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The CD4 protein is an integral membrane glycoprotein that plays a key role in immune responses In T cells it serves as a coreceptor for MHC class II molecules interacting with T cell receptors and initiating intracellular signaling pathways CD4 Protein Human (HEK293 Fc) is the recombinant human-derived CD4 protein expressed by HEK293 with C-hFc labeled tag
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PDGF-BB Protein Rat is a member of PDGF family which promotes cell proliferation survival and migration through binding to the tyrosine kinase PDGF receptor
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MEC/CCL28 Protein Mouse is a CC chemokine that is present in almost all mucosal tissues and acts as a unifying immunostimulant on mucosal surfaces CCL28 can bind to CCR3 and CCR10 to mediate immune responses viral infections cancer and antimicrobial effects MEC/CCL28 Protein Mouse is a recombinant mouse MEC/CCL28 (S20-R130) protein expressed by E coli[1][2]
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CD4 Protein is expressed on the surface of helper T cells It plays a key role in immune responses by binding to major histocompatibility complex class II molecules on antigen-presenting cells facilitating T cell activation and cytokine production CD4 Protein is also involved in immune regulation and tolerance Understanding its functions can aid in developing therapies for autoimmune diseases and immunodeficiencies CD4 Protein Rat (HEK293 His) is the recombinant rat-derived CD4 protein expressed by HEK293 with C-His labeled tag
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FGF-13 protein is a microtubule-binding protein that directly binds and stabilizes tubulin and affects microtubule polymerization It exerts negative regulation on axonal and leading process branches which are critical for neuronal polarization and migration in the cerebral cortex and hippocampus FGF-13 Protein Human is the recombinant human-derived FGF-13 protein expressed by E coli with tag free
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ACE2 is an important carboxypeptidase in the renin-angiotensin system that complexly regulates cardiovascular homeostasis It specifically converts angiotensin I to angiotensin 1-9 and angiotensin II to angiotensin 1-7 exerting antihypertrophic and vasodilatory effects ACE2 Protein Rat (HEK293 His) is the recombinant rat-derived ACE2 protein expressed by HEK293 with C-His labeled tag
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IFN-lambda 1 (IL-29) is a member of the Type-III interferon family IFN-lambda 1 signals through a heterodimeric receptor complex comprising IFN receptor 1 (IFNLR1) and IL-10 receptor subunit- (IL-10RB) When IFN-lambda 1 binds with the receptor complex Jak1 and Tyk2 will be activated and leads to subsequent tyrosine phosphorylation of the IFN- R1 and activation of STAT1 and STAT2[1] IFN-lambda 1 modulates immunity in infections and autoimmune diseases[2] IFN-lambda 1/IL-29 Protein Human (HEK293 His) is a recombinant human IFN-lambda 1 (G20-T200) with C-terminal 10 His tag which is produced in HEK293
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CD36 is a multifunctional glycoprotein that binds to proteins such as thrombospondin fibronectin collagen beta-amyloid and oxidized low-density lipoprotein as well as lipid molecules such as anionic phospholipids and long-chain phospholipids CD36 regulates angiogenesis inflammatory responses fatty acid metabolism taste dietary fat processing and acts as a TLR4 TLR6 heterodimer coreceptor to mediate inflammatory responses regulate immune responses and bacterial absorption CD36 Protein Mouse (HEK293 His) is the recombinant mouse-derived CD36 protein expressed by HEK293 with C-His labeled tag
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RSPO1/R-spondin-1 is a secreted glycoprotein RSPO1/R-spondin-1 binds to LGR4/5/6 receptors and ZNRF3/E3 ubiquitin ligases inhibits Wnt receptor degradation stabilizes -catenin and promotes its nuclear translocation and activates target gene transcription RSPO1/R-spondin-1 Human promotes intestinal organoid survival induces pancreatic -cell proliferation to improve diabetes enhances osteogenic differentiation of mesenchymal stem cells to treat osteoporosis and inhibits bone erosion in arthritis models RSPO1/R-spondin-1 Protein Human (HEK293 His) is a recombinant RSPO1/R-spondin-1 protein expressed by HEK293 with a C-His tag
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PDGF-DD Protein Human (CHO) is a member of the PDGF family specifically binds to and activates its cognate receptor PDGFR- and participates in regulating cancer proliferation transformation and invasion through activating multiple downstream oncogenic pathways resulting in tumor development and progression
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CD40 protein is a TNFSF5/CD40LG receptor that transduces signals through TRAF6 and MAP3K8-mediated pathways activates ERK in macrophages and B cells and induces immunoglobulin secretion CD40 exists as monomers and homodimers and interacts with TRAF proteins (TRAF1 TRAF2 TRAF3 TRAF5 and TRAF6) CD40 Protein Human (HEK293 Fc) is the recombinant human-derived CD40 protein expressed by HEK293 with C-hFc labeled tag
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MME proteins exhibit thermolysin-like specificity and primarily degrade polypeptides of up to 30 amino acids Crucially it plays a key role in cleaving the Gly-Phe bond to degrade opioid peptides including Met-enkephalin and Leu-enkephalin MME Protein Human (HEK293) is the recombinant human-derived MME protein expressed by HEK293 with tag free
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MME proteins exhibit thermolysin-like specificity and primarily degrade polypeptides of up to 30 amino acids Crucially it plays a key role in cleaving the Gly-Phe bond to degrade opioid peptides including Met-enkephalin and Leu-enkephalin MME Protein Human (HEK293) is the recombinant human-derived MME protein expressed by HEK293 with tag free
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