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Cayman Chemical ANTIBODY SBP-7455 25mg
A dual inhibitor of ULK1 and ULK2 (IC50s = 13 and 476 nM, respectively, for the recombinant human enzymes in cell-free assays); inhibits increases in autophagic flux and induces apoptosis in serum-deprived MDA-MB-468 breast cancer cells at 10 µM; reduces the viability of MDA-MB-468 cells at 0.19 µM alone or in combination with olaparib
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