Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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6,151 – 6,165 of 6,971 results

6,151

Research Products International Corp PLICAMYCIN [MITHRAMYCIN A], 5 MG

Plicamycin, also known as mithramycin or Mithracin, is an antineoplastic antibiotic produced by the bacterium Streptomyces plicatus. Plicamycin binds to DNA and inhibits both DNA and RNA synthesis. It accomplishes this by binding to the guanine-cytosine (GC) rich regions of DNA, preventing the transcription of genetic information into RNA. As a result, the synthesis of proteins and other essential cellular components is disrupted.

Researchers may employ plicamycin to investigate its effects on gene expression, cell cycle regulation, and apoptosis in cancer cells.

WARNING! This product can expose you to Pilcamycin, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.

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6,152

Chem-Impex International, Inc. Vancomycin hydrochloride | 1404-93-9 | MFCD03613611 | 5G

Vancomycin hydrochloride, 1404-93-9, MFCD03613611, 5G

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6,153

Research Products International Corp 17-AAG [17(Allyamino)-17-demothoxygeldanamycin], 1 Milligrams

17-AAG (17-Allylamino-17-demethoxygeldanamycin) is a synthetic derivative of geldanamycin. Like geldanamycin, 17-AAG is recognized for its role as an inhibitor of heat shock protein 90 (Hsp90), a molecular chaperone involved in protein folding and stabilization.

It is often used as a tool to study Hsp90-dependent processes. By inhibiting Hsp90, 17-AAG impacts the stability and function of various client proteins, many of which are involved in critical cellular processes, including signal transduction and cell cycle regulation. Similar to geldanamycin, 17-AAG is particularly relevant in cancer research, as Hsp90 is often crucial for the stability of oncoproteins.

Researchers use 17-AAG to explore the molecular mechanisms of Hsp90 inhibition, with potential applications in understanding cancer biology and developing therapeutic strategies.

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6,154

Research Products International Corp Cefsulodin, Sodium Salt, 5 Grams

Cefsulodin Sodium Salt is a cephalosporin antibiotic. Cefsulodin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This disruption interferes with the final stages of peptidoglycan synthesis in the bacterial cell wall, leading to structural instability and eventual cell lysis.

Effective against a range of Gram-negative bacteria, it is particularly useful in the isolation and selection of these bacteria in microbiological and research settings. Commonly used in culture media for the growth and identification of specific bacterial strains.

Additionally, it is often employed as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic. Its inclusion allows for the specific growth of Gram-negative bacteria lacking resistance to cefsulodin.

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6,155

AdipoGen Puromycin . dihydrochloride Chemical. CAS: 58-58-2

Puromycin . dihydrochloride , AdipoGen Life Sciences. Chemical. CAS: 58-58-2. Formula: C22H29N7O5 . 2HCl. MW: 471.5 . 72.9. Isolated from Streptomyces alboniger. Aminonucleoside antibiotic. Protein synthesis inhibitor. Disrupts peptide transfer on ribosomes (acting as an acyl-tRNA analog) causing premature chain termination during translation. Translational inhibitor in prokaryotic and eukaryotic cells in both in vitro and in vivo systems. Inhibits the transport of proteins into the mitochondria in vitro. Reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase (metallopeptidase). Apoptosis inducer. Inhibits the growth of Gram-positive bacteria, various animal and insect cells. Fungi and Gram-negative bacteria are resistant due to the low permeability to the antibiotic. Antineoplastic agent. Used in cell biology as selective agent in cell culture systems.

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6,156

Chem-Impex International, Inc. Cephalexin hydrate | 15686-71-2 | MFCD00167148 | 5G

Cephalexin hydrate, 15686-71-2, MFCD00167148, 5G

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6,157

Chem-Impex International, Inc. Cefsulodin sodium salt hydrate | MFCD29472517 | 5G

Cefsulodin sodium salt hydrate, MFCD29472517, 5G

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6,158

Research Products International Corp Meropenem Trihydrate, 1 Gram

Meropenem is a broad-spectrum antibiotic. It is a carbapenem antibiotic that inhibits bacterial cell wall synthesis. It acts by binding to penicillin-binding proteins (PBPs), enzymes involved in the final stages of peptidoglycan synthesis in the bacterial cell wall. This interference leads to structural instability and eventual cell lysis.

