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Filtered Search Results
STEMCELL Technologies Rapamycin, Size: 1 mg
Inhibit mammalian target of rapamycin (mTOR) signaling with Rapamycin. This FKBP-12-inhibiting antibiotic shows antifungal activity against Candida albicans and other fungi (Vézina et al. J Antibiot (Tokyo), 1975); inhibits growth of MDA-MB-468 human breast cancer cells in vitro (Akcakanat et al. Mol Cancer, 2009; and inhibits tumor growth in a mouse xenograft model in vivo (Akcakanat et al. Mol Cancer, 2009). Its immunosuppressive effects are mediated through inhibition of IL-2 signaling that is critical for T-cell proliferation and activation (Gibbons et al. Semin Oncol, 2009; Kay et al. Immunology, 1991). Rapamycin is supplied as a crystalline solid with ≥ 95% purity; Molecular weight 914.2 g/mol; CAS number 53123-88-9. Visit STEMCELL.com for more information and related products.
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Medchemexpress LLC Acp-5862 | 2230757-47-6 | 98.3% | 481.51 g/mol | C26H23N7O3 | 5 MG
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ACP-5862 is the major active, circulating metabolite of acalabrutinib. It is a pyrrolidine ring-opened small molecule that potently inhibits Bruton tyrosine kinase (BTK) with an IC50 of 5.0 nM and displays weak time-dependent inactivation of CYP3A4 and CYP2C8.
- Potent BTK inhibition with reported IC50 of 5.0 nM.
- Useful for metabolite profiling and pharmacology studies.
- High reported purity (≈98.3%) suitable for research use.
- Available in small milligram package sizes for discovery work.
- Storage-stable under recommended powder and solvent conditions.
- Well characterized: molecular weight 481.51 and formula C26H23N7O3.
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Medchemexpress LLC 9(E)-Erythromycin A oxime | 111321-02-9 | MFCD08062410 | 5mg
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(9E)-Erythromycin A oxime is a metabolite of Roxithromycin (HY-B0435) Roxithromycin is a semi-synthetic macrolide antibiotic
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Medchemexpress LLC HY-100521 5mg Medchemexpress, GKI-1 CAS: Purity:>98%
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Medchemexpress, HY-100521 5mg GKI-1 CAS: GKI-1 is a Greatwall (GWL) kinase inhibitor with IC50s of 4.9 and 2.5 µM against hGWLFL and hGWL-KinDom, respectively. GKI-1 robustly inhibits ROCK1 with an IC50 of 11 µM, but only weakly affected PKA. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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MEDCHEMEXPRESS LLC TOSEDOSTAT 5MG
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501873087 TOSEDOSTAT 5MG
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MEDCHEMEXPRESS LLC ROMIDEPSIN 5MG
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501873135 ROMIDEPSIN 5MG
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MEDCHEMEXPRESS LLC BD-1047 DIHYDROBROMIDE 5MG
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501873537 BD-1047 DIHYDROBROMIDE 5MG
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MEDCHEMEXPRESS LLC VALSARTAN 10MG
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501873641 VALSARTAN 10MG
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MEDCHEMEXPRESS LLC HALOFANTRINE HYDROCHLORIDE 10M
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501874017 HALOFANTRINE HYDROCHLORIDE 10M
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MEDCHEMEXPRESS LLC TASOSARTAN 10MG
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501874023 TASOSARTAN 10MG
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MEDCHEMEXPRESS LLC MINOXIDIL 1G
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501874042 MINOXIDIL 1G
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MEDCHEMEXPRESS LLC HEPARAN SULFATE 5MG
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501871920 HEPARAN SULFATE 5MG
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MEDCHEMEXPRESS LLC FX1 5MG
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501871957 FX1 5MG
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MEDCHEMEXPRESS LLC RAPAMYCIN 50MG
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501871970 RAPAMYCIN 50MG
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MEDCHEMEXPRESS LLC OSS 128167 5MG
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501872173 OSS 128167 5MG
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