechanisms of selective cytotoxicity
Sigma Organic Chemistry 2,6-Di-tert-butyl-4-(dimethylaminomethyl)phenol | 250G | 88-27-7 | MFCD00026283 | 0.96
2,6-Di-tert-butyl-4-(dimethylaminomethyl)phenol, 250G
About This Item:
Storage: room temp
EINECS Number: 201-816-1
Selleck Chemical LLC GGTI 298 TFA salt
GGTI 298 is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycle and induce apoptosis
Selleck Chemical LLC GGTI 298 TFA salt
GGTI 298 is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycle and induce apoptosis
Sigma Organic Chemistry 2-Bromothiazole | 5G | 3034-53-5 | MFCD00005316
CAS #: 3034-53-5
MDL #: MFCD00005316
Purity: >98 %
UNSPSC Code: 12352100
Molecular Weight: 164.02
Chemscene ChemScene | 2-Bromothiazole-4-carboxylic acid | 25G | CS-W003188 | 0.98 | 5198-88-9| MFCD04115729 | 208.036
ChemScene | 2-Bromothiazole-4-carboxylic acid | 25G | CS-W003188 | 0.98 | 5198-88-9| MFCD04115729 | 208.036
Sigma Aldrich Fine Chemicals Biosciences 4-Thiazolecarboxylic acid 97% | 3973-08-8 | MFCD00623589 | 5G
4-Thiazolecarboxylic acid 97% | Purity: 97% | Mol Wt: 129.14 | 3973-08-8 | MFCD00623589 | 5G
eMolecules Ambeed / H-Lys(Z)-NH2.HCl / 250mg / 525212107 / A442488 / / 58117-53-6 / MFCD00035520 / 315.800 / C14H22ClN3O3
Ambeed / H-Lys(Z)-NH2.HCl / 250mg / 525212107 / A442488 / / 58117-53-6 / MFCD00035520 / 315.800 / C14H22ClN3O3
eMolecules Ambeed / 1-(24-Dimethylthiazol-5-yl)ethanone / 5g / 552742361 / A547786 / / 38205-60-6 / MFCD00005331 / 155.220 / C7H9NOS
Ambeed / 1-(24-Dimethylthiazol-5-yl)ethanone / 5g / 552742361 / A547786 / / 38205-60-6 / MFCD00005331 / 155.220 / C7H9NOS
Sigma Aldrich Fine Chemicals Biosciences 2 Isobutyl 3 methoxypyrazi1KG
2-Isobutyl-3-methoxypyrazine is the main characteristic flavor/aroma constituent of bell peppers. It is also found in fresh jalapeno peppers and baked potato.
Matrix Scientific METHYL 2-AMINOTHIAZOLE-4-CA-5G
Methyl 2-aminothiazole-4-carboxylate, 95%-5g,C5H6N2O2S, MFCD00622441, mw 158.18,
Cell Signaling Technology Phospho-Met (Tyr1234/1235) (3D7) Rabbit mAb 20 ul
Phospho-Met (Tyr1234/1235) (3D7) Rabbit mAb 20 ul