Cell Culture Growth Factors and Hormones
Sigma Aldrich Fine Chemicals Biosciences Epidermal Growth factor fr
Epidermal Growth factor (EGf) is a small mitogenic polypeptide (A¼6kDa) present in many mammalian species and distributed throughout a wide number of tissues and body fluids. four ErbB (HER) family receptor tyrosine kinases including EGfR/ErbB1 ErbB2 ErbB3 and ErbB4 mediate responses to EGf family members. Human and mouse EGfs are very similar but not identical in their physical and chemical properties. Of the 53 amino acid residues comprising each of the two polypeptides 37 are common to both molecules and three disulfide bonds are formed in the same relative positions.
Meso Scale Discovery U-PLEX Mouse TGF-B3 ASY
The Meso Scale Discovery U-PLEX Mouse TGF-beta3 Assay Kit is an electrochemiluminescent immunoassay for quantifying mouse TGF-beta3 in serum plasma cell culture supernatants and other samples It uses the QuickPlex SQ 120 instrument and multi-array technology for sensitive detection in 25 L samples The kit includes a 96-well plate with capture antibodies detection antibodies calibrators diluent wash buffer read buffer and seals Sensitivity is 1 3 pg/mL with an upper quantification limit of 10 000 pg/mL
Medchemexpress LLC Leukemia inhibitory factor receptor (rat), recombinant, C-terminal His tag | >95.0% | 100 UG
Recombinant rat leukemia inhibitory factor receptor (LIFR), expressed in HEK293 cells and supplied with a C-terminal His tag. Lyophilized formulation contains PBS, trehalose, mannitol, and Tween 80, and is intended for biochemical assays, receptor-ligand studies, and cell signaling research. Purity is greater than 95% by reducing SDS-PAGE and molecular weight is approximately 116 kDa.
- Expressed in HEK293 cells to provide mammalian post-translational modifications.
- Includes a C-terminal His tag to facilitate purification and detection.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Lyophilized from PBS with stabilizers for improved shelf life.
- Recommended reconstitution at or above 100 μg/mL in water.
- Available in small research sizes for assay development and characterization.
- Store frozen and aliquot at -20°C or -80°C for extended storage.
Medchemexpress LLC CD5 Human HEK293 1mg
The CD5 protein is a potential receptor that regulates T cell proliferation Its interactions with CD72/LYB-2 and PTPN6/SHP-1 indicate multifaceted roles in cellular processes serving as key mediators of T cell responses CD5 Protein Human (HEK293 His) is the recombinant human-derived CD5 protein expressed by HEK293 with C-His labeled tag
Cell Signaling Technology PathScanR RP NDRG1 Sandwich ELISA Kit 1 Kit
PathScanR RP NDRG1 Sandwich ELISA Kit 1 Kit
Genscript Corporation PDGF R beta/CD140bBiotin Hi
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains The PDGF-AA PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities Where as PDGF R alpha binds all three PDGF isoforms with high affinity PDGF R beta binds PDGF-BB only with high-affinity PDGF R plays an essential role in blood vessel development by promoting proliferation migration and recruitment of pericytes and smooth muscle cells to endothelial cells Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites
Medchemexpress LLC Activin RIB/ALK-4 protein, mouse (HEK293, Fc) | >80.0% | 10 UG
Recombinant mouse Activin RIB/ALK-4 extracellular domain produced in HEK293 cells with a C-terminal Fc tag. Supplied lyophilized for research applications requiring the receptor ectodomain and binding or signaling studies.
- Size: 10 μg supplied lyophilized.
- Species: mouse extracellular domain.
- Expression system: HEK293 mammalian cells.
- Tag: C-terminal Fc for detection and purification.
- Amino acid range: L32-E126 (95 amino acids).
- Molecular weight: 39-50 kDa.
- Purity: >80% as determined by reducing SDS-PAGE.
- Formulation: lyophilized from PBS, pH 7.4.
- Storage: store at -20°C; aliquot and freeze at -20°C or -80°C for extended storage.
Medchemexpress LLC KRT18 Human HEK293 5ug
Recombinant human keratin 18 (KRT18) expressed in HEK293 cells and supplied with an N-terminal 10xHis affinity tag. The protein is purified to >90% by reducing SDS-PAGE, has an approximate molecular weight of 50.8 kDa corresponding to residues S2-H430, and is provided in multiple small unit sizes suitable for biochemical assays, antibody validation, and protein-protein interaction studies.
