Thiazoles
Medchemexpress LLC DOTA-(t-butyl)3-PEG5-azide | 00-00-0 | 99.7% | C40H76N8O12 | 10MG
DOTA-(t-butyl)3-PEG5-azide is a PEG-based bifunctional chelator linker featuring three tert-butyl-protected DOTA ester groups and a PEG5 spacer terminating in an azide. Supplied as a high-purity research material (99.69%, MW 861.08, formula C40H76N8O12), it is designed for use in bioconjugation, PROTAC linker assembly, and preparation of chelator-conjugated probes.
- Tri(tert-butyl) DOTA protected as tert-butyl esters for synthetic stability.
- PEG5 spacer provides flexibility and improves solubility.
- Azide terminal enables copper-catalyzed and strain-promoted click reactions.
- High purity suitable for research-grade bioconjugation workflows.
- Applicable for preparing chelator-conjugated probes and radiolabeling precursors.
eMolecules Diethyl 2-amino-5-methylthiophene-3,4-dicarboxylate | 321736-09-8 | MFCD02615252 | 1g
Combi-Blocks, Inc. | Diethyl 2-amino-5-methylthiophene-3,4-dicarboxylate | 1g | 603134533 | HA-9003 | 95.000 | 321736-09-8 | MFCD02615252 | 257.300 | C11H15NO4S
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Medchemexpress LLC YL-939 | 3023925-68-7 | 99.0% | 426.51 g/mol | C25H26N6O | 10 MG
YL-939 is a small-molecule ferroptosis inhibitor that prevents iron-dependent cell death by modulating the PHB2/ferritin/iron axis. It has been characterized as a non-classical ferroptosis inhibitor with demonstrated protective activity in cellular assays.
- Inhibits ferroptosis via the PHB2/ferritin/iron axis.
- Demonstrated cellular activity in vitro against ferroptotic insults.
- High chemical purity (~99.0%) and defined physical properties.
- Off-white to light-yellow solid, molecular weight 426.51 g/mol.
- CAS number 3023925-68-7 for unambiguous identification.
- Soluble in DMSO (100 mg/mL) and amenable to in vivo formulations.
- Store as powder at -20°C; limited stability in solution.
![eMolecules Ambeed 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal 250mg 527374964 A718284 0 000 89922-82-7 MFCD04039464 188 342 C9H20O2Si](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules Ambeed 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal 250mg 527374964 A718284 0 000 89922-82-7 MFCD04039464 188 342 C9H20O2Si
Ambeed 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal 250mg 527374964 A718284 0 000 89922-82-7 MFCD04039464 188 342 C9H20O2Si
Medchemexpress LLC S-methyl-KE-298 | 143584-75-2 | MFCD43584752 | 98.0% | 252.33 g/mol | C13H16O3S | 50 MG
S-methyl-KE-298 is the S-methylated active metabolite of KE-298 used in research on matrix metalloproteinase (MMP) regulation. It is applied in in vitro studies to evaluate metabolism, protein binding, and effects on MMP-1 and MT1-MMP expression relevant to rheumatoid arthritis synovial cells.
- Active metabolite useful for MMP biology studies.
- Characterized by analytical data including molecular formula C13H16O3S and molecular weight 252.33 g/mol.
- High purity suitable for analytical and in vitro applications.
- Reported high plasma protein binding in preclinical species and human plasma.
- Available in small milligram quantities for research workflows.
