Thiazoles

Medchemexpress LLC Th-6 | 3031349-25-1 | 95.0% | 429.44 | 1 ML

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TH-6 is a potent HDAC inhibitor with IC50s of 0.115, 0.135, 0.242, 0.138, and 2.120 μM for HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, respectively. It demonstrates anti-tumor activity and inhibits cell migration and invasion, inducing apoptosis and cell cycle arrest at the G2/M phase.

• Inhibits cell migration and invasion
• Induces apoptosis
• Causes cell cycle arrest at the G2/M phase
• Demonstrates anti-tumor activity
• Potent HDAC inhibitor

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Medchemexpress LLC (S,R,S)-AHPC-C10-NHBoc | 2412055-13-9 | 713.97 | 50 MG

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(S,R,S)-AHPC-C10-NHBoc is a synthesized E3 ligase ligand-linker conjugate. It incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC.

• Synthesized E3 ligase ligand-linker conjugate
• Incorporates (S,R,S)-AHPC based VHL ligand
• Used with a linker for BET-targeted PROTAC

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BIOHIPPO AAV-TH-DIO-hM3D(Gq)-mCherry-WPREs

Recombinant adeno associated virus expressing hM3D(Gq) fused to mCherry under the TH promoter with WPRE and hGH polyA elements. The Cre and Dre logic configuration enables expression only after recombination, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.

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eMolecules​ 95037-35-7 | 2-(2,6-DICHLORO-4-PYRIDYL)-2-PROPANOL | AstaTech | MFCD18375241 | 206.070 | C8H9Cl2NO | 97.000 | CC(C)(O)c1cc(Cl)nc(Cl)c1 | 0.25g | 437209719

2-(2,6-DICHLORO-4-PYRIDYL)-2-PROPANOL | AstaTech | 95037-35-7 | MFCD18375241 | 206.070 | C8H9Cl2NO | 97.000 | CC(C)(O)c1cc(Cl)nc(Cl)c1 | 0.25g | 437209719

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BIOHIPPO AAV-TH-NLS-3XFlag-WPRE-hGH-polyA

Recombinant adeno associated virus expressing 3XFlag under the TH promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.

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BIOHIPPO AAV-TH-taCasp3-TEVp-P2A-EYFP-WPRE-pA

Recombinant adeno associated virus expressing taCasp3/TEVp fused to EYFP under the TH promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.

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Medchemexpress LLC N-(Benzotriazol-1-ylmethyl)-N-benzyl-1-phenylmethanamine | 57684-32-9 | MFCD00375674 | 95.0% | 328.42 | 500 MG

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N-(Benzotriazol-1-ylmethyl)-N-benzyl-1-phenylmethanamine is a drug intermediate used for the synthesis of various active compounds. It is for research use only and not intended for human use.

• Used as a drug intermediate
• Applicable for synthesis of various active compounds
• For research use only

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eMolecules​ 72086-72-7 | (S)-4-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid | Oakwood Chemical | MFCD00076931 | 261.274 | C11H19NO6 | 95.000 | COC(=O)[C@H](CCC(O)=O)NC(=O)OC(C)(C)C | 250mg | 537700092

(S)-4-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid | Oakwood Chemical | 72086-72-7 | MFCD00076931 | 261.274 | C11H19NO6 | 95.000 | COC(=O)[C@H](CCC(O)=O)NC(=O)OC(C)(C)C | 250mg | 537700092

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eMolecules​ Synthonix thiazol-5-ylmethyl N-[(1S 2S 4S)-1-benzyl-2-hydroxy-4-[[(2S)-2-[[(2-isopropylthiazol-4-yl)methyl-methyl-carbamoyl]amino]-3-methyl-butanoyl]amino]-5-phenyl-pentyl]carbamate 250mg 649428981 T71978 0 000 155213-67-5 MFCD00927142 720 950 C37H48N6O5S2

Synthonix thiazol-5-ylmethyl N-[(1S 2S 4S)-1-benzyl-2-hydroxy-4-[[(2S)-2-[[(2-isopropylthiazol-4-yl)methyl-methyl-carbamoyl]amino]-3-methyl-butanoyl]amino]-5-phenyl-pentyl]carbamate 250mg 649428981 T71978 0 000 155213-67-5 MFCD00927142 720 950 C37H48N6O5S2

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BIOHIPPO AAV-TH-DIO-hM3D(Gq)-EGFP-WPREs

Recombinant adeno associated virus expressing hM3D(Gq) fused to EGFP under the TH promoter with WPRE and hGH polyA elements. The Cre and Dre logic configuration enables expression only after recombination, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.

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eMolecules​ 2415163-55-0 | [2-(tert-butoxycarbonylamino)-7-fluoro-1,3-benzothiazol-4-yl]boronic acid | Pharmablock312.120 | C12H14BFN2O4S | 97.000 | CC(C)(C)OC(=O)Nc1nc2c(ccc(F)c2s1)B(O)O | 5g | 601587329

[2-(tert-butoxycarbonylamino)-7-fluoro-1,3-benzothiazol-4-yl]boronic acid | Pharmablock | 2415163-55-0312.120 | C12H14BFN2O4S | 97.000 | CC(C)(C)OC(=O)Nc1nc2c(ccc(F)c2s1)B(O)O | 5g | 601587329

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eMolecules​ 2246-44-8 | 2-Methylnaphthalen-1-amine | Ambeed | MFCD00059135 | 157.216 | C11H11N | 95.000 | Cc1ccc2ccccc2c1N | 100g | 601098094

2-Methylnaphthalen-1-amine | Ambeed | 2246-44-8 | MFCD00059135 | 157.216 | C11H11N | 95.000 | Cc1ccc2ccccc2c1N | 100g | 601098094

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eMolecules​ 1979173-93-7 | N-METHYL-N-FMOC-3-(3-PYRIDYL)-L-ALANINE | AstaTech402.450 | C24H22N2O4 | 95.000 | CN([C@@H](Cc1cccnc1)C(O)=O)C(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 716228190

N-METHYL-N-FMOC-3-(3-PYRIDYL)-L-ALANINE | AstaTech | 1979173-93-7402.450 | C24H22N2O4 | 95.000 | CN([C@@H](Cc1cccnc1)C(O)=O)C(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 716228190

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eMolecules​ 89922-82-7 | 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal | Ambeed | MFCD04039464 | 188.342 | C9H20O2Si | 95.000 | CC(C)(C)[Si](C)(C)OCCC=O | 250mg | 527374964

3-[(tert-Butyldimethylsilyl)oxy]-1-propanal | Ambeed | 89922-82-7 | MFCD04039464 | 188.342 | C9H20O2Si | 95.000 | CC(C)(C)[Si](C)(C)OCCC=O | 250mg | 527374964

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Medchemexpress LLC S-methyl-KE-298 | 143584-75-2 | MFCD31382145 | 98.0% | 252.33 g/mol | C13H16O3S | 10 MG

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S-methyl-KE-298 is the active metabolite of KE-298 reported to inhibit matrix metalloproteinase-1 (MMP-1) production in rheumatoid arthritis synovial cells. Supplied as a solid research chemical, it is intended for in vitro studies and characterization and is provided with defined purity and storage conditions.

• Active metabolite of KE-298.
• Inhibits MMP-1 production in rheumatoid arthritis synovial cells.
• High purity (98.0%).
• Solid, white to off-white appearance.
• Molecular formula C13H16O3S; molecular weight 252.33 g/mol.
• Recommended storage conditions for powder and for solutions.

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