Protein Molecular Weight Markers
ABclonal Technology MCCC2 Rabbit pAb
This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Sigma Aldrich Fine Chemicals Biosciences Gel filtration Markers Kit
Gel filtration markers kit contains five vials of proteins and 1 vial of blue dextran for calibration.
ABclonal Technology ZCCHC10 Rabbit pAb
Predicted to enable nucleic acid binding activity and zinc ion binding activity.
ABclonal Technology CNAP1 Rabbit mAb
Enables histone binding activity. Involved in mitotic chromosome condensation. Located in condensed chromosome, cytosol, and nucleoplasm. Part of condensin complex. Colocalizes with cytoplasm and nuclear chromosome. Implicated in primary autosomal recessive microcephaly.
ABclonal Technology HEXIM2 Rabbit pAb
This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants.
ABclonal Technology DLAT Rabbit mAb
This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.
ABclonal Technology GABARAPL2 Rabbit pAb
Enables ubiquitin protein ligase binding activity. Involved in negative regulation of proteasomal protein catabolic process and protein localization to endoplasmic reticulum. Located in Golgi membrane and autophagosome membrane.
Cayman Chemical CItrulntd Myeln BasIc Pr 500uL
An orally bioavailable broad-spectrum triazole antifungal agent completely inhibits growth of T. rubrum M. audouini M. canis and T. verrucosum as well as some C. albicans and A. fumigatus strains and other fungi (100 g/ml) bacteriostatic against E. coli P. aeruginosa S. aureus and S. pyogenes (100 g/ml) eliminates vaginal C. albicans candidiasis infection in 97 of rats (1 topical) eliminates vaginal C. albicans candidiasis infection in 50 of rats (10 mg/kg oral) decreases synthesis of 14a-desmethyl sterols and increases synthesis of methylated sterols in C. albicans (IC50 3 nM)
ABclonal Technology PPM1E Rabbit mAb
This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene.
Sigma Aldrich Fine Chemicals Biosciences fluorescent IEf-Marker pI
filtered through a 0.45 mum membrane filter
Biotium Primary Antibody Human IgG Fc N2508.HFC CF680 1/EA
Anti-Human IgG (Fc) rVHH (N2508 HFC) is a recombinant Alpaca VHH antibody that recognizes the Fc domain of human IgG and is validated for IF and flow Far-red/near-IR STORM-compatible CF680 dye has Ex/Em at 681/698 nm Unit size 500 uL at 0 1 mg/mL
ABclonal Technology PBR/TSPO Rabbit pAb
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported, one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.
ABclonal Technology DCAF7 Rabbit mAb
This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants.