Laboratory and Industry Automation
Apexbio Technology LLC SGI-1776 free base 1025065-69-3 5mg
SGI-1776 free base (CAS 1025065-69-3) is an ATP-competitive inhibitor targeting Pim kinases a serine/threonine protein kinase family implicated in regulating cellular survival pathways It selectively inhibits all three isoforms Pim-1 Pim-2 and Pim-3 leading to decreased phosphorylation of downstream substrates involved in cell cycle regulation and apoptosis such as p21Cip1/WAF1 and Bad Cellular studies indicate that SGI-1776 induces G1 cell cycle arrest promotes apoptosis and overcomes chemoresistance mediated by multidrug resistance protein 1 (MDR1) in taxane-resistant prostate cancer cells
Nanotemper Technologies Inc 10X DIANTHUS MICROWELL PLATE
- Microwell plate type for biophysical assays.
- Features 384 wells for high-throughput screening.
- Plates are barcoded for easy sample tracking.
- Compatible with Dianthus system for TRIC measurements.
- Constructed from black/black polystyrene for light protection.
- Clear bottom for optical detection from below.
- Working volume range of 18-25 µL to suit various assays.
- Optimal working volume of 20 µL for enhanced performance.
- Coated with a special polymer to minimize protein adsorption.
- Packs include a rack of 10 plates for convenient use.
Medchemexpress LLC cGMP-HTL | 99.7% | 844.27 g/mol | C31H51ClN7O14PS | 5 MG
cGMP-HTL (cGMP-HaloTag-ligand) is a cGMP-containing HaloTag ligand developed as an autophagy inducer. It promotes K63-linked ubiquitination of mitochondria and is supplied as a high-purity solid with recommended solvent solubility and storage conditions for research use.
- Induces autophagy by increasing K63-linked ubiquitination of mitochondria.
- Contains an HT-ligand, a linker, and a Cys-S-cGMP autophagy tag.
- High purity (99.7%) suitable for biochemical and cell-based studies.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store sealed, away from moisture and light; in solution store at -80°C up to 6 months or -20°C up to 1 month.
Kuhner Shaker Inc TRAY FOR MICROTITER PLATES F
- Designed for microtiter and deepwell plates
- Features a spring mechanism for individual plate handling
- Suitable for various laboratory applications
- Ensures efficient and reproducible results
- Robust design accommodates multiple plate types
- Compatible with Kuhner shaker systems
- Dimensions: 800 mm x 420 mm
- Capacity: 1-24 microtiter plates
- Plates compatible: Deepwell or microtiter plates
- Loading mechanism: Springs for easy loading/unloading