ELISA Substrates and Reagents
Revvity Health Sciences Inc AlphaLISA Epigenetics Buffer #1, 100 mL
AlphaLISA Epigenetics Buffer #1, 100 mL
ABclonal Technology ERK1 / ERK2 Rabbit pAb
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
ABclonal Technology Phospho-eIF2α-S51 Rabbit pAb
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2, MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).
ABclonal Technology Phospho-NDRG1-T346 Rabbit pAb
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Genscript Corporation CEACAM-5/CD66eBiotin His
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated
Medchemexpress LLC Alpha-2-HS-glycoprotein (Fetuin-A), mouse, recombinant (HEK293, His tag) | 9014-81-7 | >95.0% | 5UG
Recombinant mouse AHSG (Fetuin-A) protein expressed in HEK293 cells with a C-terminal His tag. AHSG is a phosphorylated serum glycoprotein primarily produced by hepatocytes; this recombinant preparation is supplied for research applications in biochemical and functional studies.
- Expressed in HEK293 cells with C-terminal His tag.
- Phosphorylated glycoprotein derived from mouse AHSG.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Molecular weight 45-71 kDa.
- Available in multiple microgram packaging options.
- Suitable for biochemical assays, antibody validation, and functional studies.
ABclonal Technology Phospho-ERK1-T202 + ERK2-T185 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
AdipoGen TMB (25 g)
Chemical. CAS: 54827-17-7. Formula: C16H20N2. MW: 240.34. 3,3‘,5,5‘-Tetramethylbenzidine (TMB) chromogenic peroxidase sensitive dye. TMB is a noncarcinogenic substitute (Ames test negative) for benzidine suitable as peroxidase substrate for use in ELISA procedures. The substrate produces a soluble end product that is pale blue in color and can be read spectrophotometrically at 370 or 620-650nm. The TMB reaction may be stopped with 2M H2SO4 (resulting in a yellow color), and read at 450nm. A sensitive and specific reagent for the detection of blood, assay of haemoglobin and assay of horseradish peroxidase (HRP).
ABclonal Technology Phospho-NDRG1-S330 Rabbit pAb
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Cell Signaling Technology PathScanR Phospho-HSP27 Ser78 Sandwich ELISA Kit 10 Kit
PathScanR Phospho-HSP27 Ser78 Sandwich ELISA Kit 10 Kit
ABclonal Technology Phospho-ERK1-T202 + ERK2-T185 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Cell Signaling Technology PathScanR Phospho-c-Kit Tyr703 Sandwich ELISA Kit 50 Kit
PathScanR Phospho-c-Kit Tyr703 Sandwich ELISA Kit 50 Kit