Cell Lines and Cell Cultures
Eurofins Discoverx ChemiScreen Ghrelin Receptor Membrane Preparation, 1 vial. (HTS187M)
The ChemiScreen Ghrelin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of GHSR surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen GPR68/OGR1 Proton-Sensing Receptor Stable Cell Line, 2 vials. (HTS153C)
The ChemiScreen GPR68/OGR1 Proton-Sensing Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of pH based activation of GPR68 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GPR68 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of GPR68, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx PathHunter CHO-K1 SSTR5 β-Arrestin Cell Line, 2 vials. (93-0402C2)
The PathHunter SSTR5 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. somatostatin) based activation of SSTR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR5 and EA-tagged β-Arrestin-2. Activation of SSTR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC A-431-Luc2; Epidermoid Carcinoma; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.
American Research Products Inc AntiHuman CD47
Anti-Human CD47 [B6H12] In Vivo Antibody - Low Endotoxin is a in vivo antibody with human reactivity produced in mouse Available in 100 mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
ATCC Quantitative Genomic DNA from; Micrococcus luteus; Strain: 130.21
Genomic DNA isolated from a preparation of Micrococcus luteus strain 130.21 (ATCC 10240). This product can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
Eurofins Discoverx ChemiBrite CXCR3 Chemokine Receptor Stable Cell Line, 2 vials. (HTS003L)
The ChemiBrite CXCR3 Chemokine Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of CXCR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CXCR3 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of CXCR3, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx PathHunter CHO-K1 mC5AR1 β-Arrestin Cell Line, 2 vials. (93-0577C2)
The PathHunter mC5AR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. apelin-13) based activation of mC5AR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mC5AR1 and EA-tagged β-Arrestin-2. Activation of mC5AR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
World Precision Instrument AutoLCI Adapter for 60mm Dish, Dual
With EVOM™ AutoLCI, cells cultured in different vessel types can be imaged. Interchangeable vessel adapters can accommodate various vessel types including well-plate, culture flask, and culture dish. The system includes a well-plate adapter, but you can buy separately different adapters for a variety of vessels used.
Eurofins Discoverx PathHunter CHO-K1 CXCR2 (IL8RB) β-Arrestin Cell Line, 2 vials. (93-0202C2)
The PathHunter CXCR2 (IL8RB) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL8/IL8) based activation of CXCR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR2 and EA-tagged β-Arrestin-2. Activation of CXCR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section - Alzheimer's Disease: Brain: Cerebellum, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC J1;Mouse ES
For-profit Organizations: For every order of this item, you must work directly with the contributor, Whitehead Institute to (i) negotiate a research-use license, and/or (ii) have the contributor provide authorization to ATCC to ship this item under your existing license. We cannot ship this item until we receive communication directly from Whitehead Institute that we are authorized to ship each order. We are providing the following contact information, but this information may change without notice: Whitehead Institute for Biomedical Research Attn. Shoji Takahashi Phone: (617) 258-8930 Email: takahashi@wi.mit.edu. Once ATCC has received authorization from Whitehead Institute, your order will be reviewed, and this item will be released for shipment if all requirements are met. If you need assistance with your order, please contact our Customer Care team.
Lonza Walkersville Human CD34+ Progenitor Cells from Mobilized Peripheral Blood, Positive Selection, 1 Million
Mobilized peripheral blood CD34+ hematopoietic stem and progenitor cells are positively selected using a immunomagnetic CD34 microbead labeling system. Cells are cryopreserved in Lonza Cryo Media in a cryovial. Cell purity is determined post thaw using a FACS assay. Count and viability is determined using AO/PI. Cells are collected from healthy donors following IRB protocols.Manufactured by AllCellsBenefits:Obtain large quantities of CD34+ from a donorCertificate of analysis (CoA) provided for each lot purchasedTest negative for mycoplasma, bacteria, yeast, and fungiHIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lotsApplications:CAR-T therapy developmentiPSC generationAutoimmune diseaseImmunologyCancer researchContent:1 x Cryopreserved ampule of Human CD34+ Progenitor Cells from Mobilized Peripheral Blood containing ≥ 1 million cells
Electron Microscopy Sciences Rodent Brain Matrix Adult Ferret, Coronal
RBM allow the investigator to slice either coronal (perpendicular to center line) or sagittal (parallel to center line) sections through the brain at intervals as small as 1mm. All RBM's are identical and durable to insure reproducible sections in the day-to-day, year-to-year, or on a between laboratory basis.
Constructed from high grade zinc to allow for rapid temperature equilibration, easy cleaning, and sterilization. The matrices are designed to accommodate the brains of rodents placed ventral side up. The channels are precisely cut at 1 mm intervals and 0.3 mm wide.
Type: Coronal
Promocell GmbH PromoCell HTEpC Pellet from > 1 million Normal Human Tracheal Epithelial Cells
Cell pellet consisting of 1 million cells dissolved in 200µl RNAlater for subsequent RNA, DNA or protein analysis. Note: Cell pellets cannot be revived.Our Cell Pellets are stored in RNAlater – an aqueous protection solution that rapidly permeates the cells and stabilizes cellular DNA, RNA, and proteins and protects them from degradation. This makes our Cell Pellets very useful for a wide range of research applications like gene expression analysis, cell characterization studies, and protein characterization experiments.Each Cell Pellet is made from 1 million cells and is dissolved in 200 µl RNAlater. The Cell Pellets are produced from released cell lots and have the same characteristics, i.e. expression profile or cell type specific antigens. On request, viable cells from the same lot are available for cultivation.