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PDK1-IN-RS2 is a substrate-selective small-molecule inhibitor of 3-phosphoinositide-dependent protein kinase-1 (PDK1). It mimics the peptide docking motif (PIFtide) and is used in biochemical and cellular studies to probe PDK1-dependent signaling within the PI3K/Akt/mTOR pathway.
Substrate-selective PDK1 inhibitor (Kd ≈ 9 μM).
Useful for studying PI3K/Akt/mTOR pathway and downstream kinase activation.
Chemical formula C15H9ClN2O2S3; molecular weight 380.89 g/mol.
Available as a 5 mg solid suitable for assay preparation and compound screening.
High purity (reported 98.49%) for reliable biochemical results.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
cGMP-HTL (cGMP-HaloTag-ligand) is a cGMP-containing HaloTag ligand developed as an autophagy inducer. It promotes K63-linked ubiquitination of mitochondria and is supplied as a high-purity solid with recommended solvent solubility and storage conditions for research use.
Induces autophagy by increasing K63-linked ubiquitination of mitochondria.
Contains an HT-ligand, a linker, and a Cys-S-cGMP autophagy tag.
High purity (99.7%) suitable for biochemical and cell-based studies.
Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
Store sealed, away from moisture and light; in solution store at -80°C up to 6 months or -20°C up to 1 month.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More