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HPLC Columns and Cartridges

Pre-packed columns, cartridges, and guard columns for separation of biomolecules and organic/inorganic analytes; includes normal/reversed phase HPLC, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
HPLC Columns (32,237)
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1 – 15 of 30,607 results
1

Thermo Scientific™ ProPac™ WCX-10 HPLC Columns
GSA_VA

Separate proteins and their variants using these weak cation-exchange columns with exceptionally high resolution.

EDGE
Pore Size Nonporous
Particle Size 10 μm
Stationary Phase Carboxylate
Temperature 60°C
Phase Ion Exchange
Column Type Ion Exchange
pH 2 to 12
Quantity Each
Product Line ProPac
2

Thermo Scientific™ Acclaim™ PepMap™ 100 C18 HPLC Columns
GSA_VA

Use for high-resolution tryptic, natural, and synthetic peptide analyses. Its high loading capacity is exceptional for low abundant peptides in complex proteomic samples.

EDGE
Pore Size 100 Å
Stationary Phase C18
Phase Reversed Phase
USP Type L1
3

Thermo Scientific™ DNAPac™ RP Columns

Get high resolution LC and LC-MS separation of oligonucleotides, including double-stranded (ds) DNA/RNA fragments, using these DNAPac reversed phase columns.

EDGE
4

Thermo Scientific™ Hypersil™ MOS-2 C8 HPLC Columns

Use as a general-purpose C8 phase for acidic and neutral analytes, with decrease silanol activity

Pore Size 120 Å
Carbon Load 6.5%
Stationary Phase C8
Temperature 60°C
Phase Reversed Phase
Column Type Reversed Phase
pH 2 to 8
Surface Area 170 m²/g
Max. Pressure 5800 psi (400 bar)
Product Line Hypersil Classical
USP Type L7
5

Thermo Scientific™ Syncronis™ C18 HPLC Columns

Robust separations with highly pure, high surface area silica that is double endcapped Syncronis C18 preparative HPLC columns with inertness toward basic compounds.

Pore Size 100 Å
Particle Size 5 μm
Carbon Load 16%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Packing Material Spherical, Fully Porous, Ultrapure Silica
Column Type Reversed Phase
pH 2 to 9
Surface Area 320 m²/g
USP Type L1
6

Thermo Scientific™ Accucore™ C18 HPLC Columns
GSA_VA

Use this column, with its specially designed solid core, for a broad range of nonpolar analytes across multiple applications.

EDGE
Pore Size 80 Å
Particle Size 2.6 μm
Carbon Load 9%
Stationary Phase C18
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 1 to 11
Surface Area 130 m²/g
Particle Shape Spherical Solid Core
USP Type L1
7

Thermo Scientific™ Hypersil GOLD™ C18 Selectivity HPLC Columns
GSA_VA

Use these endcapped, ultrapure, silica-based columns to generate exceptional peak shape and resolution for HPLC and LC/MS analyses using generic gradients

8

Thermo Scientific™ Acclaim™ Organic Acid HPLC Columns
GSA_VA

Use for separation of hydrophilic, aliphatic, and aromatic organic acids.

Pore Size 120 Å
Carbon Load 17%
Stationary Phase Proprietary
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Column Type Specialty/Application Specific
pH 2 to 8
Green Features Responsibly packaged
Surface Area 300 m²/g
Product Line Acclaim
9

Thermo Scientific™ MAbPac™ Reversed Phase HPLC Columns

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins.

Pore Size 1500 Å
Particle Size 4 μm
Phase Reversed Phase
Max. Pressure 4000 psi (275 bar)
10

Thermo Scientific™ Hypersil GOLD™ Phenyl HPLC Columns
GSA_VA

Use for quick analysis of aromatic analytes, including glucocorticosteroids, estrogens, fat-soluble vitamins, and phospholipids.

Pore Size 175 Å
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 2 to 8
Surface Area 220 m²/g
USP Type L11
11

Thermo Scientific™ Hypersil GOLD™ SAX HPLC Columns

Analyze smaller organic molecules, including nucleotides and organic acids, quickly and efficiently with Thermo Scientific™ Hypersil™ GOLD SAX LC Columns.

Pore Size 175 Å
Carbon Load 2.5%
Stationary Phase Quaternary Amine
Temperature 60°C
Phase Ion Exchange
Column Type Ion Exchange
pH 2 to 8
Surface Area 220 m²/g
USP Type L14
12

Thermo Scientific™ Hypersil™ Silica HPLC Columns

Use the efficient and selective Thermo Scientific™ Hypersil™ Silica LC Columns for normal phase chromatography of nonpolar and moderately polar organic compounds.

Pore Size 120 Å
Stationary Phase Silica
Temperature 60°C
Phase Normal Phase
Column Type Normal Phase
pH 2 to 8
Surface Area 170 m²/g
USP Type L3
13

Thermo Scientific™ Hypersil™ Phenyl HPLC Columns

Use as a general-purpose column with aromatic selectivity.

Pore Size 120 Å
Carbon Load 5%
Temperature 60°C
Phase Reversed Phase
Endcapped No
Column Type Reversed Phase
pH 2 to 8
Surface Area 170 m²/g
Max. Pressure 5800 psi (400 bar)
Product Line Hypersil Classical
USP Type L11
14

Thermo Scientific™ BioBasic™ SCX HPLC Columns

BioBasic SCX LC Columns are optimized for the separation of proteins, peptides and other cationic species.

Pore Size 300 Å
Particle Size 5 μm
Carbon Load 3%
Stationary Phase Sulfonic Acid
Temperature 60°C
Phase Ion Exchange
Endcapped No
Column Type Ion Exchange
pH 2 to 8
Surface Area 100 m²/g
Max. Pressure 5800 psi (400 bar)
Product Line BioBasic
USP Type L52
15

Thermo Scientific™ ProPac™ IMAC-10 HPLC Columns

Resolve target proteins using a single column in a high-resolution gradient run with ProPac IMAC-10 LC Columns.

Pore Size Nonporous
Particle Size 10 μm
Stationary Phase Lysozyne Poly(IDA) Grafts
Temperature 60°C
Phase Affinity Separation
Packing Material Spherical, Nonporous Polymer
Column Type Separation of Metal-Binding Proteins
pH 2 to 12
Max. Pressure 3000 psi (207 bar)