Growth Factor Products
Sigma Aldrich Fine Chemicals Biosciences Heregulin beta 1 human An
Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1 NRG2 NRG3 and NRG4). HRG1-1 (heregulin-1 also referred to as NRG1-1) contains an Ig (immunoglobulin) domain and an EGf (epidermal growth factor)-like domain that is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. The gene HRG1-1 is mapped to human chromosome 8p12. Recombinant human Heregulin-1 is a 7.5 kDa polypeptide consisting of only the EGf domain of heregulin-1 (65 amino acid residues).
Cell Signaling Technology IGF-I Receptor beta D4O6W Rabbit mAb BSA and Azide Free 100 ug
IGF-I Receptor beta D4O6W Rabbit mAb BSA and Azide Free 100 ug
Cell Signaling Technology PathScanR RP Phospho-IGF-I Receptor beta Tyr1131 Sandwich ELISA Kit 20 Kit
PathScanR RP Phospho-IGF-I Receptor beta Tyr1131 Sandwich ELISA Kit 20 Kit
Revvity Health Sciences Inc AlphaLISA SureFire Ultra Human & Mouse Phospho-c-Jun (Ser63) Detection Kit, Control Lysate
AlphaLISA SureFire Ultra Human & Mouse Phospho-c-Jun (Ser63) Detection Kit, Control Lysate
Genscript Corporation IGF-I Porcine
Insulin-like growth factor 1 (IGF-1) is a hormone similar in molecular structure to insulin but has a much higher growth-promoting activity IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges IGF-1 may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts It is able to stimulate glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake It may also play a role in synapse maturation
REPLIGEN CORPORATION LONGR3 IGF-I Freeze Dried Powder, 200X More Potent Than Insulin, Animal-Free Manufacturing, 1 mg
The LONGR3 IGF-I Freeze Dried Powder is a highly potent, animal-free growth factor that enhances mammalian cell culture performance. It boosts cell density and viability while improving volumetric productivity by up to 62% over unsupplemented cultures. Distinct from traditional insulin, it specifically activates the type I IGF Receptor, ensuring superior signaling for cell proliferation. This product's enhanced stability and compatibility with various cell types make it an excellent choice for chemically-defined culture applications.
Sigma Aldrich Fine Chemicals Biosciences Human Epidermal Melanocyte
Epidermal melanocytes are pigment-producing cells located at the basal level of epidermis where they interact with keratinocytes via cellular processes called dendrites. Melanin the pigment produced by melanocytes and responsible for skin color is then transferred to keratinocytes where it is stored in vesicles called melanosomes located around the nucleus to provide protection from UV radiation. HEM maintain their characteristic shape in culture for many generations. They produce melanin and serve as a useful cell model for the studies of melanocyte proliferation and differentiation as well as progression of melanocytic neoplasia.
Sigma Aldrich Fine Chemicals Biosciences Human Epidermal Keratinocy
Epidermal keratinocytes comprise 90 % of all cells found in the epidermis the outermost layer of skin. They produce keratin the intermediate filament largely responsible for skins barrier function. Through their interactions with epidermal melanocytes keratinocytes obtain melanin and store it as a means of protection from UV radiation.HEK provide an excellent model system to study many aspects of epithelial function and disease particularly those related to skin biology and toxicology as well as HPV infection. When grown on inserts and provided with the liquid/air interface HEK can differentiate into a stratified squamous epithelium and serve as a more physiological 3D tissue model for in vitro studies.
Revvity Health Sciences Inc AlphaLISA SureFire Ultra Human & Mouse Total CDK8 Detection Kit, 500 Assay Points
AlphaLISA SureFire Ultra Human & Mouse Total CDK8 Detection Kit, 500 Assay Points
Cell Signaling Technology PhosphoIGFI Receptor beta Insulin Receptor beta Tyr1146 Rabbit mAb BSA and Azide Free 100 ug
PhosphoIGFI Receptor beta Insulin Receptor beta Tyr1146 Rabbit mAb BSA and Azide Free 100 ug