Cell Culture Growth Factors and Hormones
AdipoGen HGF human rec
Protein. Human HGF 692aa. Source Sf9 cells. Lyophilized. Purity >90% SDS-PAGE. Human hepatocyte growth factor HGF is synthesized as a biologically inactive single chain precursor, which is cleaved by a specific, extracellular serum serine protease to a fully active heterodimer. It stimulates the motility and invasion of several cancer cell types and can induce angiogenesis. All biological responses induced by HGF are elicited by binding to its transmembrane tyrosine kinase receptor. HGF function is essential for normal development. Knockout studies have demonstrated that both ligand and receptor deficient mice display an embryonic lethal phenotype. HGF synergizes with basic FGF in the induction of angiogenesis. HGF is a potent mitogen for mature parenchymal hepatocyte cells and is a pleiotrophic cytokine. It acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.
FUJIFILM BIOSCIENCES INC Human Myostatin (GDF-8), Recombinant Protein, Shenandoah Biotechnology, 100 ug vial
Myostatin, also known as GDF-8, is a conserved member of the TGF-beta superfamily. Myostatin is an essential regulator of skeletal muscle mass and cardiac muscle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscle growth by determining muscle fiber number and size. Myostatin binds one of the two activin type II receptors (ACTRIIA or ACTRIIB) to activate SMAD signaling. Myostatin also activates MAPK signaling through TAK1-MKK6 and Ras pathways. Inhibition of myostatin increases muscle mass in a number of human disease animal models, such as muscular dystrophy.
Medchemexpress LLC FGF-21 Human His 2ug
Recombinant human fibroblast growth factor 21 (FGF-21) is a His-tagged protein expressed in E. coli and supplied as a lyophilized powder for biochemical and cell-based research. The protein is characterized for purity and molecular weight, and is intended for studies of metabolic regulation, receptor interactions, and functional assays.
American Research Products Inc Human NerVe growth factor NGF
Human NerVe growth factor NGF ELISA kit from CUSABIO Detection Range 6 86 pg/ml-5000 pg/ml Sensitivity 6 86 pg/ml Sample serum plasma cell culture supernates tissue homogenates cell lysates Method Sandwich
Medchemexpress LLC FGF-21 Human CHO 2ug
FGF-21 Protein Human (CHO His) is a polypeptide chain containing the C-termimal His tag produced in CHO cells FGF-21 Protein Human (CHO His) is a member of the broblast growth factor (FGF) subfamily acts as a metabolic regulator with pleiotropic effects
FUJIFILM BIOSCIENCES INC Human FGF-21, Recombinant Protein, Shenandoah Biotechnology, 1 mg vial
Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and B-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.
Genscript Corporation FGF-R4 Fc Chimera Human
Fibroblast growth factor receptor 4(FGFR4) also known as CD334 (cluster of differentiation 334) is a member of the fibroblast growth factor receptor family where amino acid sequence is highly conserved between members and throughout evolution A full-length representative protein would consist of an extracellular region composed of three immunoglobulin-like domains a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain The extracellular portion of the protein interacts with fibroblast growth factors setting in motion a cascade of downstream signals ultimately influencing mitogenesis and differentiation
Medchemexpress LLC IGF-I R Rat HEK293 2ug | 2ug
Igf1r Protein a cell surface receptor is involved in growth regulation and development Dysregulation of Igf1r Protein has been linked to diseases like cancer and growth disorders Targeting Igf1r Protein may offer potential therapeutic interventions in these conditions by modulating cell growth inhibiting tumor progression and managing growth-related disorders IGF-I R Protein Rat (HEK293 His) is the recombinant rat-derived IGF-I R protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC FGF-12 Human 181a. 100ug
Recombinant human FGF-12 (181 amino acids) is a His-tagged protein expressed in E. coli and supplied as a lyophilized powder for research use. It modulates neuronal voltage-gated sodium channels and is provided with analytical quality data supporting purity, molecular weight, endotoxin level, and biological activity.
- High purity (≥95%) as determined by reducing SDS-PAGE.
- N-terminal 6xHis tag for affinity purification and detection.
- Lyophilized from 50 mM Tris-HCl, 300 mM NaCl, 500 mM arginine, pH 8.0 to enhance stability.
- Low endotoxin (<1 EU/μg) suitable for cell-based assays.
- Demonstrated biological activity (ED50 1.702 ng/mL in NIH-3T3 assay).
- Recommended reconstitution at ≥100 μg/mL and storage in aliquots at -20°C or -80°C.
Meso Scale Discovery UPLEX HUM FGF basic ASY384
The Meso Scale Discovery U-PLEX Human FGF Basic 384-Well Assay is a multiplex immunoassay for measuring FGF basic in human serum plasma and cell culture supernatants It uses electrochemiluminescence detection offering high sensitivity a dynamic range of up to 5 logs and low sample consumption The assay measures FGF basic levels from 0 06 to 2500 pg/mL with just 10 L of sample per well Provided in a 384-well plate it includes analyte-specific antibodies on carbon electrodes and takes about 3 hours to complete enabling sensitive reproducible high-throughput quantification from small samples
Meso Scale Discovery U-PLEX Mouse FGF-21 ASYQP
The Meso Scale Discovery U-PLEX Mouse FGF-21 Assay Kit is an electrochemiluminescent immunoassay for the quantitative measurement of FGF-21 in mouse serum plasma and cell culture supernatants The assay uses MSD s proprietary SULFO-TAG labels and multi-array technology to provide sensitive and reproducible results with low sample volume requirements The kit includes a 96-well plate coated with capture antibodies specific for mouse FGF-21 detection antibodies conjugated to MSD SULFO-TAG calibrators and sample diluent The assay has a typical sensitivity of 1 5 pg/mL and an upper limit of quantification of 10 000 pg/mL
Bioworld 6-Benzylaminopurine (6-BAP), 5 g
6-Benzylaminopurine (6-BAP)Synonyms: N6-Benzyladenine; N-(phenylmethyl)-1H-purin-6-amine Cytokine growth regulatorPlant tissue culture testedSoluble in 1M NaOHSolubilizeat 1 mg/mLin 0.1N KOH
Sino Biological Recombinant Human PDGF-C Protein (His Tag)
A DNA sequence encoding the mature form of human PDGF-C (NP_057289.1) (Val 235-Gly 345) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
Avanti Polar Lipids BRAIN EXTRACT POLAR 500MG
Brain Polar Lipid Extract (Porcine) 500mg. 5 x 100mg. CAS# 86088-88-2