Protein Molecular Weight Markers
ABclonal Technology Bmi1 Rabbit pAb
This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.
ABclonal Technology GNA14 Rabbit pAb
This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.
ABclonal Technology IL17RA Rabbit pAb
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
ABclonal Technology NOP14 Rabbit pAb
This gene encodes a protein that plays a role in pre-18s rRNA processing and small ribosomal subunit assembly. The encoded protein may be involved in the regulation of pancreatic cancer cell proliferation and migration. Alternative splicing results in multiple transcript variants.
ABclonal Technology METTL21C Rabbit pAb
Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in protein methylation. Located in nucleus. Part of protein-containing complex.
ABclonal Technology SLAMF6 Rabbit pAb
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
ABclonal Technology TSC1 Rabbit pAb
This gene is a tumor suppressor gene that encodes the growth inhibitory protein hamartin. The encoded protein interacts with and stabilizes the GTPase activating protein tuberin. This hamartin-tuberin complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. This protein also functions as a co-chaperone for Hsp90 that inhibits its ATPase activity. This protein functions as a facilitator of Hsp90-mediated folding of kinase and non-kinase clients, including TSC2 and thereby preventing their ubiquitination and proteasomal degradation. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis.
ABclonal Technology DEFB132 Rabbit pAb
Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. This protein binds spermatozoa and has antimicrobial activity against E. coli. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13.
ABclonal Technology USP22 Rabbit mAb
Enables enzyme binding activity, nuclear receptor coactivator activity, and thiol-dependent deubiquitinase. Contributes to H4 histone acetyltransferase activity. Involved in positive regulation of mitotic cell cycle, positive regulation of transcription, DNA-templated, and protein modification by small protein conjugation or removal. Part of SAGA complex.
ABclonal Technology RTN4RL1 Rabbit pAb
Enables signaling receptor activity. Predicted to be involved in negative regulation of axon regeneration. Located in cell surface. Is anchored component of plasma membrane.
S2 Media 15x100mm Chameleon™ COLOREX™ Campylobacter, 10/pack
Chameleon™ COLOREX™ Campylobacter is a selective and differential, chromogenic culture medium used for the qualitative direct detection and presumptive identification of thermotolerant Campylobacter. Test specimens include rectal swabs and stools. Chameleon™ COLOREX™ Campylobacter can also be used in the detection of Campylobacter in the analyses of food products for human consumption, animal feed, and in environmental samples in accordance with the ISO 10272-1. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI and ISO performance criteria.• Chameleon™ COLOREX™ Campylobacter should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
S2 Media 15x100mm Chameleon™ COLOREX™ STEC, 10/pack
Chameleon™ COLOREX™ STEC is a selective and differential, chromogenic culture medium used for the qualitative direct detection and presumptive identification of Shiga-Toxin Producing Escherichia coli (STEC). Test specimens include rectal swab and stools. It can also be used in the detection of STEC in the analyses of food products for human consumption, animal feed and in environmental samples. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies. Media can also be used in the detection of STEC in the analyses of food products for human consumption, animal feed and in environmental samples. • Product meets CLSI performance criteria.• Chameleon™ COLOREX™ STEC should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
S2 Media 15x100mm Chameleon™ COLOREX™ MRSA (RUO), 10/pack
Chameleon™ COLOREX™ MRSA (RUO) is a selective and differential, chromogenic medium used for the qualitative direct detection of Methicillin Resistant Staphylococcus aureus (MRSA). Test specimens include anterior nares or perineal swabs, positive blood cultures and swabs from skin, soft tissue, and wounds. For Research Use Only (RUO). Not for use in diagnostic procedures unless Laboratory Developed Test (LDT) validation with the product has been completed. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ MRSA should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
S2 Media 15x100mm Chameleon™ COLOREX™ Orientation, 10/pack
Chameleon™ COLOREX™ Orientation is a non-selective, differential, chromogenic culture medium used for the qualitative direct detection and presumptive identification of uropathogens associated with urinary tract infections (UTI). Test specimens include urine. Concomitant cultures should be performed to recover organisms for further microbiological testing or epidemiological typing. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ Orientation should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
S2 Media 15x100mm Chameleon™ COLOREX™ ESBL (RUO), 10/pack
Chameleon™ COLOREX™ ESBL (RUO) is a selective and differential, chromogenic culture medium used for the qualitative direct detection of gastrointestinal colonization with Extended-Spectrum-Beta-Lactamase (ESBL) resistant Enterobacteria. Test specimens include rectal swabs and stools. For Research Use Only (RUO). Not for use in diagnostic procedures unless Laboratory Developed Test (LDT) validation with the product has been completed. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ ESBL should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.