Medications
Cayman Chemical ProstaglndIn F2a AChE TrACr
A PROTAC that drives hexokinase 2 degradation induces degradation of hexokinase 2 in 786-O and PANC-1 cells at 20 UM cytotoxic to 786-O 4T1 PANC-1 HGC-27 and MCF-7 cancer cells (IC50s 34.07 5.08 31.53 6.11 and 21.65 UM respectively) reduces ECAR and OCR in 4T1 cells at 20 UM reduces tumor volume and induces intratumoral cytokine accumulation and pyroptosis in a 4T1 murine mammary carcinoma model at 50 mg/kg
Cayman Chemical 6keto ProstaglndIn F1a AChE
An active metabolite of (S)-duloxetine inhibits SERT NET and DAT in lipid membranes (Kis 266 920 and 2814 nM respectively for the human transporters)
Cayman Chemical ProstaglndIn Screeng AChE
A PTH1R agonist selectively induces cAMP production in COS-7 cells expressing human PTH1R (EC50 2.4 UM) over COS-7 cells expressing human PTH2R (EC50 100 UM) induces calcium release from isolated fetal rat long bones at 1 and 3 UM increases lumbar spine and proximal femur BMD lumbar spine bone strength serum levels of osteocalcin and bone formation in the lumbar spine without affecting serum calcium levels in an OVX rat model of osteopenia at 10 mg/kg per day increases serum but not urinary calcium levels in a TPTX rat model of hypothyroidism at 9 mg/kg
Cayman Chemical OphthalmIc AcId 10mg
A glutathione analog and biomarker of hepatic GSH depletion; formed via the GSH synthesis pathway, substituting 2-aminobutyrate for cysteine; plasma and hepatic levels are increased in fasted mice and in a mouse model of acetaminophen-induced hepatotoxicity
Cayman Chemical ProstaglndIn F2a AChE TrACr
A PROTAC that drives hexokinase 2 degradation induces degradation of hexokinase 2 in 786-O and PANC-1 cells at 20 UM cytotoxic to 786-O 4T1 PANC-1 HGC-27 and MCF-7 cancer cells (IC50s 34.07 5.08 31.53 6.11 and 21.65 UM respectively) reduces ECAR and OCR in 4T1 cells at 20 UM reduces tumor volume and induces intratumoral cytokine accumulation and pyroptosis in a 4T1 murine mammary carcinoma model at 50 mg/kg
Hanna Pharmaceutical Supply Co., Inc. PACLITAXEL 10 DROPS/ML 14ML
NC3396077 PACLITAXEL 10 DROPS/ML 14ML