Growth Factor Products
Medchemexpress LLC FGF basic/bFGF Huma 100ug
FGF-2 is a member of the fibroblast family involved in bone healing cartilage repair bone repair and nerve regeneration FGF-2 is also a mitotic promoter that accelerates cell proliferation FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway For example FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage respectively[1] FGF-2 is also a known carcinogen in GBM which contributes to glioma growth and vascularization[2] FGF basic/bFGF Protein Human (145a a) consists of 145 amino acids produced by E coli with tag free
Medchemexpress LLC IGF-I R Human His 100ug
IGF-I receptor (IGF1R) mediates insulin-like growth factor effects binding strongly to IGF1 Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways influencing cell survival protein synthesis and proliferation IGF1R also signals through JAK/STAT inhibiting JNK activation Hybrid receptors show variable binding to IGF1 and insulin IGF-I R Protein Human (His) is the recombinant human-derived IGF-I R protein expressed by E coli with N-6 His labeled tag
Sigma Aldrich Fine Chemicals Biosciences Human Epidermal Keratinocy
Epidermal keratinocytes comprise 90 % of all cells found in the epidermis the outermost layer of skin. They produce keratin the intermediate filament largely responsible for skins barrier function. Through their interactions with epidermal melanocytes keratinocytes obtain melanin and store it as a means of protection from UV radiation.HEK provide an excellent model system to study many aspects of epithelial function and disease particularly those related to skin biology and toxicology as well as HPV infection. When grown on inserts and provided with the liquid/air interface HEK can differentiate into a stratified squamous epithelium and serve as a more physiological 3D tissue model for in vitro studies.
American Research Products Inc Anti FGF2 bFGF HuGAL F2
Anti-Human FGF2/bFGF (HuGAL-F2) Research Grade
Medchemexpress LLC FGF basic/bFGF Huma 10ug
FGF-2 is a member of the fibroblast family involved in bone healing cartilage repair bone repair and nerve regeneration FGF-2 is also a mitotic promoter that accelerates cell proliferation FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway For example FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage respectively[1] FGF-2 is also a known carcinogen in GBM which contributes to glioma growth and vascularization[2] FGF basic/bFGF Protein Human (145a a His) consists of 145 amino acids produced by E coli with tag free
Sigma Aldrich Fine Chemicals Biosciences Human Epidermal Keratinocy
Epidermal keratinocytes comprise 90 % of all cells found in the epidermis the outermost layer of skin. They produce keratin the intermediate filament largely responsible for skins barrier function. Through their interactions with epidermal melanocytes keratinocytes obtain melanin and store it as a means of protection from UV radiation.HEK provide an excellent model system to study many aspects of epithelial function and disease particularly those related to skin biology and toxicology as well as HPV infection. When grown on inserts and provided with the liquid/air interface HEK can differentiate into a stratified squamous epithelium and serve as a more physiological 3D tissue model for in vitro studies.
Medchemexpress LLC IGF-I R protein, human (HEK293, C-His tag) | >95.0% | 10 UG
IGF-I receptor protein (human) is a recombinant, HEK293-expressed extracellular domain supplied as a filtered PBS solution for research applications involving IGF signaling, binding, and pathway studies.
- Recombinant human IGF-I receptor expressed in HEK293 cells.
- C-terminal His tag for detection and purification.
- Amino acid range E31-N932 representing the extracellular domain.
- Purity ≥95.0% by reducing SDS-PAGE.
- Supplied as 0.22 μm filtered PBS, pH 7.4.
- Store at -80°C; avoid repeated freeze-thaw cycles.