Oligonucleotides
Medchemexpress LLC ABCA1 protein, human recombinant | >90.0% | 10UG
Recombinant human ABCA1 protein produced in HEK293 cells with N-StrepII, C-FLAG, and N-8xHis affinity tags. Designed for research applications such as studies of lipid transport, cholesterol efflux, and HDL biogenesis. Characterized by reducing SDS-PAGE and supplied in microgram-scale quantities.
- Expressed in HEK293 cells for human-like post-translational modifications.
- Multiple affinity tags to facilitate purification and detection.
- Purity greater than 90% as determined by reducing SDS-PAGE.
- Molecular weight approximately 258.4 kDa.
- Supplied in small microgram quantities suitable for analytical and functional assays.
ABclonal Technology NCKAP1 Rabbit pAb
Contributes to small GTPase binding activity. Involved in Rac protein signal transduction, positive regulation of Arp2/3 complex-mediated actin nucleation, and positive regulation of lamellipodium assembly. Located in extracellular exosome and focal adhesion. Part of SCAR complex.
Cayman Chemical Precelys 2 mL Metal Tube 1ea
A stainless steel tube used in conjunction with the Precellys Evolution Touch (Item No. 38707)
AUTOMATION TRAINER GLH QC KIT 96 MICROPLATES
Quality Simplified: Automation Trainer’s GLH QC Kit allows users to characterize the error limits of volume transfers and define calibration recommendations for automated liquid handling platforms, manual pipettors, and microplate readers.The vision behind the GLH QC Kit was to provide users with a simplified, accurate, and cost-effective quality control solution.Test your automated liquid handlers, multi-channel pipettes, readers, labware, and more. Develop unique liquid classes and Optimize Assays.- Single-Dye Absorbance-Based Method- Characterizes error limits of volume transfers (1 nL to 10 mL)- Compatible with any manual or automated liquid handling instrument (up to 1536-channels)- Test the photometric accuracy, precision, and linearity of most readers with the GLH Validation Reference Plate- Low Diluent-Dispense sensitivity with GLH Verification MicroplatesĉĉĉĉĉĉĉĉĉĉGLH QC Kit - 96-Well Verification Microplatesĉĉĉĉĉĉĉĉĉĉĉĉĉĉĉĉĉĉĉĉĉĉĉ16-May-25 08:59:37:000 PMĉ
Biotium SOX9 / SRY-box 9(SOX9/2287R), CF488A conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
Cayman Chemical N4TosylLargInIn methyl e 5g
A synthetic substrate of serine proteases, including thrombin, trypsin, chymotrypsin, and kallikreins; also binds to and inhibits anaphase-promoting complex, a ubiquitin ligase, in Xenopus egg extract
Biotium SOX9 / SRY-box 9 (PCRP-SOX9-1A2), Biotin conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are n
ABclonal Technology Phospho-PTEN-S380/T382/383 Rabbit pAb
This gene encodes a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase that functions as a tumor suppressor, frequently mutated in various cancers. The protein contains a tensin-like domain and a catalytic domain similar to dual specificity protein tyrosine phosphatases, but preferentially dephosphorylates phosphoinositide substrates. It regulates AKT/PKB signaling by decreasing phosphatidylinositol-3,4,5-trisphosphate levels. A non-canonical initiation site produces a longer isoform, potentially involved in regulating mitochondrial energy metabolism. A pseudogene exists on chromosome 9. Alternative splicing and multiple start codons generate different isoforms of the protein.
Genscript Corporation MSLN/Mesothelin296-580 hFc C
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally
New England Biolabs, Inc. WarmStart RTx Reverse Transcriptase (Glycerol-free) - 2000 units
WarmStart RTx Reverse Transcriptase (Glycerol-free) is formulated without glycerol to support lyophilization, incorporation into microfluidic devices, and enable quick adoption into automation workflows. WarmStart RTx Reverse Transcriptase is a unique in silico designed RNA-directed DNA polymerase coupled with a reversibly-bound aptamer that inhibits RTx activity below 40°C. This enzyme can synthesize a complementary DNA strand initiating from a primer using RNA (cDNA synthesis) or single-stranded DNA as a template. RTx is a robust enzyme for RNA detection in amplification reactions and is particularly well suited for use in LAMP (loop-mediated isothermal amplification). The WarmStart property enables high throughput applications, room temperature setup, and increases the consistency and specificity of amplification reactions. RTx contains intact RNase H activity.
Biotium PDZ and LIM Domain 1(CPTC-PDLIM1-1), CF740 conjugate, 0.1mg/mL
CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (-actinin-1, thereby facilitating the association of Clik1 with actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88% sequence similarity with its rat counterpart, suggesting a conserved function between species. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue
BIOHIPPO AAV-VGAT1-DO-tdTomato-DIO-EGFP-WPREs
Recombinant adeno associated virus expressing EGFP tdTomato EGFP under the VGAT1 promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Biotium pS2(TFF1/1091), CF488A conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased