Complex Aldehydes
Medchemexpress LLC YBX1 protein, human (His) | >90.0% | 20UG
Recombinant full-length human YBX1 protein with a C-terminal 6xHis tag, expressed in Escherichia coli and supplied lyophilized from PBS with 6% trehalose. Intended for research use in biochemical assays, binding studies, and detection workflows.
- Full-length human protein with C-terminal His tag.
- Expressed in Escherichia coli for bacterial expression systems.
- Lyophilized formulation for long-term storage.
- Purity greater than 90% by reducing SDS-PAGE.
- Predicted molecular mass 42.7 kDa; SDS-PAGE shows ~60 kDa band.
- Stable when stored at -20°C; reconstitute and aliquot for use.
Apexbio Technology LLC 6-Thio-dG 789-61-7 10mg
6-Thio-2 -deoxyguanosine (6-Thio-dG CAS 789-61-7) is a nucleoside analogue that functions as a telomerase-mediated telomere targeting agent In telomerase-positive cancer cells 6-Thio-dG is incorporated into telomeric DNA inducing rapid telomere dysfunction independent of direct telomerase inhibition which leads to growth arrest and cell death In vitro cancer cell lines exhibit IC50 values ranging from 0 7 to 2 9 M indicating high sensitivity to the compound Normal cells with telomerase-silent status show minimal morphological effects upon 6-Thio-dG exposure In vivo 6-Thio-dG administration inhibits tumor growth and reduces proliferation markers in xenograft models The compound is valuable for investigating telomere biology and as a tool to evaluate telomerase-dependent therapeutic strategies in cancer research
Apexbio Technology LLC 6-Thio-dG 789-61-7 25mg
6-Thio-2 -deoxyguanosine (6-Thio-dG CAS 789-61-7) is a nucleoside analogue that functions as a telomerase-mediated telomere targeting agent In telomerase-positive cancer cells 6-Thio-dG is incorporated into telomeric DNA inducing rapid telomere dysfunction independent of direct telomerase inhibition which leads to growth arrest and cell death In vitro cancer cell lines exhibit IC50 values ranging from 0 7 to 2 9 M indicating high sensitivity to the compound Normal cells with telomerase-silent status show minimal morphological effects upon 6-Thio-dG exposure In vivo 6-Thio-dG administration inhibits tumor growth and reduces proliferation markers in xenograft models The compound is valuable for investigating telomere biology and as a tool to evaluate telomerase-dependent therapeutic strategies in cancer research
Apexbio Technology LLC 6-Thio-dG 789-61-7 50mg
6-Thio-2 -deoxyguanosine (6-Thio-dG CAS 789-61-7) is a nucleoside analogue that functions as a telomerase-mediated telomere targeting agent In telomerase-positive cancer cells 6-Thio-dG is incorporated into telomeric DNA inducing rapid telomere dysfunction independent of direct telomerase inhibition which leads to growth arrest and cell death In vitro cancer cell lines exhibit IC50 values ranging from 0 7 to 2 9 M indicating high sensitivity to the compound Normal cells with telomerase-silent status show minimal morphological effects upon 6-Thio-dG exposure In vivo 6-Thio-dG administration inhibits tumor growth and reduces proliferation markers in xenograft models The compound is valuable for investigating telomere biology and as a tool to evaluate telomerase-dependent therapeutic strategies in cancer research