HPLC Columns
Mac-Mod Evosphere RP18-Amide, 100 Å, 1.7 µm, 0.3 x 50 mm Monodisperse Fully Porous Particle HPLC Column
Evosphere UHPLC and HPLC columns are 100 A Monodispersed Fully Porous Silica-based columns designed to combine the benefits of Fully Porous and Core-Shell particle technology into an improved particle design and morphology that brings cutting-edge loading capacity to ultra-high-resolution particle columns. The Monodispersed Particles provide similar efficiency to Core-Shell products when comparing them directly via particle size matching and significantly increase loadability which allows ultra-high resolution analytical separations to scale to preparative separations for isolation work if needed. The bonded phase chemistries are exciting as well to maximize selectivity with novel C12 bonded phase, 2 multi-modal C18/AR, and C18/PFP bonded phases, an extended and stabilized phenyl funtionality in the Diphenyl bonded phase, a polar endcapped AQUA phase, a Phenyl-Hexyl phase, a propyl PFP phase and the RP18-Amide bonded phases which is great for doing bases at low pH.
Waters Corp WATERS CORPORATION HPLC Column, XSelect CSH Phenyl-Hexyl, 130 Å, 3.5 μm, 2.1 mm × 150 mm
XSelect CSH Phenyl-Hexyl columns offer alternative analyte selectivity for method development. They utilize a trifunctionally bonded C6 phenyl-ligand and Charged Surface Hybrid (CSH) technology, ensuring robust performance across HPLC, UPLC, and UHPLC applications.
- Superior performance and comparable backpressure versus core-shell columns.
- Higher loading capacity and particle size scalability than totally porous particle columns.
- Focuses on reversed-phase contacts; avoids secondary Lewis-base interactions.
- Optimizes selectivity for flexible method development, especially with low pH mobile phases.
- Non-end-capped sorbent enhances acidic chemical retention.
- Ultra-low dispersion hardware for superior separation, resilience, and throughput.
- Facilitates smooth UPLC adoption.
- Broad working pH of 1–11.
Mac-Mod Princeton 2-Ethylpyridine 300 Å, 5 µm, 3 x 250 mm SFC Column
Princeton Chromatography Achiral SFC columns are designed and manufactured in the US, well known for innovating novel and robust workhorse phase chemistries, for the analysis of achiral SFC applications. Princeton designs myriad phase chemistries to improve the selectivity and efficiency of SFC analysis. Known for originally innovating the 2-EP phase chemistry, explore what Princeton has to offer. Columns are available from analytical to preparative sizes and are available in a wide range of pore sizes, particle sizes, column ID's and lengths. If you do not see something that you want, please just ask!
Microsolv Technology Corporation HPLC Column, UDC Cholesterol, 4um, 4.6mm ID x 50mm Length, 100A. 1 EA.
This UDC Cholesterol™ Column is made with Cogent TYPE-C™ Silica , and provides unique Selectivity due to different surface chemistry, compared to typical Reversed Phase Columns. This Silica Hydride Phase is modified with an 11 carbon chain that has a cholesterol molecule attached at the terminus. This gives this column the ability to form “slots” and separate some compounds based on shape. Also, due to the direct silicon carbon bonds, this column has no need for end-capping. Use in Reversed Phase, Normal Phase and Aqueous Normal Phase (ANP). Chosen for analyzing steroidal and other hard to retain compounds including some lipids, peptides, proteins & oligonucleotides. Faster Equilibration than Reversed Phase or HILIC Columns Very Hydrophobic Robust Column Lifetimes Temperature and Solvent Changes Selectivity This size column provides good resolution and short run times and is used in High Through-put Screening.
Waters Corp Waters Column, BEH Phenyl, 2.5 um Particle, 130 A Pore
XBridge BEH Phenyl columns offer complementary selectivity to C18 stationary phases, particularly for polyaromatic compounds. This product features the most chemically stable commercially available Phenyl sorbent, providing ultra-low column bleed, long column lifetimes, and excellent peak shape. Packed in ultra-low dispersion hardware, the 2.5 μm eXtended Performance (XP) columns deliver exceptional separation performance, robustness, and throughput for HPLC assays, while also enabling a seamless transition to UPLC adoption.
- Complementary selectivity to C18 stationary phases
- Chemically stable Phenyl sorbent with ultra-low column bleed
- Extended column lifetimes and excellent peak shape
- Packed in ultra-low dispersion hardware
- 2.5 μm XP technology for exceptional separation, robustness, and high throughput in HPLC assays
- Seamless transition to UPLC adoption
Waters Corp Waters Styragel Column, HMW 2, 500 Å, 20 μm, 7.8 mm × 300 mm
Styragel HMW columns are packed with a 20 μm particle and utilize a special 10 μm frit to minimize polymer shearing, making them ideal for use in high-molecular weight applications.
- Separation mode: SEC/GPC
- Particle substrate: Polymer
- pH range: 2 to 12 pH
- Molecular weight range: 100 to 10000
- Particle shape: Spherical
- Particle size: 20 μm
- Endfitting type: Standard
- Pore size: 500 Å
- Format: Column
- Packing solvent: THF
- System: HPLC
- Technique: GPC
- Inner diameter: 7.8 mm
- Length: 300 mm
- Units per package: 1 pk
Waters Corp Waters XBridge Peptide Column, C18, 130Å, 3.5μm, 4.6 mm ID, 250 mm Length
The XBridge BEH130 C18 Peptide Separation Technology (PST) columns are optimized and QC tested for peptide separations. They feature a small-pore (130Å) trifunctionally bonded BEH particle, providing a wide usable pH range, superior low pH stability, and ultra-low column bleed for proteomics, protein characterization, and peptide synthesis. Based on BEH Technology, these columns ensure excellent separation of various peptides.
