Oligonucleotides
ATCC HCM-BROD-0229-C25; Cancer Model Metastatic; Adenocarcinoma of pancreas; Human (Homo sapiens)
A patient-derived next-generation cancer model generated by the Human Cancer Models Initiative (HCMI). HCM-BROD-0229-C25 (ATCC No. PDM-168) was isolated from metastatic adenocarcinoma of pancreas tissue. This tumor-derived model can be used in basic research and pharmacological screening applications. Data for the tumor-derived organoid model is available at the GDC. Additional molecular characterizations may be available at the GDC. Additional controlled data may be available via dbGaP.
CPC Scientific 5FAM-Lys-Glu-Asp-Pro-Asp-Tyr-Glu-Trp-Pro-Ser-NH2 (trifluoroacetate salt) 0.5MG
ONE-LETTER SEQUENCE: 5FAM-KEDPDYEWPS-NH2MOLECULAR FORMULA: C78H87N13O26MOLECULAR WEIGHT:1622.6STORAGE CONDITIONS: -20 5CRESEARCH AREA: Protein Kinases and Phosphatases
Cayman Chemical EP4 Receptrrat Reverse Tr 1ea
An Mps1 inhibitor (IC50 0.34 nM) inhibits nocodazole-induced metaphase arrest in HeLa cells (IC50 56 nM) inhibits proliferation in a panel of 86 cancer cell lines (median IC50 6.7 nM) reduces tumor area in a cisplatin-resistant A2780/CP70 ovarian cancer mouse xenograft model at 2.5 mg/kg
ABclonal Technology Non-pAct -CateninS33/S37/T41
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs) AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete Finally this protein binds to the product of the APC gene which is mutated in adenomatous polyposis of the colon Mutations in this gene are a cause of colorectal cancer (CRC) pilomatrixoma (PTR) medulloblastoma (MDB) and ovarian cancer Alternative splicing results in multiple transcript variants
Biotium SOX9 / SRY-box 9(rSOX9/2288), CF405S conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