Meropenem may be used as a tool to study antibiotic susceptibility patterns of bacteria or as a selective agent in culture media to isolate bacteria sensitive to this antibiotic.

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6,159

AdipoGen Colistin sulfate (USP Grade),Chemical. CAS: 1264-72-8

Colistin sulfate (USP Grade), AdipoGen Life Sciences. Chemical. CAS: 1264-72-8. Formula: 2(C52H98N16O13) . 5(H2SO4) (unspec.). MW: 2801.7. Isolated from Bacillus polymyxa. Very potent polymyxin antibiotic. Has only one amino acid difference compared to polymyxin B. Antimicrobial. Targets the lipopolysaccharide (LPS) of the outer membrane of Gram-negative bacteria. Competitively displaces divalent cations (Ca2+ and Mg2+) from the negatively-charged phosphate groups LPS, causing disruption of the membrane. This increases the permeability of the cell envelope, leakage of cell contents, leading to apoptosis and cell death. Used against multidrug-resistant Gram-negative bacterial infections.

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6,160

Chem-Impex International, Inc. Chlortetracycline hydrochloride | 64-72-2 | MFCD26142699 | 25G

Chlortetracycline hydrochloride, 64-72-2, MFCD26142699, 25G

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6,161

Research Products International Corp G-418 Disulfate, 25 Grams

G-418 Disulfate, also known as Geneticin, is an aminoglycoside antibiotic derived from Micromonospora rhodorangea. It is widely used in molecular biology and cell culture as a selective agent. G-418 inhibits protein synthesis by targeting the 80S ribosome, blocking translocation. It is commonly used to select genetically modified cells that carry a G-418 resistance gene, typically introduced via plasmid vectors. This allows for the isolation and maintenance of stable transfectants in gene expression, protein production, and cell line development studies. Its selectivity makes it a key tool in genetic engineering.

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6,162

Research Products International Corp Penicillin G Potassium Salt, 25 Grams

Penicillin G potassium salt is a member of the penicillin class of antibiotics and is effective against a variety of gram-positive bacteria. As a narrow-spectrum antibiotic belonging to the beta-lactam class, it inhibits the synthesis of bacterial cell walls. It interferes with the formation of peptidoglycan, a crucial component of the bacterial cell wall. This weakens the cell wall and leads to the eventual rupture of the bacterial cell.

Penicillin G is effective against a wide range of Gram-positive bacteria, including Streptococcus, Staphylococcus, and some other species. However, it is not effective against Gram-negative bacteria due to their different cell wall structure.

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6,163

Chem-Impex International, Inc. Bacitracin from Bacillus licheniformis | 1405-87-4 | MFCD27976769 | 5G

Bacitracin from Bacillus licheniformis, 1405-87-4, MFCD27976769, 5G

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6,164

Chem-Impex International, Inc. Geneticin disulfate salt | 108321-42-2 | MFCD05664725 | 5G

Geneticin disulfate salt, 108321-42-2, MFCD05664725, 5G

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6,165

Sigma Aldrich Fine Chemicals Biosciences Spectinomycin Ready Made S

Chemical structure aminoglycoside

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Antibiotics

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Research Products International Corp PLICAMYCIN [MITHRAMYCIN A], 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp 17-AAG [17(Allyamino)-17-demothoxygeldanamycin], 1 Milligrams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Cefsulodin, Sodium Salt, 5 Grams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Meropenem Trihydrate, 1 Gram Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp G-418 Disulfate, 25 Grams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Penicillin G Potassium Salt, 25 Grams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More