Thiazoles
Apexbio Technology LLC KN-93 hydrochloride 1956426-56-4 5mg
KN-93 hydrochloride (CAS 1956426-56-4) is a selective inhibitor of Ca2 /calmodulin-dependent protein kinase II (CaMK II) binding competitively at the calmodulin site with a reported Ki of 0 37 M and an IC50 of 370 nM In isolated gastric parietal cells KN-93 suppresses acid secretion stimulated by carbachol and histamine with IC50 values of 0 15 M and 0 3 M respectively and inhibits mucin-stimulated aminopyrine uptake (IC50 0 6 M) Additionally KN-93 shows inhibitory activity against H /K -ATPase and directly blocks voltage-gated potassium (Kv) channels by promoting C-type inactivation KN-93 is widely used to probe CaMK II signaling and its downstream physiological effects in cellular and electrophysiological studies
Apexbio Technology LLC KN-93 hydrochloride 1956426-56-4 25mg
KN-93 hydrochloride (CAS 1956426-56-4) is a selective inhibitor of Ca2 /calmodulin-dependent protein kinase II (CaMK II) binding competitively at the calmodulin site with a reported Ki of 0 37 M and an IC50 of 370 nM In isolated gastric parietal cells KN-93 suppresses acid secretion stimulated by carbachol and histamine with IC50 values of 0 15 M and 0 3 M respectively and inhibits mucin-stimulated aminopyrine uptake (IC50 0 6 M) Additionally KN-93 shows inhibitory activity against H /K -ATPase and directly blocks voltage-gated potassium (Kv) channels by promoting C-type inactivation KN-93 is widely used to probe CaMK II signaling and its downstream physiological effects in cellular and electrophysiological studies
Spectrum Chemical Manufacturing Corporation Famotidine, USP, 98.5-101%, Spectrum™ Chemical
CAS: 76824-35-6 Molecular Formula: C8H15N7O2S3 Molecular Weight (g/mol): 337.44 InChI Key: XUFQPHANEAPEMJ-UHFFFAOYSA-N IUPAC Name: 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide SMILES: NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1