Medications
Med Vet International Vaseline Petrolatum Impregnated Dressing, 3 x 18 Inch, Sterile, 8884414600, Dozen
Nonadherent Clings and conforms to all body contours Petrolatum impregnant remains moist, nontoxic, nonsensitizing and non-irritating Peelable foil packs Sterile 3 x 18 inches
Med Vet International Lubricating Jelly HR 4 oz. Tube Sterile, 201, 12/Box, 6 Boxes
Active ingredients include water, propylene glycol and hydroxypropyl methylcellulose HR lubricating jelly is chlorhexidine free Bacteriostatic HR lubricating jelly is sterile until the packaging seal is broken 4-oz tube
Cayman Chemical ProstaglndIn Screeng AChE
A PTH1R agonist selectively induces cAMP production in COS-7 cells expressing human PTH1R (EC50 2.4 UM) over COS-7 cells expressing human PTH2R (EC50 100 UM) induces calcium release from isolated fetal rat long bones at 1 and 3 UM increases lumbar spine and proximal femur BMD lumbar spine bone strength serum levels of osteocalcin and bone formation in the lumbar spine without affecting serum calcium levels in an OVX rat model of osteopenia at 10 mg/kg per day increases serum but not urinary calcium levels in a TPTX rat model of hypothyroidism at 9 mg/kg
Cayman Chemical PolymyxIn Bsulfate 5g
MPB is a versatile thiol-specific biotinylating reagent It is specific for sulfhydryl groups or reduced disulfide bonds and will not label proteins lacking a free sulfhydryl group at a pH between 6 5 and 7 5 This probe can be used in combination with the appropriate avidin- or streptavidin-conjugated markers (i e fluorescent enzyme-conjugated etc ) MPB can be used to detect protein sulfhydryl groups on dot blots with sensitivities in the femtomole range 14917 MPB can be utilized for cell sorting enzyme immunoassay protein blotting and various cytochemical procedures 14917
Cayman Chemical S-Ibuprofen 1g
A muscarinic M3 receptor antagonist (Ki 0.76 nM) selective for M3 over M1 M2 M4 and M5 mAChRs (Kis 7.08 44.67 45.71 and 9.33 nM respectively) selectively inhibits contractions in isolated guinea pig ileum bladder and trachea (pA2s 9.44 8.66 and 8.7 respectively) over isolated rabbit vas deferens and isolated guinea pig atria (pA2s 7.9 and 7.48 respectively) inhibits micturition pressure (ED50 0.089 mg/kg i.v.) as well as micturition interval and volume in rats
Cayman Chemical PolymyxIn Bsulfate 1g
Cayman s PPARa Y Complete Transcription Factor Assay Kit is a sensitive method for detecting specific transcription factor DNA binding activity in nuclear extracts and whole cell lysates A specific double stranded DNA (dsDNA) sequence containing the PPAR response element is immobilized onto the wells of a 96-well plate PPARs contained in a sample bind specifically to the immobilized PPAR response element and are detected by addition of specific primary antibodies directed against the individual PPAR isoforms A secondary antibody conjugated to HRP is added to provide a sensitive colorimetric readout at 450 nm Cayman s PPARa Y Complete Transcription Factor Assay Kit is designed to investigate all three PPAR isoforms in 12 samples on a single plate
Cayman Chemical -Ibuprofen-d3 10mg
An irreversible dual inhibitor of EGFR and HER2 (IC50s 34 and 33 nM respectively) inhibits proliferation of A431 SK-BR-3 and SW620 cancer cell lines (IC50s 120 2.5 and 511 nM respectively) suppresses EGFR autophosphorylation and phosphorylation of the downstream effectors AKT and ERK in NCI-H1650 and NCI-H1650(G7) cells inhibits tumor growth in BT474 A431 and SUM190 mouse xenograft models (10 mg/kg)
Cayman Chemical 1-hydroxy Ibuprofen 25mg
An inhibitor of bacterial DNA repair potentiates the activity of ciprofloxacin against MRSA inhibits the ciprofloxacin-induced bacterial SOS response in a reporter assay in a concentration-dependent manner
Cayman Chemical AcetamInophen sulfatepotas 1mg
A natural polyphenolic has antioxidant activity that can be cytoprotective inhibits reverse transcriptases from HIV (Ki 0 58 UM) and MLV inhibits CaCCs blocking the initial agonist-stimulated chloride current
Cayman Chemical m-Isobutyl Ibuprofen 25mg
An mPGES-1 inhibitor (IC50 0.2 UM) selective for mPGES-1 over COX-1 COX-2 5-LO and sEH in cell-free assays at 10 UM inhibits IL-1b-induced production of PGE2 in A549 cells and LPS-induced IL-6 and PGE2 production in J774A.1 macrophages at 10 and 1 UM respectively inhibits the formation of 5-LO products including LTB4 and 5-H(p)ETE induced by A23187 alone or with arachidonic acid and A23187 (IC50s 4.9 and 5.2 UM respectively) prevents leukocyte infiltration into the peritoneal fluid in a mouse model of zymosan-induced peritonitis at 10 mg/kg
Cayman Chemical ProstaglndIn F2a AChE TrACr
A PROTAC that drives hexokinase 2 degradation induces degradation of hexokinase 2 in 786-O and PANC-1 cells at 20 UM cytotoxic to 786-O 4T1 PANC-1 HGC-27 and MCF-7 cancer cells (IC50s 34.07 5.08 31.53 6.11 and 21.65 UM respectively) reduces ECAR and OCR in 4T1 cells at 20 UM reduces tumor volume and induces intratumoral cytokine accumulation and pyroptosis in a 4T1 murine mammary carcinoma model at 50 mg/kg
Cayman Chemical Fluprostenol AChE TrACr 500dtn
A 2-opioid receptor inverse agonist (Ki 0.013 nM in CHO-DG44 cells expressing the mouse receptor) selective for 2-opioid receptors over K- and -opioid receptors (Kis 13 and 12 nM in PC12 and COS-7 cells expressing the mouse and rat receptors respectively) induces axonal retraction in primary mouse hippocampal neurons under both normoxic and hypoxic conditions at 1 and 10 UM an activator of TRPM7 induces calcium influx in HEK293 cells expressing mouse TRPM7 (EC50 20.7 UM) reduces self-administration of alcohol or alcohol mixed with saccharin or quinine in alcohol-preferring rats at 6 mg/kg
