General Cell Lines and Cell Cultures
ATCC Merck Pneumococcal polysaccharide powder Type 2 (d2) 200mg
Purified pneumococcal polysaccharides are manufactured by Merck & Company for small quantity distribution by ATCC. The pneumococcal powders include those types which are components of the current 23-valent vaccine against Streptococcus pneumoniae.Each of the polysaccharide antigens used in the polyvalent vaccine is extracted and purified separately. These vaccine products can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
Cayman Chemical ApelIn-12humnmouserat5mg
An endogenous agonist of the APJ receptor; induces calcium mobilization in APJ-Gαq16 cells expressing human APJ (EC50 = 0.18 nM); inhibits HIV-1 and HIV-2 infection in NP-2/CD4/APJ cells (mean IC50 = 63 UG/ml); inhibits or stimulates the expression of genes associated with apoptosis, mitosis, and DNA repair in IEC-6 and Caco-2 cells, respectively, at 0.01 µM; induces the production of NO in HUVECs from 100-1,000 nM; increases gastric acid secretion, as well as stomach histamine synthesis and secretion in rats from 20-100 UG/kg; reduces MAP in rats at 15 UG/kg
Biochain Institute Inc Paraffin Tissue Section - Human Bone Tumor: Chondrosarcoma, Grade I - II, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Bioss KD-Validated Insulin receptor
Insulin Receptor Primary Antibody Unconjugated Public Immunogen Range 910-976/1382 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
ATCC S9.6; Hybridoma; Mouse (Mus musculus)
The mAb product of this cell line may be used for microarray detection without amplification of RNA; detection of R-loops. Immunogen: DNA-RNA hybrids synthesized from φΧ174 single stranded-DNA. Primary reactivity: DNA-RNA hybrids
Cell Applications Inc Proliferating Rat Brain Microvascular Endothelial Cells (RBMVEC), Adult
Proliferating Rat Brain Microvascular Endothelial Cells (RBMVEC), Adult
ATCC Paenibacillus validus
Paenibacillus validus strain Q1 is a whole-genome sequenced bacterium that was isolated from soil in Spain. This product can be used as a quality control strain.
Eurofins Discoverx ChemiScreen M3 Muscarinic Acetylcholine Receptor Stable Cell Line, 2 vials. (HTS116C)
The ChemiScreen M3 Muscarinic Acetylcholine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. acetylcholine) based activation of CHRM3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CHRM3 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CHRM3, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx KILR EL4 Cell Pool, 2 vials. (97-1019P033)
The KILR EL4 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of EL4 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
Eurofins Discoverx PathHunter U2OS GPR119 β-Arrestin Cell Line, 2 vials. (93-0356C3)
The PathHunter GPR119 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. OEA) based activation of GPR119 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR119 and EA-tagged β-Arrestin-2. Activation of GPR119 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section - Multiple Sclerosis Disease: Brain: Pons, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Salmonella enterica; subspecies enterica; serovar Typhimurium; Strain: SAP18-6199
Salmonella enterica subsp. enterica serovar Typhimurium strain SAP18-6199 was isolated from a human. This whole-genome sequenced bacterium was part of the 2018 PulseNet-GenomeTrakr joint proficiency test exercise. This strain has applications in enteric disease research, infectious disease research, and zoonotic disease research.
American Research Products Inc Human TLR8 ELISA Kit
This Human Toll Like Receptor 8 (TLR8) ELISA Kit is a precoated Sandwich ELISA assay designed to detect and quantify the target analyte in serum plasma tissue homogenates and other biological fluids This product is for Research Use Only
ATCC Quantitative Genomic RNA from; Human rhinovirus 1B; Strain: B632
Quantitative Genomic RNA from Human rhinovirus 1B strain B632 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load.