- Optimized and QC tested for peptide separations.
- Small-pore (130Å) BEH particle offers wide usable pH range and superior low pH stability.
- Delivers excellent peptide separation with narrow, symmetrical peaks.
- Ensures method stability via special peptide map testing.
- Features cutting-edge bonding, end-capping, and particle synthesis.
- cGMP-certified manufacturing; includes Performance Test Chromatogram and Certification of Acceptance.
Waters Corp XBridge Protein BEH C4 Column, 300 Å, 3.5 μm, 4.6 mm × 250 mm
This XBridge Protein BEH C4 Column is designed for protein separation in HPLC systems, offering lower retention compared to traditional C18 phases. It features a Hybrid particle substrate for reduced protein carryover, increased recovery, and improved peak capacity.
- QC tested and optimized for protein separation based on size, hydrophobicity, and isoelectric point.
- Features a spherical particle shape, low silanol activity, and Hybrid BEH particle technology.
- Supports a pH range of 2 to 10 and withstands a maximum pressure of 6000 psi (415 Bar).
- Particle size is 3.5 μm with a 300 Å pore size and 8% carbon load.
- Internal dimensions are 4.6 mm diameter and 250 mm length.
- Surface area is 90; molecular weight range maximum is 150000.
- USP classification: L26.
Microsolv Technology Corporation HPLC Column, IEX SAX, 5um, 2.1mm ID x 150mm Length, 100A. 1 EA.
This Cogent Ion Exchange Column is a Strong Anion Exchanger (SAX has a positively charged surface ) Stationary Phase that has been a premium value and used by HPLC laboratories for many years. It is manufactured with Quaternary Amine functional groups that are always charged. We use only the highest purity silica available, making this column ideal as an Alternate in USP Methods that use the L9 Classification or for acids analysis or purification. With a 5µm Particle, this column works well and produces excellent data for challenging IEX applications that include Anions (negatively charge compounds).
Waters Corp BioResolve SEC mAb Column, 200Å, 2.5 μm, 7.8 x 150 mm
This SEC mAb Column, with an integrated SEC mAb Guard, is designed to support legacy methods for the accurate and reproducible quantitation of monoclonal antibody monomers from high molecular weight aggregates and lower molecular weight fragments. It features 2.5 μm BEH particle technology, is operable up to 60°C, and includes a guard column to protect against mobile phase contaminants, ensuring extended column lifetime.
- Supports legacy methods for monoclonal antibody analysis.
- Utilizes 2.5 μm BEH particle technology for high-resolution separations.
- Tested for accurate quantitation of monoclonal antibody monomers, aggregates, and fragments.
- Includes a guard column for protection against mobile phase contaminants.
- Offers a wide pH range of 2.5 to 8.
- Maintains mechanical stability under high backpressures.
- Designed for HPLC systems with SEC chemistry.
Advanced Materials Technology HALO 1000 C4 2.7 4.6 X
HALO BIOCLASS C4 1000 Å Protein columns made with innovative large pore Fused-Core particle technology provide best in class performance for high resolution separations and better recoveries of large biomolecules such as mAbs, versus smaller pore size columns. HALO 1000 Å columns are optimized for high performance in HPLC, UHPLC, and LCMS large molecule applications delivering excellent reproducibility and column lifetimes.
Waters Corp ACQUITY Premier HSS PFP VanGuard FIT Column, 1.8 µm, 2.1 mm x 50 mm, 1/pk
ACQUITY Premier HSS PFP VanGuard FIT Column, 1.8 µm, 2.1 mm x 50 mm, 1/pk
Sepax Technologies Inc Sepax HPLC Column HP-Silica, 5 µm, 120 Å, 2.1 x 30 mm
HP-Silica phase is made of activated hydroxyl (-OH) functional group with the pore size selection of 120 Å and particle size selection of 1.8, 3, 5, and 10 µm. Carbon loading is 0.0%. HP-Silica is used as the normal phase as well as HILIC phase. HP-Silica phases are suitable for separations of polar and basic organic compounds, such as vitamins, steroids, as well as pharmaceuticals.
Waters Corp Column, Peptide CSH C18, 2.5 μm, 4.6 × 50 mm
Waters CSH130 C18 based particles provide excellent peptide peak shape in FA- or TFA-containing mobile phases and exhibit low dependence on strong ion pairing agents, ideal for LC or LC-MS applications. These 2.5 μm eXtended Performance [XP] columns are packed in ultra-low dispersion hardware, ensuring exceptional separation, robustness, and throughput for HPLC assays and a seamless transition to UPLC.
- C18 chemistry for reversed-phase separation
- Hybrid, spherical particles; 2.5 μm size, 130 Å pore diameter
- pH range of 1 to 11; max pressure 10000 psi (690 Bar)
- Low silanol activity, endcapped; QC tested for peptides
- Dimensions: 4.6 mm ID × 50 mm length; for UHPLC systems
Mac-Mod Princeton SILICA 60 Å, 3 µm, 4.6 x 75 mm SFC Column
Princeton Chromatography Achiral SFC columns are designed and manufactured in the US, well known for innovating novel and robust workhorse phase chemistries, for the analysis of achiral SFC applications. Princeton designs myriad phase chemistries to improve the selectivity and efficiency of SFC analysis. Known for originally innovating the 2-EP phase chemistry, explore what Princeton has to offer. Columns are available from analytical to preparative sizes and are available in a wide range of pore sizes, particle sizes, column ID's and lengths. If you do not see something that you want, please just ask!