eMolecules Ambeed 2 5-Dioxopyrrolidin-1-yl 2 5 8 11 14 17 20 23 26 29 32 35 38 41 44 47-hexadecaoxapentacontan-50-oate 50mg 811906054 A1662119 0 000 2563873-83-4 MFCD13184971 861 973 C38H71NO20
Ambeed 2 5-Dioxopyrrolidin-1-yl 2 5 8 11 14 17 20 23 26 29 32 35 38 41 44 47-hexadecaoxapentacontan-50-oate 50mg 811906054 A1662119 0 000 2563873-83-4 MFCD13184971 861 973 C38H71NO20
BIOHIPPO AAV-TH-eNpHR3.0-EGFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing eNpHR3.0 fused to EGFP under the TH promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
eMolecules 5-Bromo-2-phenylthiazole | 53715-67-6 | MFCD00561163 | 1g
Ambeed | 5-Bromo-2-phenylthiazole | 1g | 601095884 | A423722 | | 53715-67-6 | MFCD00561163 | 240.120 | C9H6BrNS
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BIOHIPPO scAAV-TH-NLS-Cre-WPREs
Recombinant adeno associated virus expressing Cre under the TH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC M-isobutyl ibuprofen | 66622-47-7 | MFCD08275582 | >=98.0% | 206.28 g/mol | C13H18O2 | 5 MG
m-Isobutyl Ibuprofen (Compound IMP-A) is an impurity produced during the synthesis of ibuprofen and is supplied as a research-grade impurity standard for analytical and quality-control applications. The material is intended for laboratory and research use only and should be handled according to the certificate of analysis and institutional safety procedures.
- Reference impurity for analytical and quality-control use.
- Intended for research use only, not for human or veterinary use.
- Available in small milligram pack sizes suitable for method development.
- Molecular formula C13H18O2; molecular weight 206.28 g/mol.
- Storage conditions provided in the certificate of analysis; follow laboratory safety guidance.
Medchemexpress LLC OF-02 | 1883431-67-1 | ≥98.0% | C84H152N4O6 | 25 MG
OF-02 is an ionizable lipid essential for mRNA delivery, serving as a key component of lipid nanoparticles (LNPs). It becomes protonated in acidic endosomal environments, which aids in the escape of mRNA and effective protein expression in target cells. The lipid's pH-responsive membrane fusion properties allow it to complex with mRNA, disrupt endosomal membrane structures, and facilitate mRNA release into the cytoplasm.
- Ionizable lipid for mRNA delivery
- Key component of lipid nanoparticles (LNPs)
- Promotes endosomal escape of mRNA
- Induces protein expression in target cells
- Utilizes pH-responsive membrane fusion properties
- Enables mRNA release into the cytoplasm
- Used in mRNA vaccine development
- Used in gene editing applications
- Used in protein replacement therapy
BIOHIPPO AAV-TH-fDIO-hChR2(H134R)-mCherry-WPRE-hGH-polyA
Recombinant adeno associated virus expressing hChR2(H134R) fused to mCherry under the TH promoter with WPRE and hGH polyA elements. The Cre and Flp logic configuration enables expression only after recombination, providing precise optogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 | C24H16ClN3O2S | 5 MG
A small-molecule inhibitor of DNA polymerase eta (Pol η) supplied for research use. Provided as a solid in milligram quantities for in vitro and preclinical studies, it is suitable for mechanism-of-action experiments and combination cytotoxicity assays.
- High purity: 98.0%.
- Molecular weight 445.92.
- Chemical formula C24H16ClN3O2S.
- Provided in a 5 MG vial suitable for laboratory assays.
- Intended for in vitro pharmacology and mechanism-of-action studies.
Selleck Chemical LLC (R)-Nepicastat HCl S4926-10mg
(R)-Nepicastat HCl (RS-25560-198) the R-enantiomer of Nepicastat HCl is a potent and selective inhibitor with IC50 of 25 1 nM and 18 3 nM for bovine and human dopamine- -hydroxylase with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors
Medchemexpress LLC 2-Hydroxy-4-methylth 10g | 583-91-5 | 150.20 g/mol | C5H10O3S | 10 G
2-Hydroxy-4-(methylthio)butyric acid is an alpha-hydroxy analogue of methionine used as an orally active methionine source and as a research reagent in studies of amino acid metabolism and nutritional supplementation. It is supplied as a liquid and is used in formulation and biological assays where methionine precursors are required.
- Acts as an orally active source of methionine for nutritional studies.
- Useful in biochemical research on amino acid metabolism and feed supplementation.
- Supplied as a liquid, facilitating formulation and dosing experiments.
- Typical purity around ≥88%, suitable for research applications.
- Available in small research quantities for laboratory use.