Oligonucleotides
Biotium DNA Ligase 1(1A9), Biotin conjugate, 0.1mg/mL
DNA Ligase I maintains the major DNA Ligase activity in proliferating cells by joining Okazaki fragments during lagging strand DNA replication. Human DNA Ligase I also has an essential role in DNA repair pathways, where it catalyzes the formation of phosphodiester bonds between adjacent 5' phosphoryl and 3' hydroxy termini at single breaks in duplex DNA molecules. In addition, DNA Ligase I plays a role in sealing nicks during excision repair. Similar to other DNA ligases, DNA Ligase I is built around a common catalytic core. Increased levels of DNA Ligase I are found in human tumors, as compared to benign tissues, as well as in peripheral blood lymphocytes. DNA Ligase I activity is altered in the chromosomal breakage deficit Bloom's syndrome (BS). Individuals with BS either have decreased levels of abnormally thermolabile DNA Ligase I or possess a dimeric form of this enzyme. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. C
Medchemexpress LLC SLC1A5/ASCT2 Antibody (YA1180) | 10 UL
SLC1A5/ASCT2 Antibody (YA1180) is a rabbit-derived, non-conjugated IgG monoclonal antibody that specifically targets SLC1A5/ASCT2. This antibody is intended for research use only and aids in the study of sodium-coupled antiporters of neutral amino acids, which are crucial for cellular transport processes.
- Rabbit host
- Recombinant, monoclonal clonality
- Human species reactivity
- Affinity purified
- Non-conjugated
- IgG isotype
- Liquid appearance
- IHC-P (Immunohistochemistry-Paraffin) application
- Stored at -20°C for 1 year
- Formulated in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide, and 0.05% BSA.
Alkali Scientific DNA & RNA Elution Buffer (EB Buffer) for PCR, Plasmid & Spin Column Cleanup, 500mL
DNA & RNA Elution Buffer is a high-purity solution designed for efficient recovery of nucleic acids during purification workflows. It is commonly used in spin column-based extraction kits for eluting DNA and RNA from silica membranes after washing steps. The buffer is formulated to be PCR compatible, ensuring that eluted nucleic acids can be directly used in downstream applications such as PCR amplification, qPCR, sequencing, and cloning without additional cleanup. Its low ionic strength helps maximize recovery while maintaining nucleic acid stability. This buffer is widely used in molecular biology laboratories for plasmid purification, genomic DNA extraction, and RNA isolation procedures where reliable and contaminant-free elution is required.
Medchemexpress LLC STING ligand-1 | 2365039-41-2 | 99.7% | 523.98 | 5 MG
STING ligand-1 is a lead STING ligand with an IC50 of 68 nM for HAQ STING. It exhibits functional inhibition of STING mediated cytokine release.
- Appearance: Solid
- Color: Off-white to light yellow
- Purity: 99.65%
- CAS number: 2365039-41-2
- Molecular weight: 523.98
- Formula: C29H27ClFNO5
- Shipping: Room temperature in continental US
- Storage: Powder at -20°C for 3 years, 4°C for 2 years; In solvent at -80°C for 6 months, -20°C for 1 month
- IC50: 68 nM (HAQ STING)
BIOHIPPO AAV-NPY-Cre-WPRE-bGH-polyA
Recombinant adeno associated virus expressing Cre under the NPY promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Biotium SOX9 / SRY-box 9(SOX9/3141R), CF488A conjugate, 0.1mg/mL
Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye col
Medchemexpress LLC PFKM Human HEK293 10ug
Recombinant human PFKM protein expressed in HEK293 cells with a C-terminal His tag, supplied as a 0.2 μm filtered solution and suitable for biochemical and functional assays; catalyzes phosphorylation of fructose-6-phosphate in glycolysis.
- Human source expressed in HEK293 cells for mammalian post-translational modifications.
- Greater than 95% purity as determined by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Supplied in buffered formulation with trehalose for enhanced stability.
- Stable at -80°C; avoid repeated freeze-thaw cycles.
- Validated specific activity: 502.29 pmol/min/μg.
American Research Products Inc PrEST Antigen MMP9
PrEST Antigen MMP9 antigen APrEST88060 for matrix metallopeptidase 9 (gelatinase B 92kDa gelatinase 92kDa type IV collagenase) Recombinant protein fragment of Human MMP9
Biotium SOX9 / SRY-box 9(SOX9/3141R), 1mg/mL
Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye col
Biotium CD43(SPN/1094), CF405S conjugate, 0.1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundan
Biotium CD43 (T-Cell Marker)(SPN/3388), CF568 conjugate, 0.1mg/mL
Recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targe
Medchemexpress LLC CD43 Human HEK293 20ug | 20ug
CD43 protein is an important leukocyte surface sialic acid protein that plays a key role in T cell regulation It has a positive impact on T cell function including activation proliferation differentiation trafficking and migration especially by helping T cells migrate to lymph nodes through ERM proteins CD43 Protein Human (HEK293 His) is the recombinant human-derived CD43 protein expressed by HEK293 with C-8 His labeled tag
Genscript Corporation CD43 His Cynomolgus
CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage CD43 is directly involved in the contact between cells participating in a series of events such as signaling adherence and host parasite interactions The induction of acute myocarditis involves the engagement of CD43 cytoplasmic tripeptide sequence KRR to ezrin-radixin-moiesin cytoskeletal proteins
BIOHIPPO AAV-hSyn-tdTomato-5'miR-30-shRNA(scramble)-3'miR-30-WPREs
Recombinant adeno associated virus expressing 5'miR-30-shRNA(scramble)-3'miR-30 fused to tdTomato under the hSyn promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Meso Scale Discovery U-PLEX Human vWF ASYQP
The Meso Scale Discovery U-PLEX Human VWF Assay is an electrochemiluminescent immunoassay for the quantitative measurement of von Willebrand Factor (VWF) in human serum plasma and cell culture supernatants This assay utilizes MSD s proprietary SULFO-TAG labels and multi-array technology to provide sensitive and reproducible quantitation of VWF with a wide dynamic range The assay requires a small sample volume and has a total assay time of approximately 3 5 hours The lower limit of detection is 1 3 ng/mL and the upper limit of quantitation is 10 000 ng/mL This assay provides a simple rapid high-throughput method for measuring VWF levels