General Cell Lines and Cell Cultures
Amsbio LLC Inducible GFP & Luciferse Co-Expression HEK293 cell line
Inducible GFP & Luciferse Co-Expression HEK293 cell line
Eurofins Discoverx PathHunter U2OS OPRK1 β-Arrestin Cell Line, 2 vials. (93-0234C3)
The PathHunter OPRK1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dynorphin A) based activation of OPRK1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRK1 and EA-tagged β-Arrestin-2. Activation of OPRK1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter HEK 293 IκB Degradation Cell Line, 2 vials. (93-0538C1)
The PathHunter HEK 293 IκB Degradation Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting the NFκB pathway. This cell line enables detection of IκB levels, allowing for assessment of NFκB pathway activation-induced IκB degradation. This product uses EFC technology. The cell line included overexpresses IκB target protein fused to ProLabel. EA is contained in the detection reagent. Upon pathway-activation-induced degradation of IκB EFC signal is lost. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
Lonza Walkersville Mouse CD1 Brain Striatum Neuro
Ready-to-use Clonetics Mouse Brain Striatum Neurons are isolated from Mouse CD1 brain (E14 15) The cell suspensions of high quality primary embryonic brain neuronal cells (including glia) are prepared by standardized methods and are ready for immediate culture Each vial of striatum cells contains approximately 4 million viable cells This will seed into 6 or more wells of a 24-well plate and 30 or more wells of a 96-well plate using the recommended plating densities and medium After approximately 4 days in culture the cells will form a neurite network and by the 7th day debris will be minimal Recommended Media PNGM BulletKit (CC-4461)
Lonza Walkersville Mouse CD-1 Hepatocytes Cryo
Cryopreserved CD-1 mouse hepatocytes suspension format specifically pre-tested for metabolic activity of general Phase I and Phase II metabolism in suspension This product is not suitable for applications requiring adherent cells
Eurofins Discoverx ChemiScreen C3aR Anaphylotoxin Receptor Membrane Preparation, 1 vial. (HTS016M)
The ChemiScreen C3aR Anaphylotoxin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of C3AR1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx PathHunter U2OS HTR2C β-Arrestin Cell Line, 2 vials. (93-0289C3)
The PathHunter HTR2C cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin) based activation of HTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2C and EA-tagged β-Arrestin-2. Activation of HTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 GPR31 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0406C2)
The PathHunter GPR31 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR31 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR31 and EA-tagged β-Arrestin-2. Activation of GPR31 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Brain: Vermis Cerebelli, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Paraffin Tissue Section - hypertension: Heart Ventricle, right, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Paraffin Tissue Section - Human Parotid Tumor: Pleomorphic Adenoma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Abcam Piribedil dihydrochloride, D2/D3 dopamine receptor agonist, 10MG
MW 371.27 g/mol, Purity >99%. D₂/D₃ dopamine receptor agonist. D₃ selectivity demonstrated in vitro. Improves attentional dysfunction in combination with L-DOPA.
The product is subject to the following: Abcam Restricted Use Statement
Cell Systems Corporation 5 Vials Primary Bovine Aortic Endothelial Cells (Pooled) - Same Lot (CSC2B2V5)
Boost your research program with 5 identical vials of passage 3 Primary Bovine Aortic Endothelial Cells (Pooled) while saving ~ 20% on purchase. Isolated from eight individual donor veal calf descending aortae without positive control antibody labels. Each vial contains ~1 x 10^6 cells with 85-92% viability under ideal conditions. They are available at Passage 3 (<12 cumulative population doublings) and will initiate a Passage 4 cell culture in a 75 cm2 flask. Each vial of cells is shipped with Bac-Off (antibiotic) and CultureBoost (animal derived growth factors) at no additional cost. You can enhance consistency in your research program with reserved lots. Need vials in bulk? Contact your Fisher Scientific Sales representative for tailored quotes. Tight Deadline? Our cells are available for next day delivery after the purchase order is received. Accelerate Your Research! Try our Attachment Factor (4Z0-201, 4Z0-210) – innovative 5 seconds plating solution for all surfaces.
Eurofins Discoverx cAMP Hunter CHO-K1 mTAAR1 Gs Cell Line, 2 vials. (95-0177C2)
The cAMP Hunter mTAAR1 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. p-tyramine) based activation of mTAAR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type mTAAR1, a naturally Gs coupled GPCR. Upon activation of mTAAR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section - Human Prostate Tumor, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.