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Filtered Search Results
eMolecules N-(Azido-PEG10)-N-PEG10-t-butyl ester | Broadpharm |1095.329 | C49H98N4O22 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 500mg | 603111811
N-(Azido-PEG10)-N-PEG10-t-butyl ester | Broadpharm |1095.329 | C49H98N4O22 | 98.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 500mg | 603111811
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eMolecules 865362-74-9 | 5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine | MFCD14585805 | 10mg
Ambeed | 5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine | 10mg | 514326560 | A867944 | 865362-74-9 | MFCD14585805 | 327.351 | C18H13N7
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Cell Signaling Technology Brefeldin A 5 mg
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Brefeldin A 5 mg
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Medchemexpress LLC ESI-09 | 263707-16-0 | 99.15% | 330.77 | 100 MG
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ESI-09 is a novel noncyclic nucleotide EPAC antagonist that inhibits EPAC1 and EPAC2 activity, with IC50 values of 3.2 μM for EPAC1 and 1.4 μM for EPAC2. It exhibits increased potency in competing with 8-NBD-cAMP binding and inhibits cAMP-mediated GEF activity. ESI-09 has been shown to inhibit Akt phosphorylation and the migration of pancreatic cancer cells. It also suppresses EPAC1-mediated adhesion of PDA cells on collagen I and reduces bacterial counts in HUVECs infected with *R. australis*, protecting against infection in vivo.
- Novel noncyclic nucleotide EPAC antagonist
- Inhibits EPAC1 and EPAC2 activity
- Increased potency in 8-NBD-cAMP binding competition
- Inhibits cAMP-mediated EPAC2 and EPAC1 GEF activity
- Inhibits Akt phosphorylation
- Suppresses pancreatic cancer cell migration
- Reduces bacterial counts post-infection with *R. australis*
- Protects against *R. australis* infection in vivo
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Medchemexpress LLC Lyn-1604 dihydrochloride | 2310109-38-5 | 99.6% | 657.54 g/mol | C33H45Cl4N3O2 | 50 MG
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LYN-1604 dihydrochloride is a small-molecule activator of UNC-51-like kinase 1 (ULK1) intended for biochemical and cellular research into autophagy and triple-negative breast cancer. The compound activates ULK1 (EC50 = 18.94 nM), shows cellular potency (IC50 = 1.66 μM in MDA-MB-231 cells), and has a measured binding affinity (KD = 291.4 nM). Supplied as the dihydrochloride salt at high purity for assay and dose-response studies.
- Potent ULK1 activator (EC50 = 18.94 nM).
- Demonstrated cellular activity (IC50 = 1.66 μM in MDA-MB-231 cells).
- Measured binding affinity to ULK1 (KD = 291.4 nM).
- High purity suitable for biochemical and cellular assays (99.55%).
- Available in multiple sizes for dose-range and scale-up studies.
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Medchemexpress LLC HY-10492 10mg Medchemexpress, Dinaciclib CAS:779353-01-4 Purity:>98%
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Medchemexpress, HY-10492 10mg Dinaciclib CAS:779353-01-4 Dinaciclib (SCH 727965) is a potent inhibitor of CDK, with IC50s of 1 nM, 1 nM, 3 nM, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Ampicillin trihydrate | 7177-48-2 | 99.9% | 100 G
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Ampicillin trihydrate is a broad-spectrum beta-lactam antibiotic effective against various gram-positive and gram-negative bacteria. For research use only.
- It inhibits the growth of E. coli of swine origin in a dose-dependent manner, with an effective inhibitory concentration of 2.5 uG/mL.
- It is effective in alleviating hemorrhagic enteritis symptoms in pigs.
- After oral administration, ampicillin trihydrate produces maximum concentrations in bile twice as high as in serum, and peak concentration in portal blood is twice as high as in peripheral blood.
- It also provides neuroprotection against ischemia-reperfusion brain injury by reducing MMPs activities and increasing GLT-1 expression, significantly reducing medial hippocampal cell death following global forebrain ischemia.
