Thiazoles
Organic heterocyclic compounds that consist of an azole with both sulfur and nitrogen atoms; includes compounds that are derived from thiazoles.
Quantity
- (2)
- (319)
- (26)
- (1)
- (3)
- (19)
- (3)
- (24)
- (6)
- (7)
- (77)
- (3)
- (6)
- (3)
- (84)
- (190)
- (2)
- (2)
- (10)
- (4)
- (1)
- (9)
Molecular Weight (g/mol)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (7)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (3)
- (4)
- (2)
- (6)
- (1)
- (1)
- (3)
- (1)
- (1)
- (4)
- (5)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (4)
- (13)
- (3)
- (3)
- (2)
- (2)
- (4)
- (1)
- (6)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (1)
- (1)
- (4)
- (6)
- (1)
- (4)
- (8)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (1)
- (7)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (9)
- (1)
- (4)
- (1)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (5)
- (4)
- (1)
- (1)
- (2)
- (6)
- (2)
- (2)
- (2)
- (6)
- (1)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (4)
- (1)
- (3)
- (1)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (5)
- (1)
- (7)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (4)
- (1)
- (6)
- (5)
- (1)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (2)
- (1)
- (3)
- (1)
- (3)
- (1)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (4)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (7)
- (3)
- (1)
- (5)
- (2)
- (3)
- (8)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (3)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (9)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (2)
- (1)
- (3)
- (1)
- (4)
- (3)
- (1)
- (1)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (1)
- (3)
- (2)
- (2)
- (4)
- (2)
- (1)
- (2)
- (3)
- (3)
- (6)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (5)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (6)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (3)
- (1)
- (20)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
Percent Purity
- (2)
- (1)
- (6)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (8)
- (7)
- (2)
- (8)
- (1)
- (14)
- (43)
- (30)
- (2)
- (8)
- (23)
- (4)
- (1)
- (4)
- (2)
- (6)
- (2)
- (3)
- (1)
- (1)
- (2)
- (15)
- (1)
- (1)
- (52)
- (10)
- (284)
- (72)
- (1)
- (16)
- (9)
Physical Form
- (3)
- (138)
- (2)
- (10)
- (1)
- (2)
- (33)
- (16)
- (29)
Boiling Point
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
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5,326
Aobchem AOBCHEM
5000910340 2 2 2-TRIFLUORO-1- 4- METHYLTH
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5,327
Ambeed AMBEED
5000888184 13-BISS-4-S-SEC-BUTYL-45 250MG
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5,328
Ambeed AMBEED
5000889256 5-BROMO-NN-DIMETHYLTHIAZ 250MG
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5,329
Aobchem AOBCHEM
5001022198 3-CHLORO-2-METHOXY-4- METHYLTH
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5,330
Aobchem AOBCHEM
5001022500 2- 6-METHOXYNAPHTHALEN-2-YL -1
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5,331
Aobchem AOBCHEM
5001022662 2- 6-METHOXYNAPHTHALEN-2-YL -1
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5,332
Aobchem AOBCHEM
5001022663 2- 6-METHOXYNAPHTHALEN-2-YL -1
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5,333
Aobchem AOBCHEM
5001022664 2- 6-METHOXYNAPHTHALEN-2-YL -1
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5,334
Aobchem AOBCHEM
5001022803 2-FLUORO-3-METHYL-5- METHYLTH
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5,335
Aobchem AOBCHEM
5001022806 1- 2 5-DIFLUOROPYRIDIN-4-YL -2
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5,336
Aobchem AOBCHEM
5001074357 1- 2-BROMO-3 6-DIFLUOROPHENYL
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5,337
Aobchem AOBCHEM
5001074398 1- 4-BROMO-2 3-DIFLUOROPHENYL
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5,338
Medchemexpress LLC Jh-viii-157-02 | 1639422-97-1 | 98.98% | 465.55 | 25 MG
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Small and Specialty Supplier Partner
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JH-VIII-157-02 is a structural analogue of alectinib, functioning as an ALK inhibitor. It exhibits an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells. It also potently inhibits various EML4-ALK mutants and shows selectivity at other kinases.
- Inhibits EML4-ALK G1202R (IC50, 2 nM).
- Potent inhibition of EML4-ALKwt, EAC1156Y, EAF1174L, EAS1206Y (IC50, 2 nM), EAG1269A (IC50, 3 nM), EAL1196M (IC50, 58 nM), EA1151Tins (IC50, 107 nM), and EAL1152R (IC50, 196 nM).
- Selective inhibition of other kinases including IRAK1, CLK4, RET, RET V804L, RET V804M and IRAK 4.
- Inhibits growth in cancer cell lines like H3122 and DFCI76 (L1152R) with EC50s of 5 and 19 nM.
- Good oral bioavailability at 10 mg/kg in mice.
- Penetrates the CNS of mice.
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5,339
(C)CCOC(=O)ON1C(=O)CCC1=O | 25g | 572231924](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502695678.jpg-250.jpg)
eMolecules 78269-85-9 | 2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate | ChemScene | MFCD02683467 | 259.333 | C10H17NO5Si | 97.000 | C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O | 25g | 572231924
2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate | ChemScene | 78269-85-9 | MFCD02683467 | 259.333 | C10H17NO5Si | 97.000 | C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O | 25g | 572231924
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5,340
Medchemexpress LLC 2-(4-hydroxy-3-methoxyphenyl)-benzothiazole | 36341-25-0 | MFCD00030231 | 99.3% | 257.31 | C14H11NO2S | 10 MG
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Small and Specialty Supplier Partner
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YL-109 is a small-molecule antitumor research compound that induces expression of the carboxyl terminus of Hsp70-interacting protein (CHIP) via aryl hydrocarbon receptor signaling. It inhibits breast cancer cell proliferation, motility, and invasiveness in vitro and has shown tumor growth and metastasis suppression in vivo. Intended for research use only.
- Induces CHIP expression through aryl hydrocarbon receptor signaling.
- Inhibits breast cancer cell proliferation, motility, and invasiveness in vitro.
- Demonstrated tumor growth and metastasis suppression in vivo.
- High purity: 99.3%.
- Molecular formula C14H11NO2S and molecular weight 257.31 g/mol.
- Available as a solid and as a 10 mM solution in DMSO for cell-based studies.
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