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Filtered Search Results
eMolecules 2049868-46-2 | Medchem Express | GSK963 | 5mg | 482203824 | HY-103028A | 230.311 | C14H18N2O
Ambeed | 333-Trifluoro-2-hydroxy-2-methylpropanoic acid | 1g | 571784984 | A327311 | 374-35-6 | MFCD00190646 | 158.076 | C4H5F3O3
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eMolecules 1222810-74-3 | Medchem Express | VU591 | 5mg | 455325952 | HY-108585A | 368.309 | C16H12N6O5
Ambeed | (2S)-2-(4-(((2-Amino-4-oxo-345678-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid | 100mg | 525877277 | A276659 | 135-16-0 | 445.436 | C19H23N7O6
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Apexbio Technology LLC Azithromycin 83905-01-5 50mg
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Azithromycin (CAS 83905-01-5) is a small-molecule inhibitor targeting the bacterial ribosomal 50S subunit It is designed to inhibit microbial protein synthesis thereby interfering with peptide translation Azithromycin exerts its biological activity primarily through inhibition of bacterial protein synthesis In in vitro studies azithromycin demonstrates antiparasitic effects by inhibiting parasite propagation with an IC50 value of approximately 8 4 M Based on these pharmacological properties azithromycin holds research potential in investigating protein synthesis mechanisms and studying antimicrobial and antiparasitic drug resistance processes
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Gold Biotechnology Inc Penicillin G Sodium Salt, USP Grade 50 g
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Penicillin G is a β-lactam antibiotic produced by the Penicillium fungus. It has shown efficacy against a variety of Streptococcus species as well as non-penicillinase producing Staphylococcus species.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000427628 PHYSCION 100MG
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Apexbio Technology LLC Ribostamycin Sulfate 53797-35-6 50mg
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Ribostamycin Sulfate (CAS 53797-35-6) is a small-molecule inhibitor targeting the bacterial 30S ribosomal subunit It is designed to disrupt bacterial protein synthesis thereby inhibiting bacterial growth Ribostamycin Sulfate exerts its biological activity primarily through binding to the 30S ribosomal subunit and impairing protein translation In in vitro assays Ribostamycin typically demonstrates inhibitory activity within the micromolar concentration range though specific IC50 values vary depending on bacterial species and experimental conditions Based on these pharmacological properties Ribostamycin Sulfate holds research potential in the study of bacterial protein translation mechanisms evaluation of antibiotic resistance phenotypes and antimicrobial susceptibility testing in microbial strains
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Medchemexpress LLC Magainin 2 | 108433-95-0 | 98.8% | 2466.90 | 500 UG
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Magainin 2, an antimicrobial peptide isolated from the skin of the African clawed frog, Xenopus laevis, exhibits antibiotic activity against numerous gram-negative and gram-positive bacteria, as well as protozoa. It exerts cytotoxicity by interacting with anionic phospholipids abundant in bacterial membranes, permeabilizing cell membranes with low toxicity to mammalian cells.
- Exhibits broad-spectrum antibiotic activity against bacteria and protozoa
- Interacts with anionic phospholipids in bacterial membranes
- Induces morphological changes in Escherichia coli
- Permeabilizes bacterial cell membranes without significant toxicity to mammalian cells
- Disrupts osmotic balance in protozoa like Paramecium caudatum
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Medchemexpress LLC HZX-02-059 (methuosis inducer 1) | 2240205-30-3 | 99.4% | 487.48 | 10 MG
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HZX-02-059 is a potent methuosis inducer and a dual-target PIKfyve/tubulin inhibitor, demonstrating anticancer activity. This compound primarily disrupts the balance of endocytosis and exocytosis, leading to the formation of numerous vesicles and inducing cell death.
