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Filtered Search Results
Aobchem 1-(2 3-Difluoropyridin-4-yl)propan-1-one | 95% | CAS 3037676-68-6 | C8H7F2NO | 500mg
1-(2 3-Difluoropyridin-4-yl)propan-1-one | 95% | CAS 3037676-68-6 | C8H7F2NO | 500mg
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Aobchem 1-(6-Methoxynaphthalen-2-yl)-2-methylpropan-1-one | 95% | CAS 179930-43-9 | C15H16O2 | 500mg
1-(6-Methoxynaphthalen-2-yl)-2-methylpropan-1-one | 95% | CAS 179930-43-9 | C15H16O2 | 500mg
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Aobchem (7-Isopropoxynaphthalen-2-yl)boronic acid | 95% | C13H15BO3 | 1g
(7-Isopropoxynaphthalen-2-yl)boronic acid | 95% | C13H15BO3 | 1g
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Aobchem N-(2 6-dioxopiperidin-3-yl)-3-nitrobenzamide | 95% | CAS 194712-33-9 | C12H11N3O5 | 500mg
N-(2 6-dioxopiperidin-3-yl)-3-nitrobenzamide | 95% | CAS 194712-33-9 | C12H11N3O5 | 500mg
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Aobchem 4-(4 5-Dimethylthiophen-2-yl)-3 6-dihydro-2H-pyran | 95% | C11H14OS | 1g
4-(4 5-Dimethylthiophen-2-yl)-3 6-dihydro-2H-pyran | 95% | C11H14OS | 1g
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Aobchem Ethanone 2-chloro-1-(2 3 4-trichlorophenyl)- | 95% | CAS 141303-24-4 | C8H4Cl4O | 250mg
Ethanone 2-chloro-1-(2 3 4-trichlorophenyl)- | 95% | CAS 141303-24-4 | C8H4Cl4O | 250mg
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Aobchem 1-(6-Methoxynaphthalen-2-yl)-2-methylpropan-1-ol | 95% | CAS 757230-69-6 | C15H18O2 | 1g
1-(6-Methoxynaphthalen-2-yl)-2-methylpropan-1-ol | 95% | CAS 757230-69-6 | C15H18O2 | 1g
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Aobchem Ethanone 1-(4 5-dimethyl-2-thienyl)- | 95% | CAS 66587-69-7 | C8H10OS | 500mg
Ethanone 1-(4 5-dimethyl-2-thienyl)- | 95% | CAS 66587-69-7 | C8H10OS | 500mg
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Aobchem (1 2-Dihydroacenaphthylen-5-yl)(methyl)sulfane | 95% | CAS 19162-51-7 | C13H12S | 1g
(1 2-Dihydroacenaphthylen-5-yl)(methyl)sulfane | 95% | CAS 19162-51-7 | C13H12S | 1g
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Aobchem 1-(4-Hexylthiophen-2-yl)ethanone | 95% | C12H18OS | 500mg
1-(4-Hexylthiophen-2-yl)ethanone | 95% | C12H18OS | 500mg
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Aobchem 2-Methoxy-5-methyl-3-(methylthio)pyridine | 95% | CAS 2918936-23-7 | C8H11NOS | 500mg
2-Methoxy-5-methyl-3-(methylthio)pyridine | 95% | CAS 2918936-23-7 | C8H11NOS | 500mg
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Aobchem 1-(Benzo[d]thiazol-2-yl)-2 2-difluoropropan-1-one | 95% | C10H7F2NOS | 1g
1-(Benzo[d]thiazol-2-yl)-2 2-difluoropropan-1-one | 95% | C10H7F2NOS | 1g
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Medchemexpress LLC Jh-viii-157-02 | 1639422-97-1 | 98.98% | 465.55 | 25 MG
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JH-VIII-157-02 is a structural analogue of alectinib, functioning as an ALK inhibitor. It exhibits an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells. It also potently inhibits various EML4-ALK mutants and shows selectivity at other kinases.
- Inhibits EML4-ALK G1202R (IC50, 2 nM).
- Potent inhibition of EML4-ALKwt, EAC1156Y, EAF1174L, EAS1206Y (IC50, 2 nM), EAG1269A (IC50, 3 nM), EAL1196M (IC50, 58 nM), EA1151Tins (IC50, 107 nM), and EAL1152R (IC50, 196 nM).
- Selective inhibition of other kinases including IRAK1, CLK4, RET, RET V804L, RET V804M and IRAK 4.
- Inhibits growth in cancer cell lines like H3122 and DFCI76 (L1152R) with EC50s of 5 and 19 nM.
- Good oral bioavailability at 10 mg/kg in mice.
- Penetrates the CNS of mice.
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eMolecules 78269-85-9 | 2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate | ChemScene | MFCD02683467 | 259.333 | C10H17NO5Si | 97.000 | C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O | 25g | 572231924
2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate | ChemScene | 78269-85-9 | MFCD02683467 | 259.333 | C10H17NO5Si | 97.000 | C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O | 25g | 572231924
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Medchemexpress LLC 2-(4-hydroxy-3-methoxyphenyl)-benzothiazole | 36341-25-0 | MFCD00030231 | 99.3% | 257.31 | C14H11NO2S | 10 MG
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YL-109 is a small-molecule antitumor research compound that induces expression of the carboxyl terminus of Hsp70-interacting protein (CHIP) via aryl hydrocarbon receptor signaling. It inhibits breast cancer cell proliferation, motility, and invasiveness in vitro and has shown tumor growth and metastasis suppression in vivo. Intended for research use only.
- Induces CHIP expression through aryl hydrocarbon receptor signaling.
- Inhibits breast cancer cell proliferation, motility, and invasiveness in vitro.
- Demonstrated tumor growth and metastasis suppression in vivo.
- High purity: 99.3%.
- Molecular formula C14H11NO2S and molecular weight 257.31 g/mol.
- Available as a solid and as a 10 mM solution in DMSO for cell-based studies.
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