Cell Lines and Cell Cultures
Genscript Corporation CHO-K1/Cyno VISTA Stable Cell
V-domain Ig suppressor of T cell activation (VISTA) is a potent negative regulator of T-cell function that is expressed on hematopoietic cells VISTA levels are heightened within the tumor microenvironment in which its blockade can enhance antitumor immune responses in mice In humans blockade of the related programmed cell death 1 (PD-1) pathway has shown great potential in clinical immunotherapy trials
ATCC HCT116-SLC10A4-KO-c2; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC10A4-KO-c2 cell line contains a +1 bp insertion in SLC10A4 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
ATCC Lactobacillus rhamnosus; genomic DNA
Genomic DNA isolated from Lactobacillus rhamnosus. This bacterial strain is also available as ATCC Catalog No. 21052™.
Eurofins Discoverx ChemiScreen TRH Thyrotropin-Releasing Hormone Receptor Stable Cell Line, 2 vials. (HTS126C)
The ChemiScreen TRH Thyrotropin-Releasing Hormone Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. TRH) based activation of TRHR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TRHR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of TRHR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Quantitative Synthetic; Powassan virus; lineage II RNA
Quantitative synthetic Powassan virus lineage II RNA can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load. This preparation includes fragments from the E, NS1, NS5, and 3’ UTR regions.
ATCC HCM-CSHL-0090-C25; Cancer Model Primary; Pancreatic Ductal Adenocarcinoma; Human (Homo sapiens)
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