- Induces cell vacuolization and promotes apoptosis
- Downregulates the p53 pathway
- Inhibits PI3K/AKT phosphorylation
- Inhibits c-Myc and NF-κB transcription
- Exhibits broad spectrum cytotoxicity against various human cancer cell lines
- For research use only
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Medchemexpress LLC CHMFL-PI3KD-317 | 2244992-76-3 | 98.0% | 494.03 | 50 MG
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CHMFL-PI3KD-317 is a highly potent, selective, and orally active PI3Kδ inhibitor. It exhibits high selectivity over other class I, II, and III PIKK family isoforms and effectively inhibits PI3Kδ-mediated Akt T308 phosphorylation. The compound also demonstrates significant antiproliferative effects on various cancer cells and shows favorable oral bioavailability in vivo.
- Highly potent and selective PI3Kδ inhibitor.
- Exhibits over 10-1500 fold selectivity over other PIKK family isoforms.
- Inhibits PI3Kδ-mediated Akt T308 phosphorylation in Raji cells.
- Demonstrates antiproliferative effects on cancer cells.
- Shows favorable oral bioavailability and acceptable half-life in Sprague-Dawley rats.
- Inhibits the growth of MOLM-14 tumors in mice without mortality or significant weight loss.
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Medchemexpress LLC Oxcarbazepine | 28721-07-5 | 99.9% | C15H12N2O2 | 100 MG
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Oxcarbazepine is a sodium channel blocker that significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. It also has anti-cancer and anticonvulsant effects, making it suitable for research and analytical applications.
- Sodium channel blocker
- Inhibits glioblastoma cell growth
- Induces apoptosis or G2/M arrest
- Anti-cancer effects
- Anticonvulsant effects
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Enzo Life Sciences Piceatannol (1mg). CAS: 10083-24-6
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Originally isolated from Euphorbia lagascae. Selective protein tyrosine kinase Syk inhibitor (IC50~10 µM). In RBL-2H3 cells the selective inhibition of Syk by piceatannol results in inhibition of FcεR1-mediated signaling. Activator of human deacetylase SIRT1. Alternative name: 3,4,3',5'-Tetrahydroxy-trans-stilbene. Formula: C14H12O4. MW: 244.2. Purity: ≥98% (HPLC (UV)). Appearance: Off-white to light pink crystalline solid. Solubility: Soluble in DMSO (>50mg/ml), methanol (>50mg/ml), dioxan (>50mg/ml), acetonitrile (>50mg/ml); slightly soluble in water (1mg/ml). Long Term Storage: +4°C. Handling: Protect from light and oxygen.
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Apexbio Technology LLC Tobramycin Sulfate 49842-07-1 50mg
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Tobramycin Sulfate (49842-07-1) is a broad-spectrum aminoglycoside antibiotic targeting bacterial ribosomal subunits It is designed to disrupt protein synthesis thereby inhibiting bacterial growth Tobramycin Sulfate exerts its biological activity primarily through binding to bacterial ribosomal subunits and interfering with protein synthesis It demonstrates inhibitory activity predominantly against Gram-negative bacteria with reported IC50 values typically ranging from 0 5 to 8 g/mL depending on bacterial species and experimental conditions Based on these pharmacological properties Tobramycin Sulfate holds research potential in assessing susceptibility profiles investigating resistance mechanisms and establishing bacterial infection models in biomedical research
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Enzo Life Sciences Duvelisib (free base) (100mg). CAS: 1201438-56-3
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Duvelisib is an orally bioavailable and highly selective inhibitor of PI3K-δ and PI3K-γ with IC50 values of 0.36 nM and 19.6 nM, respectively. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
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eMolecules 209219-38-5 | Medchem Express | Nastorazepide | 5mg | 446268750 | HY-17617 | MFCD26142609 | 520.63 | C29H36N4O5
Medchem Express | SU3327 | 5mg | 518570903 | HY-107597 | 40045-50-9 | MFCD01927019 | 261.290 | C5H3N5O2S3
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377444 TCS JNK 5A 100MG
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