ELISA Substrates and Reagents
ABclonal Technology Phospho-PPP1R12A-S668 Rabbit pAb
Myosin phosphatase target subunit 1 (MBS) is a subunit of myosin phosphatase, which regulates the actin-myosin interaction downstream of the GTPase Rho. RhoA, in its active GTP-bound form, interacts with MBS to control myosin light chain (MLC) phosphorylation, affecting smooth muscle contraction and nonmuscle cell function. RhoA activates Rho-kinase, which phosphorylates MBS and inactivates myosin phosphatase. Overexpression or activation of RhoA increases MBS and MLC phosphorylation. This pathway regulates the balance of actin and myosin interaction. Several isoforms of this gene have been identified due to alternative splicing.
Medchemexpress LLC Discoidin domain-containing receptor 2, rat | >95.0% | 5 UG
DDR2 is a recombinant rat-derived discoidin domain receptor 2 protein expressed in HEK293 cells with a C-terminal His tag. It is a receptor tyrosine kinase involved in tissue remodeling and extracellular matrix signaling, supplied for research applications such as biochemical assays, signaling studies, and antibody validation.
- Expressed in HEK293 cells.
- Derived from rat sequence.
- C-terminal His tag for detection and purification.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Available in small research quantities suitable for assay development.
- Suitable for biochemical assays, signaling studies, and antibody validation.
Meso Scale Discovery R-PLEX Human CEACAM-7/CGM2 ASY
The Meso Scale Discovery R-PLEX Human CEACAM-7 Assay is a multiplex immunoassay that measures CEACAM-7 in human serum plasma and cell culture supernatants It uses electrochemiluminescence (ECL) detection for high sensitivity a wide dynamic range and low sample volume This assay quantifies CEACAM-7 a molecule expressed in gastrointestinal tissue and overexpressed in colorectal cancers aiding in the detection and monitoring of colorectal cancer The kit includes a 96-well plate capture and detection antibodies calibrators and controls
Abcam SD 169, ATP-competitive p38alpha MAPK inhibitor, 50MG
MW 160.17 Da, Purity >99%. Potent, selective and ATP-competitive p38α MAPK inhibitor (IC₅₀ values are 3.2 and 122 nM for α and β, respectively). Orally active. Promotes axonal regeneration in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC HY-15928 5g , PNPP CAS:4264-83-9 Purity:98%
Medchemexpress, HY-15928 5g PNPP CAS:4264-83-9 Formula:C6H4NNa2O6P Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Meso Scale Discovery R-PLEX Human GDF-8 ASYQP
The R-PLEX Human GDF-8 Assay is a multiplex immunoassay kit from Meso Scale Diagnostics for measuring GDF-8 (myostatin) in human serum plasma and cell culture supernatant It uses electrochemiluminescence (ECL) detection offering high sensitivity a broad dynamic range and low sample volume requirements Compatible with SECTOR Imager platforms data is analyzed via MSD Discovery Workbench software The kit includes a 96-well plate with capture and detection antibodies plus calibrators and controls for standard curve generation and assay validation
Meso Scale Discovery R-PLEX Human CEACAM-1 ASY
The Meso Scale Discovery R-PLEX Human CEACAM-1 Assay is a multiplex immunoassay panel that allows simultaneous quantitative measurement of CEACAM-1 in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This assay requires 50 L or less sample volume and has a testing time of 3 5 hours The lower limit of detection is 1 15 pg/mL It is available as a kit including a 96-well plate coated with capture antibodies detection antibodies calibrators and controls This assay can aid research on cancer inflammation liver disease and diabetes
AMERICAN RESEARCH PRODUCTS INC MSE SOLUBLE LEPTIN RECEPTOR KT
NC2942467 MSE SOLUBLE LEPTIN RECEPTOR KT
Agilent Technologies Includes 10 each of 3 different vials containing pre-weighed standards with 4 different molecular masses, total 12 molecular masses, nominal Mp 162 - 7,000,000 Da, 3 x 10 vials, 2 mL
EasiVial PS-H, 2 mL Polystyrene calibration kit. Includes 10 each of 3 different vials containing pre-weighed standards with 4 different molecular masses, total 12 molecular masses, nominal Mp 162 - 7,000,000 Da, 3 x 10 vials, 2 mL
ABclonal Technology pJNK1/2/3-T183/Y185/T221/Y223
The protein encoded by this gene is a member of the MAP kinase family MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development This kinase is activated by various cell stimuli and targets specific transcription factors and thus mediates immediate-early gene expression in response to cell stimuli The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis This kinase is also involved in UV radiation induced apoptosis which is thought to be related to cytochrom c-mediated cell death pathway Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation apoptosis and differentiation Several alternatively spliced transcript variants encoding distinct isoforms have been reported [provided by RefSeq Apr 2016]
Meso Scale Discovery R-PLEX Human MPIF-1/CCL23 ASY
The R-PLEX Human MIF-1 (CCL23) Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures the chemokine Macrophage Migration Inhibitory Factor (MIF-1 or CCL23) in human serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity up to 5-logs of dynamic range and low sample volume requirements The kit includes a 96-well plate pre-coated with capture antibody detection antibody read buffer calibrator and sample diluent The assay can detect MIF-1 concentrations as low as 3 5 pg/mL with an upper limit of 100 000 pg/mL