PDK1-IN-RS2 is a substrate-selective small-molecule inhibitor of 3-phosphoinositide-dependent protein kinase-1 (PDK1). It mimics the peptide docking motif (PIFtide) and is used in biochemical and cellular studies to probe PDK1-dependent signaling within the PI3K/Akt/mTOR pathway.
- Substrate-selective PDK1 inhibitor (Kd ≈ 9 μM).
- Useful for studying PI3K/Akt/mTOR pathway and downstream kinase activation.
- Chemical formula C15H9ClN2O2S3; molecular weight 380.89 g/mol.
- Available as a 5 mg solid suitable for assay preparation and compound screening.
- High purity (reported 98.49%) for reliable biochemical results.