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Medchemexpress LLC Menin-MLL inhibitor 20 | 2448173-47-3 | 98.8% | 100 MG
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Menin-MLL inhibitor 20 is an irreversible menin-MLL interaction inhibitor that exhibits antitumor activities. It is referenced in WO2020142557A1, Intermediate 6.
- Irreversible menin-MLL interaction inhibitor
- Exhibits antitumor activities
- Molecular weight: 612.72
- Formula: C33H40N8O4
- Appearance: Light yellow to yellow solid
- Soluble in DMSO
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eMolecules 460746-46-7 | Medchem Express | ABT-239 | 5mg | 446260808 | HY-12195 | MFCD13248643 | 330.431 | C22H22N2O
ChemScene | 2-Fluoro-3-nitrobenzaldehyde | 100mg | 559781971 | CS-W003540 | 96516-29-9 | MFCD08669885 | 169.111 | C7H4FNO3
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Apexbio Technology LLC Ciclopirox ethanolamine,50mg CAS# 41621-49-2
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Ciclopirox ethanolamine, a broad-spectrum antifungal agent, inhibits dermatophytes and yeasts pathogenic with a minimal inhibitory concentration (MIC) of 0.98-3.9 μg/mL.Ciclopirox ethanolamine, working as an iron chelator, suppresses a substantial number of clinically relevant dermatophytes, yeasts, and molds, including the frequently azole-resistant Candida species Candida glabrata, Candida krusei, and Candida guilliermondii. Moreover, Ciclopirox has been proved to inhibit a wide range of bacteria in humans, including many gram-positive and gram-negative species pathogenic bacteria. [1] Other sizes are also available. Please inqury us for quote.
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Medchemexpress LLC HY-107414 5mg Medchemexpress, SKA-121 CAS:1820708-73-3 Purity:>98%
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Medchemexpress, HY-107414 5mg SKA-121 CAS:1820708-73-3 SKA-121 is a selective KCa3.1 activator. SKA-121 exhibits EC50s of 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Est73502 monohydrochloride | 2535970-65-9 | 99.6% | C19H27ClF2N2O2 | 10MG
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EST73502 monohydrochloride is the hydrochloride salt of EST73502, a research chemical described as a selective, orally active, blood-brain barrier penetrant dual μ-opioid receptor agonist and σ1 receptor antagonist. It is provided for laboratory research use; consult the supplier datasheet and safety data sheet for handling, storage, and certificate of analysis details.
- Hydrochloride salt form for improved solubility.
- Reported molecular formula C19H27ClF2N2O2.
- Molecular weight 388.88 g/mol.
- High reported purity in distributor listings; verify with certificate of analysis.
- Intended for research use only; not for human or veterinary use.
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Apexbio Technology LLC Rifampin(Synonyms: Rifampicin, Rifaldazine, Rifadin, Rimactane, Rifoldin, Rofact, Rifamycin AMP, Riforal), 1g, CAS: 13292-46-1.
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Rifampin (CAS 13292-46-1) is an antibiotic belonging to the rifamycin family characterized by bactericidal activity via selective inhibition of bacterial DNA-dependent RNA polymerase This inhibition disrupts transcriptional initiation by preventing RNA synthesis leading to impaired bacterial protein biosynthesis and subsequent cell death In biomedical research rifampin serves as an essential tool for investigations into bacterial resistance mechanisms transcriptional regulation and synthetic biology studies that rely on specific transcription inhibition
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Medchemexpress LLC HY-101068 100mg Medchemexpress, TOFA RMI14514;MDL14514 CAS:54857-86-2 Purity:98%
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Medchemexpress,HY-101068 100mg TOFA RMI14514;MDL14514 CAS:54857-86-2 Formula:C19H32O4 TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ). Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 251349-54-9 | Medchem Express | Antibiotic-5d | 5mg | 446256178 | HY-100833 | MFCD22371193 | 298.36 | C13H18N2O4S
Medchem Express | Tasimelteon | 5mg | 446264581 | HY-14803 | 609799-22-6 | MFCD09033789 | 245.322 | C15H19NO2
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