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NERVE GROWTH FACT MOUSE 100UG
Fibroblast Growth Supplement 5 ml
Greater than 95% by SDS-PAGE analysis. Stemfactor bFGF is shipped at room temperature. Lyophilized bFGF is stable for up to 6 months from date of receipt when stored at −20 °C to −80 °C. Reconstituted bFGF, at concentrations greater than or equal to 0.1 mg/mL, is stable for up to 3 months when stored at −20 °C and up to 6 months when stored at −80 °C.
Purified Mouse Nerve Growth Factor 2.5s
designed to support the growth of keratinocytes. BulletKit also available which is comprised of basal media and a SingleQuots Kit of growth factors and supplements.
Recombinant Transforming Growth Factor Beta TGFb1 1mg
Epidermal growth factor (EGF) is characterized by high affinity binding to various EGF receptors (EGFRs) and the production of mitogenic responses (Carpenter & Cohen). EGF promotes EGFR dimerization, resulting in activation of downstream pathways including PI3K, ERK1/2, JAK/STAT, β-catenin, and calcium signaling. EGF is secreted by the gut-associated salivary and Brunner’s glands, is found in a variety of body fluids, and stimulates cell proliferation and differentiation in rodent and neonatal human intestine (Wright et al.). Central nervous system stem cells also proliferate in response to the EGF stimulus (Reynolds & Weiss).
Recombinant Pig VEGF-A
FGM Fibroblast Growth Medium 500mL Basal Medium (contains no growth factors cytokines or supplements) Sterility: Neg pH: 7.4-7.7 Osmolality: 297-313 mOsm/kg Developed to support the growth or primary human fibroblasts. FGM is serum-free
InVitria’s Optiferrin recombinant human transferrin is completely animal- and blood-free. Its functional performance in cell culture is equivalent to human holo-transferrin in terms of reversible iron binding, transferrin-receptor binding, and promoting cell growth and productivity. It is compatible with a variety of cell types and applications including stem, primary, bioproduction cells, proliferation of human HSC, and Sp2/0 hybridoma cells. Optiferrin offers significant regulatory advantages due to its safety and consistency.Made in the USA.
TGF beta 1 Recombinant Protein (Active)
Basic fibroblast growth factor (bFGF) is a prototypic member of the fibroblast growth factor family. Cytokines in the FGF family possess broad mitogenic and cell survival activities (Folkman & Klagsbrun; Kimelman & Kirschner) and are involved in a variety of biological processes including cell proliferation, differentiation, survival, and apoptosis (Folkman & Klagsbrun; Klagsbrun; Rifkin & Moscatelli). bFGF has the β-trefoil structure (Ponting & Russell), binds to the four FGF receptor (FGFR) family members, and activates JAK/STAT, PI3K, ERK1/2, and other receptor tyrosine kinase (RTK) signaling pathways. It supports the maintenance of undifferentiated human embryonic stem cells (Xu et al.; Kang et al.), stimulates human embryonic stem cells to form neural rosettes (Zhang et al.), and improves proliferation of human mesenchymal stem cells and enhances chondrogenic differentiation (Solchaga et al.).
Use stem cell factor (SCF) to promote cell survival, proliferation, differentiation, adhesion, and functional activation of cells at multiple levels of the hematopoietic hierarchy. SCF is an early-acting cytokine that activates PI3K, JAK/STAT, and MAPK pathways upon binding to its receptor. Together with other cytokines like thrombopoietin and Flt3/Flk-2 Ligand, SCF is used to promote expansion of primitive hematopoietic stem cells and multipotent progenitor cells in culture (Martin et al. Cell, 1990; Kent et al. Clin Cancer Res, 2008.). In combination with various growth factors and erythropoietin, SCF increases proliferation and differentiation of myeloid and erythroid progenitor cells and a subset of lymphoid progenitor cells (Broudy VC. Blood, 1997). Human recombinant SCF from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 15 ng/mL; endotoxin levels verified ≤ 1 EU/μg protein. Alternative names: Kit ligand, Mast cell growth factor, Steel factor, Stem cell factor.
Epidermal growth factor (EGF) is characterized by high affinity binding to various EGF receptors (EGFRs) and the production of mitogenic responses (Carpenter & Cohen). EGF promotes EGFR dimerization, resulting in activation of downstream pathways including PI3K, ERK1/2, JAK/STAT, β-catenin, and calcium signaling. EGF is secreted by the gut-associated salivary and Brunner’s glands, is found in a variety of body fluids, and stimulates cell proliferation and differentiation in rodent and neonatal human intestine (Wright et al.). Central nervous system stem cells also proliferate in response to the EGF stimulus (Reynolds & Weiss).
Akron’s Human Serum Albumin (HSA) 25% Solution is manufactured, tested, and released following relevant cGMP guidelines for blood-derived ancillary materials and supported by a Type II Master File (MF) on file with the FDA which can be referenced during your drug or biologic application process. Akron’s HSA 25% Solution is specifically formulated for cell and gene therapy commercial manufacturing.