General Cell Lines and Cell Cultures
ATCC Purified; Influenza B virus; B/Florida/4/2006
Purified Influenza B virus strain B/Florida/4/2006 is propagated in SPF chicken embryonated eggs. The virus was isolated from a human patient in 2006 and was deposited by the Florida Department of Health and purified by sucrose gradient centrifugation. It has applications in respiratory disease research, in vitro infectivity assays, antiviral studies, spiking studies, and a variety of other research.
ATCC Human adenovirus 26; Strain: BP-2
Human adenovirus 26 strain BP-2 is propagated in A549 cells (ATCC CCL-185). This strain was derived from ATCC VR-1104, which was originally isolated from an anal specimen from a 9-month-old male child in Washington, DC. This product has applications in respiratory and infectious disease research.
ATCC U-2 OS-Luc2; Osteosarcoma; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.
Eurofins Discoverx ChemiScreen MC3 Melanocortin Receptor Membrane Preparation, 1 vial. (HTS022M)
The ChemiScreen MC3 Melanocortin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of MC3R surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx Ready-to-Assay FP Prostanoid Receptor Frozen Cells, 2 Vials of Cells. (HTS093RTA)
The Ready-to-Assay FP Prostanoid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. prostaglandin F2a) based activation of PTGFR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGFR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of PTGFR, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen D3 Dopamine Receptor Membrane Preparation, 1 vial. (HTS103M)
The ChemiScreen D3 Dopamine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of DRD3 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen EP3 Prostanoid Receptor Membrane Preparation, 1 vial. (HTS092M)
The ChemiScreen EP3 Prostanoid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of PTGER3 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx Ready-to-Assay D1 Dopamine Receptor Frozen Cells, 2 Vials of Cells. (HTS102RTA)
The Ready-to-Assay D1 Dopamine Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. dopamine) based activation of DRD1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD1 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of DRD1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx Ready-to-Assay EP1 Prostanoid Receptor Frozen Cells, 2 Vials of Cells. (HTS099LRTA)
The Ready-to-Assay EP1 Prostanoid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. prostaglandin E2) based activation of PTGER1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGER1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of PTGER1, the resulting calcium activity can be assayed in either detection mode. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PrecisION hKv7.4/hKv7.5 Recombinant Stable Cell Line, 2 vials. (CYL3096)
The PrecisION hKv7.4/hKv7.5 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv7.4/Kv7.5 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv7.4/Kv7.5 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC HCT116-SLC35F2-KO-c2; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC35F2-KO-c2 cell line contains a +1 bp insertion in SLC35F2 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
ATCC HCM-CSHL-0094-C25; Cancer Model Primary; Pancreatic Ductal Adenocarcinoma; Human (Homo sapiens)
A signed Material Transfer Agreement Addendum for HUB/Organoid Products is required to order this item. No further signed Addendum is required if it was previously submitted and processed in connection with a prior order. We cannot ship this item unless the signed Addendum is in place. To submit the signed Addendum, email it to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your Addendum will be reviewed, and this item will be released for shipment if all other requirements are met. If you need assistance with your order, please contact our Customer Care team.
Eurofins Discoverx ChemiScreen GABAB Receptor Stable Cell Line, 2 vials. (HTS119C)
The ChemiScreen GABAB Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. GABA) based activation of GABBR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GABBR1 alongside partner subunit GABBR2 and endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of GABBR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.