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Filtered Search Results
MEDCHEMEXPRESS LLC A-381393 5MG
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501872538 A-381393 5MG
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Selleck Chemical LLC Ibuprofen (NSC 256857) S1638-50mg
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Ibuprofen (NSC 256857 Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 M and 370 M respectively
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Selleck Chemical LLC Hydroxyurea S1896-200mg
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Hydroxyurea is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase Hydroxyurea activates apoptosis and autophagy Hydroxyurea is used to treat HIV infection
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Sigma Aldrich Fine Chemicals Biosciences Gentamicin sulfate salt potency: >=590 I.U. Gentamicin base per mg | 1405-41-0 | MFCD00270181 | 5G
Gentamicin sulfate salt potency: >=590 I.U. Gentamicin base per mg | 1405-41-0 | MFCD00270181 | 5G
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Research Products International Corp Carbenicillin, Disodium Salt, 100 Gram
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Carbenicillin, Disodium Salt is a semi-synthetic penicillin antibiotic effective against Gram-positive and Gram-negative bacteria. It is commonly used in molecular biology, genetic engineering, microbiology, and cell culture as a selective agent in plasmid-based cloning. It inhibits bacterial cell wall synthesis, allowing selection of cells expressing Carbenicillin resistance genes. This antibiotic prevents bacterial contamination in cell cultures and supports isolation and maintenance of resistant strains. Key features include broad-spectrum activity and stability in aqueous solutions.
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Research Products International Corp G-418 Disulfate, 25 Grams
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G-418 Disulfate, also known as Geneticin, is an aminoglycoside antibiotic derived from Micromonospora rhodorangea. It is widely used in molecular biology and cell culture as a selective agent. G-418 inhibits protein synthesis by targeting the 80S ribosome, blocking translocation. It is commonly used to select genetically modified cells that carry a G-418 resistance gene, typically introduced via plasmid vectors. This allows for the isolation and maintenance of stable transfectants in gene expression, protein production, and cell line development studies. Its selectivity makes it a key tool in genetic engineering.
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MEDCHEMEXPRESS LLC OPROZOMIB 5MG
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501872590 OPROZOMIB 5MG
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MEDCHEMEXPRESS LLC INH14 5MG
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501872526 INH14 5MG
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Alkali Scientific ALKALI SCIENTIFIC INC
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5000660739 CHLORAMPHENICOL PROTEIN BLOCK
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Alkali Scientific ALKALI SCIENTIFIC INC
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5000660766 CLINDAMYCIN PROTEIN INHIBITOR
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Medchemexpress LLC HY-10373 5mg , Trimetrexate CAS:52128-35-5 Purity:>98%
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HY-10373 5mg Trimetrexate CAS: 52128-35-5 Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer[4][5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Lodoxamide tromethamine | 63610-09-3 | 99.8% | 553.90 | 100 MG
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Lodoxamide tromethamine is a medication used for the treatment and prophylaxis of mast cell-mediated allergic diseases. It demonstrates cromolyn-like activity and can inhibit histamine release and calcium influx in mast cells. It has shown to reduce allergic responses in vivo and can decrease lung reperfusion injury. Patients treated with this compound have reported improvements in breathing, cough, sputum production, and sleep.
- Treatment and prophylaxis of mast cell-mediated allergic disease.
- Inhibits compound 48/80-induced histamine release and calcium influx in mast cells.
- Demonstrates cromolyn-like activity.
- Reduces increased respiratory frequency and decreased tidal volume induced by antigen challenge.
- Decreases lung reperfusion injury.
- Improves daytime breathing difficulty, cough, sputum production, and sleep.
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Medchemexpress LLC ESI-09 | 263707-16-0 | 99.15% | 330.77 | 100 MG
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ESI-09 is a novel noncyclic nucleotide EPAC antagonist that inhibits EPAC1 and EPAC2 activity, with IC50 values of 3.2 μM for EPAC1 and 1.4 μM for EPAC2. It exhibits increased potency in competing with 8-NBD-cAMP binding and inhibits cAMP-mediated GEF activity. ESI-09 has been shown to inhibit Akt phosphorylation and the migration of pancreatic cancer cells. It also suppresses EPAC1-mediated adhesion of PDA cells on collagen I and reduces bacterial counts in HUVECs infected with *R. australis*, protecting against infection in vivo.
- Novel noncyclic nucleotide EPAC antagonist
- Inhibits EPAC1 and EPAC2 activity
- Increased potency in 8-NBD-cAMP binding competition
- Inhibits cAMP-mediated EPAC2 and EPAC1 GEF activity
- Inhibits Akt phosphorylation
- Suppresses pancreatic cancer cell migration
- Reduces bacterial counts post-infection with *R. australis*
- Protects against *R. australis* infection in vivo
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Sigma Aldrich Fine Chemicals Biosciences Penicillin G sodium salt | 69-57-8 | MFCD00069666 | 5 g
Penicillin G sodium salt | Purity: 96.0-102.0% | Mol Wt: 356.37 | 69-57-8 | MFCD00069666 | 5 g
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Sigma Aldrich Fine Chemicals Biosciences 6-Thioguanine >=98% | 154-42-7 | MFCD00233553 | 5G
6-Thioguanine >=98% | Purity: >=98% | Mol Wt: 167.19 | 154-42-7 | MFCD00233553 | 5G
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