Oligonucleotides
Biotium CD43 (T-Cell Marker) (rSPN/1094), CF647 conjugate, 0.1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low ab
BIOHIPPO AAV-TH-Cre-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre under the TH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-GFAP-eNpHR3.0-EYFP-WPREs
Recombinant adeno associated virus expressing eNpHR3.0 fused to EYFP under the GFAP promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC Transferrin R2 Mous 10ug | 10ug
The transferrin R2 protein is a key player in iron-independent cellular uptake of transferrin-bound iron underscoring its role in delicate iron metabolism Among other things it may have crucial effects on liver cell function and red blood cell differentiation Transferrin R2 Protein Mouse (HEK293 mFc) is the recombinant mouse-derived Transferrin R2 protein expressed by HEK293 with N-mFc labeled tag
ABclonal Technology AFTMag Quick Gel DNA Extraction Kit (Prepackaged)
This kit uses magnetic bead-based technology for nucleic acid purification. It utilizes functional groups on magnetic beads to enrich nucleic acids from agarose gel onto the bead surface.The beads are then washed to remove impurities, and then separate magnetic beads with magnetic separation device, so as to quickly separate and purify DNA from samples. The whole process does not require the use of phenol, chloroform and β-merphytoethanol,, safe and non-toxic, and the use of paramagnetic magnetic beads, suitable for high-throughput automated extraction.
American Radiolabeled Chemicals Inc CHOL PALM 3H 50UC
Cholecalciferol palmitate-palmitate-9,10-3H 50uCi in toluene, 1 mCi/ml, 50-60 Ci/mmol, (Vitamin D3 palmitate), M.W. 622.56, Shipped in Dry Ice, Exclusive
BIOHIPPO AAV-RAM-d2tTA:TRE-Cre-EGFP-WPRE-bGH-polyA
Recombinant adeno associated virus expressing d2TTA Cre fused to EGFP under the RAM TRE promoter with WPRE and hGH polyA elements. The Tet responsive configuration enables doxycycline controlled expression, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Cayman Chemical 17R 18S-EpETE 100ug
An EPA metabolite and activator of KCa1.1/BK channels; increases the potassium current amplitude by 15-fold in isolated rat cerebral artery VSMCs at 50 nM; has negative chronotropic effects in NRCMs (EC50 = ~1-2 nM) and prevents calcium-induced increases in NRCM spontaneous beating
TARGETMOL CHEMICALS INC STING ACTIVATOR COMPOUND 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation. purity: 98%
Biotium pS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein)(rTFF1/1091), Biotin conjugate, 0.1mg/mL
Recognizes a polypeptide of 6. 5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelih
BIOHIPPO BAX-sh-GFP-Puro
BAX-sh-GFP-Puro shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated human/mouse BAX shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse BCL2 associated X apoptosis regulator (BAX) The shRNA has been validated to meet or exceed 70% BAX knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
ABclonal Technology GAPDH Rabbit pAb
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase family, known as a moonlighting protein due to its multiple distinct functions. It catalyzes an important step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate with NAD and inorganic phosphate. The protein also has uracil DNA glycosylase activity in the nucleus and antimicrobial properties against E. coli, P. aeruginosa, and C. albicans. Additionally, similar proteins in mice have been linked to regulating mRNA stability, nitrosylating nuclear proteins, and acting as a transferrin receptor on macrophage surfaces. Many pseudogenes related to this gene exist in the human genome. Alternative splicing generates multiple transcript variants.