Oligonucleotides
Biotium CD43(SPN/839), CF740 conjugate, 0.1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low ab
Cayman Chemical Flos Sopoa matuus Toxutn 5g
A flavonoid with diverse biological activities; reduces D-galactose-induced increases in renal MDA levels and decreases in renal Cu/Zn SOD, catalase, and GPX activities in mice at 150 mg/kg per day, as well as attenuates D-galactose-induced increases in renal levels of NF-κB p65, iNOS, COX-2, and EP2 levels; reduces blood glucose levels, plasma triglyceride levels, heart rate, and blood pressure in a rat model of STZ-induced type 2 diabetes at 150 mg/kg per day; prevents the loss of dopaminergic neurons in the SNC and reduces apomorphine-induced contralateral rotations in a rat model of Parkinson’s disease induced by 6-OHDA at 150 mg/kg per day
Biotium pS2(TFF1/1091), CF740 conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased
Biotium pS2(TFF1/1091), 0.2mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased
Biosurface Technologies Corp 6-Channel PET Drip Flow Biofilm Reactor, Low-Shear Laboratory Biofilm Growth Device, BioSurface Technologies Corporation.
"The Model DFR 110 Drip Flow Biofilm Reactor® consists of four (4) or six (6) parallel test channels, each capable of holding one (1) standard glass microscope slide-sized coupon, or a length of catheter or stint (after custom modification upon request). Growth media is provided by dripping over the coupon or catheter surface. Biofilm growth conditions provide low shear, and short residence time (2 minutes). Catheter and stent studies can also utilize the alternate end media port to provide flow within the catheter or stent. Media flows via gravity to provide a very low shear condition.The Drip Flow Biofilm Reactor® is ideal for microsensor monitoring, general biofilm studies, biofilm cryosectioning samples, high biomass production, dental and medical material evaluations, and indwelling medical device evaluations.ASTM E2647 is a standardized method developed for the Drip Flow Biofilm Reactor®.
Abcam Bendamustine hydrochloride, DNA alkylating agent, 50MG
MW 394.7 Da, Purity >99%. DNA alkylating agent. Causes DNA intrastrand and interstrand cross-links. Induces apoptotic gene expression. Anticancer, apoptotic agent in vivo.
The product is subject to the following: Abcam Restricted Use Statement
BIOHIPPO AAV-nEF1a-fDIO-mCherry-T2A-TK-WPRE-hGH-polyA
Recombinant adeno associated virus expressing TK fused to mCherry under the nEF1a promoter with WPRE and hGH polyA elements. The Cre and Flp logic configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-mTH-NLS-Cre-EGFP-WPREs
Recombinant adeno associated virus expressing Cre fused to BFP under the mTH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Biotium SOX9 / SRY-box 9(SOX9/2287R), CF594 conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
BIOHIPPO AAV-VGAT1-WGA-CRE-P2A-EGFP-WPREs
Recombinant adeno associated virus expressing WGA-Cre fused to EGFP under the VGAT1 promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Meridian Life Science Liquid Stable Flex DNA qPCR, 800UL
Liquid Stable Flex DNA qPCR Mix is a combination of the latest advances in buffer chemistry and PCR enhancers and stabilizers, together with an antibody-mediated hot start polymerase and containing dUTP. Liquid Stable Flex DNA qPCR Mix has been designed to be stable for at least 12 months at ambient temperature. In addition, it has been optimized for highly reproducible and accurate assay, delivering exceptional performance in multiplex assays, even under fast thermal cycling conditions. Liquid Stable Flex DNA qPCR Mix formulation is compatible to applications where reduction of false positives from cross-over contamination is critical.
Meridian Life Science Liquid Stable Ready DNA qPCR, 4ML
Liquid Stable Ready DNA qPCR Mix is a combination of the latest advances in buffer chemistry and PCR enhancers and stabilizers, together with an antibody-mediated hot start polymerase and containing dUTP. Liquid Stable Ready DNA qPCR Mix has been designed to enable pre-assembled qPCR assay (MDX364 + assay oligonucleotides) be stable for at least 12 months at ambient temperature. In addition, it has been optimized for highly reproducible and accurate assay, delivering exceptional performance in multiplex assays, even under fast thermal cycling conditions. Liquid Stable Ready DNA qPCR Mix formulation is compatible to applications where reduction of false positives from cross-over contamination is critical.
Meridian Life Science Air-Dryable DNA LAMP, 50ML
Air-Dryable DNA LAMP Mix is a glycerol-free mix for isothermal applications such as Loop-Mediated Isothermal Amplification (LAMP). It contains Bst-DNA Polymerase (exo-), reaction buffer, dNTP and provided with air-dryable excipients. This is a robust master mix for loop-mediated isothermal amplification (LAMP) reactions, has been designed for amplification of DNA targets. In order to produce dried, ambient temperature stable LAMP assays, assay specific primers are added to Air-Dryable DNA LAMP for subsequent air-drying.
BIOHIPPO AAV-mscRE4-minBGpromoter-Cre-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre under the mscRE4 promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Biotium DNA Ligase 1(1A9), CF488A conjugate, 0.1mg/mL
DNA Ligase I maintains the major DNA Ligase activity in proliferating cells by joining Okazaki fragments during lagging strand DNA replication. Human DNA Ligase I also has an essential role in DNA repair pathways, where it catalyzes the formation of phosphodiester bonds between adjacent 5' phosphoryl and 3' hydroxy termini at single breaks in duplex DNA molecules. In addition, DNA Ligase I plays a role in sealing nicks during excision repair. Similar to other DNA ligases, DNA Ligase I is built around a common catalytic core. Increased levels of DNA Ligase I are found in human tumors, as compared to benign tissues, as well as in peripheral blood lymphocytes. DNA Ligase I activity is altered in the chromosomal breakage deficit Bloom's syndrome (BS). Individuals with BS either have decreased levels of abnormally thermolabile DNA Ligase I or possess a dimeric form of this enzyme. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. C