- Recombinant human keratin 18 expressed in HEK293 cells.
- N-terminal 10xHis tag for affinity purification and detection.
- Purity greater than 90% as determined by reducing SDS-PAGE.
- Approximate molecular weight 50.8 kDa (S2-H430).
- Available in small unit sizes for assay development and controls.
- Suitable for biochemical assays, antibody validation, and interaction studies.
STEMCELL Technologies Human Recombinant PDGF-CC, Size: 50 µg
Use platelet-derived growth factor (PDGF) CC in stimulating coronary artery smooth muscle cell proliferation (Gilbertson et al. J Biol Chem, 2001) and tumorigenesis (Zwerner & May. Oncogene, 2001). The PDGF family has five heparin-binding members that assemble into four homodimers (PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD) and one heterodimer (PDGF-AB) (Fretto et al. J Biol Chem, 1993; Li & Eriksson. Cytokine Growth Factor Rev, 2003) and signals through the receptor tyrosine kinases PDGFRα and PDGFRβ. PDGF is a potent mitogen for cells of mesenchymal origin and induces migration through signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al. Growth Factors, 2007). PDGF-CC is secreted as a latent growth factor and requires activation by proteolytic processing (Li & Eriksson). Human recombinant PDGF-CC from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 1 ng/mL; endotoxin levels verified ≤ 0.2 EU/μg protein. Alternative names: PDGF, Platelet-derived growth factor.
Medchemexpress LLC MMP-9 Human HEK293 50ug
MMP-9 is an important member of the MMP protein family and regulates the extracellular matrix during physiological processes such as development and tissue remodeling It involves arthritis and metastasis MMP-9 Protein Human (HEK293) is the recombinant human-derived MMP-9 protein expressed by HEK293 with tag free
Medchemexpress LLC G-CSF Human HEK293 5ug
G-CSF a pivotal cytokine regulates hematopoiesis by controlling the production differentiation and function of granulocytes and monocytes-macrophages This monomeric protein specifically promotes granulocyte development playing a crucial role in immune system regulation and blood cell formation G-CSF Protein Human (HEK293) is the recombinant human-derived G-CSF protein expressed by HEK293 with tag free
Medchemexpress LLC EGF Mouse 10ug
EGF Protein, Mouse is a recombinant epidermal growth factor supplied as a lyophilized, tag-free powder for research applications. It promotes proliferation of epidermal and other epithelial tissues, is produced in E. coli, and has an approximate molecular weight of 6-7 kDa with >95% purity. The product is provided as a 10 μg vial, should be stored frozen at -20°C, and can be aliquoted and frozen at -20°C or -80°C after reconstitution for extended storage.
- Stimulates epidermal and epithelial cell proliferation.
- Recombinant, tag free protein produced in E. coli.
- High purity (>95%) suitable for biochemical assays.
- Supplied as lyophilized powder for extended shelf life.
- Provides 10 μg per vial for small-scale experiments.
- Stable when stored frozen and after reconstitution if aliquoted.
Medchemexpress LLC MICB Human HEK293 50ug
MICB Protein a heavily glycosylated ligand for NKG2D receptor triggers cytolytic response in immune cells It resembles MHC class I molecules but lacks association with beta-2-microglobulin or peptide binding Alternative splicing leads to multiple transcript variants MICB is widely expressed especially in lymph nodes and bone marrow highlighting its immune response role in diverse physiological contexts MICB Protein Human (HEK293 His) is the recombinant human-derived MICB protein expressed by HEK293 with C-His C-6 His labeled tag
Biotium Growth Hormone (Pituitary Marker) (GH/1450), CF568 conjugate, 0.1mg/mL
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors
Medchemexpress LLC FGF-9 Human HEK293 50ug
Activin AB protein is a member of the transforming growth factor- (TGF- ) superfamily and plays a key role in various biological processes such as cell differentiation proliferation and apoptosis It is involved in embryonic development tissue repair and immune regulation FGF-9 Protein Human (HEK293 N-hFc) is the recombinant human-derived FGF-9 protein expressed by HEK293 with N-hFc labeled tag