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IGF-I receptor protein (human) is a recombinant, HEK293-expressed extracellular domain supplied as a filtered PBS solution for research applications involving IGF signaling, binding, and pathway studies.
Recombinant human IGF-I receptor expressed in HEK293 cells.
C-terminal His tag for detection and purification.
Amino acid range E31-N932 representing the extracellular domain.
Purity ≥95.0% by reducing SDS-PAGE.
Supplied as 0.22 μm filtered PBS, pH 7.4.
Store at -80°C; avoid repeated freeze-thaw cycles.
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Epidermal keratinocytes comprise 90 % of all cells found in the epidermis the outermost layer of skin. They produce keratin the intermediate filament largely responsible for skins barrier function. Through their interactions with epidermal melanocytes keratinocytes obtain melanin and store it as a means of protection from UV radiation.HEK provide an excellent model system to study many aspects of epithelial function and disease particularly those related to skin biology and toxicology as well as HPV infection. When grown on inserts and provided with the liquid/air interface HEK can differentiate into a stratified squamous epithelium and serve as a more physiological 3D tissue model for in vitro studies.
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FGF-2 is a member of the fibroblast family involved in bone healing cartilage repair bone repair and nerve regeneration FGF-2 is also a mitotic promoter that accelerates cell proliferation FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway For example FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage respectively[1] FGF-2 is also a known carcinogen in GBM which contributes to glioma growth and vascularization[2] FGF basic/bFGF Protein Human (145a a His) consists of 145 amino acids produced by E coli with tag free
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
FGF-2 is a member of the fibroblast family involved in bone healing cartilage repair bone repair and nerve regeneration FGF-2 is also a mitotic promoter that accelerates cell proliferation FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway For example FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage respectively[1] FGF-2 is also a known carcinogen in GBM which contributes to glioma growth and vascularization[2] FGF basic/bFGF Protein Human (145a a His) consists of 145 amino acids produced by E coli with tag free
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
The Meso Scale Discovery R-PLEX Human IGF-1 Assay is a multiplex immunoassay panel that allows simultaneous quantitative measurement of Insulin-like Growth Factor 1 (IGF-1) in human serum plasma and cell culture supernatants This assay utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and rapid results The assay requires 50 L or less sample volume and can be read on MSD instrument platforms The R-PLEX IGF-1 assay delivers precise and reproducible results for human IGF-1 quantification
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
FGF-2 is a member of the fibroblast family involved in bone healing cartilage repair bone repair and nerve regeneration FGF-2 is also a mitotic promoter that accelerates cell proliferation FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway For example FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage respectively[1] FGF-2 is also a known carcinogen in GBM which contributes to glioma growth and vascularization[2] FGF basic/bFGF Protein Human (145a a) consists of 145 amino acids produced by E coli with tag free
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More