CORTECS HILIC 2.7 μm columns are designed for retaining very polar compounds using hydrophilic-interaction chromatography (HILIC). This orthogonal separation mode to reversed-phase chromatography benefits from acetonitrile-rich mobile phases and an unbonded HILIC stationary phase, offering increased mass spectrometry response and direct injection of organic extracts (e.g., SPE, LLE, PPT).
- Superior resolution and retention of polar analytes.
- Orthogonal selectivity versus C18 columns.
- Increased mass spectrometry response.
- Direct injection for organic extracts.
- Maximizes HPLC/UHPLC efficiency for enhanced resolution.
- Excellent batch-to-batch reproducibility.
- Resistance to bonded phase loss for good column lifetimes.
- Lower operating backpressure without sacrificing efficiency.
- Simple method transfer across HPLC, UHPLC, and UPLC systems.