Oligonucleotides
Sigma Aldrich Fine Chemicals Biosciences X tremeGENETM HP DNA Trans
X-tremeGENE HP DNA Transfection Reagent is a multi-component reagent that forms a complex with DNA then transports the complex into animal or insect cells.
BIOHIPPO AAV-RAM-d2tTA-TRE-hM3D(Gq)-EYFP-WPRE-bGH-polyA
Recombinant adeno associated virus expressing d2TTA hM3D(Gq) fused to EYFP under the RAM TRE promoter with WPRE and hGH polyA elements. The Tet responsive configuration enables doxycycline controlled expression, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO PAX2-TAG-Puro LV
PAX2-TAG-Puro is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a puromycin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Medchemexpress LLC Cellular retinoic acid-binding protein 1, human recombinant | >95.0% | 50 UG
Recombinant human cellular retinoic acid-binding protein 1 (CRABP1), expressed in E. coli and supplied tag-free as a lyophilized powder. Supplied as a 50 μg unit, the protein is >95% pure, ~14 kDa, full length (M1-E137), formulated in 50 mM Tris-HCl, 300 mM NaCl, pH 8.0, 10% glycerol, with endotoxin <1 EU/μg. Store at -20°C; reconstitute to at least 100 μg/mL in ddH2O and follow laboratory handling procedures.
- Recombinant human protein expressed in E. coli.
- Tag free preparation suitable for functional assays.
- Purity greater than 95% by reducing SDS-PAGE.
- Approximate molecular weight of 14 kDa.
- Lyophilized powder formulation for long-term storage.
- Low endotoxin level (<1 EU/μg) for sensitive applications.
- Reconstitution recommended to at least 100 μg/mL in ddH2O.
- Stable at 4°C for 1 week after reconstitution or at -20°C for long-term storage with carrier protein.
Cayman Chemical THUNDRTotal GAPDH TRFRET 480
Sandwich TR-FRET immunoassay for semi-quantitative detection of Total GAPDH in cell lysates
ABclonal Technology Non-pAct -CateninS33/S37/T41
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs) AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete Finally this protein binds to the product of the APC gene which is mutated in adenomatous polyposis of the colon Mutations in this gene are a cause of colorectal cancer (CRC) pilomatrixoma (PTR) medulloblastoma (MDB) and ovarian cancer Alternative splicing results in multiple transcript variants
BIOHIPPO AAV-fSST-Cre-bGH-polyA
Recombinant adeno associated virus expressing Cre under the fSST promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Abcam GSK503, EZH2 methyltransferase inhibitor, 50MG
MW 526.7 Da. Potent (IC₅₀ = nM; Ki = 3 nM) and specific EZH2 methyltransferase inhibitor. Selective against EZH1 (IC₅₀ = 633 nM). At least 4000-fold selective over a panel of 20 other human methyltransferases. Highly selective against a range of human histone deacetylases, GPCRs, kinases and ion channels. Reduces cellular H3K27me3 levels. Inhibits growth of diffuse large B-cell lymphoma cells. Inhinits melanoma growth and metastasis in mouse models.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Humn PGlycoproteIn MDR1 D 96
The materials provided in the assay kit for MDR1 / Human P-Glycoprotein Drug Interaction are formatted to allow for two independent 48-well assay setups. EAch aliquot of HCT-Pgp Cells is provided as a single-use assay reagent and provides sufficient volume to dispense 48 assay wells of HCT-Pgp cells into one 96-well plate. If desired, the two aliquots of HCT-Pgp cells may be thawed, combined to generate a single cell suspension, and then dispensed into all wells of an assay plate. The kit contains two aliquots of HCT-Pgp cells and two black, sterile, collagen-coated 96-well assay plates. In addition to HCT-Pgp cells and assay plates, this kit includes Cell Recovery Medium (CRM-p) used to perform a rapid thaw of the -80°C HCT-Pgp cells, Compound Screening Medium supplemented with daunorubicin (CSM+DR) used to prepare drug treatment media, Wash Buffer, two aliquots of Lysis Reagent, and the potent reference inhibitor Tariquidar.
BIOHIPPO AAV-mscRE16-minBGpromoter-Cre-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre under the mscRE16 promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
ABclonal Technology RALA Rabbit pAb
The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins.
Apexbio Technology LLC EZ Cap Cre mRNA (ΨUTP) 1mg (1mg/mL)
Cre recombinase is a tyrosine recombinase that recognizes and catalyzes homologous recombination between two loxP DNA sites This mRNA expresses Cre recombinase and is synthesized using co-transcriptional capping to generate a Cap 1 structure making it more suitable for mammalian systems and providing higher expression efficiency Additionally the mRNA is polyadenylated and incorporates pseudouridine ( UTP) modifications which help reduce host cell immune responses and enhance mRNA stability and translation efficiency
BIOHIPPO AAV-CRH-Cre-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre under the CRH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Revvity Health Sciences Inc NEXTFLEX⢠Unique dual index barcodes (10NT, 289-384)
NEXTFLEX⢠Unique dual index barcodes (10NT, 289-384)