General Cell Lines and Cell Cultures
Biochain Institute Inc Frozen Tissue Section - Depression: Brain: Parietal Lobe, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
ATCC Pfizer Pneumococcal polysaccharide powder Type 3 (d3) 200mg
Purified pneumococcal polysaccharide type 3 is manufactured by Pfizer, Inc., for small-quantity distribution by ATCC. The pneumococcal powder type 3 is a component of the current 13-valent vaccine against Streptococcus pneumoniae. The pneumococcal polysaccharide type 3 can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Montana Molecular Human Succinate Receptor (SUCNR1, SUCR1) BacMam, 30mL
Use this assay to express the human Succinate receptor in your cells of interest. BacMam packaging provides efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in primary or iPSC-derived cells. Importantly, BacMam expression is easily titrateable to suit your experimental needs. This tool can be co-expressed with Montana Molecular's assays for cAMP to investigate signaling dynamics at the SUCNR1 receptor.
Amsbio LLC TLR8/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
TLR8/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
Eurofins Discoverx PathHunter CHO-K1 GHSR1b β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0354C2A)
The PathHunter GHSR1b cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ghrelin) based activation of GHSR1b GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GHSR1b and EA-tagged β-Arrestin-2. Activation of GHSR1b stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 GPR25 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0368C2A)
The PathHunter GPR25 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR25 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR25 and EA-tagged β-Arrestin-2. Activation of GPR25 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section - Alzheimer's Disease: Brain: Medulla oblongata, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx cAMP Hunter CHO-K1 DRD4 Gi Cell Line, 2 vials. (95-0123C2)
The cAMP Hunter DRD4 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD4 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type DRD4, a naturally Gi/Go coupled GPCR. Upon activation of DRD4, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter Jurkat NFAT Pathway Reporter Cell Line, 2 vials. (93-1141C19)
The PathHunter Jurkat NFAT Pathway Reporter Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting the NFAT pathway. This cell line enables assessment of NFAT pathway stimulation based on changes in the expression of a NFAT response element-driven reporter protein. This product uses EFC technology. The included cell line expresses ProLabel-tagged reporter protein under the control of a NFAT pathway-inducible transcriptional response element. Pathway activation induces expression of the ProLabel-tagged protein, allowing detection of EFC signal upon addition of EA-containing detection reagent. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
ATCC Pfizer Pneumococcal polysaccharide powder Type 54 (d15B) 200mg
Purified pneumococcal polysaccharide type 15B is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 15B can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Eurofins Discoverx PathHunter CHO-K1 mHTR2A β-Arrestin Cell Line, 2 vials. (93-0567C2)
The PathHunter mHTR2A cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin/5-HT) based activation of mHTR2A GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mHTR2A and EA-tagged β-Arrestin-2. Activation of mHTR2A stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen CXCR6 Chemokine Receptor Membrane Preparation, 1 vial. (HTS054M)
The ChemiScreen CXCR6 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CXCR6 surface expression. ChemiScreen membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
ATCC Human adenovirus 41; Quantitative DNA
Quantitative Genomic DNA from Human adenovirus 41 strain Tak (73-3544) can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load.
Eurofins Discoverx cAMP Hunter CHO-K1 mGIPR Gs Cell Line, 2 vials. (95-0154C2)
The cAMP Hunter mGIPR Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. GIP) based activation of mGIPR GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type mGIPR, a naturally Gs coupled GPCR. Upon activation of mGIPR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Rhodopseudomonas palustris
Rhodopseudomonas palustris strain CGA009 is a chloramphenicol-resistant derivative of R. palustris strain CGA001. This whole-genome sequenced bacterium can be used in antimicrobial resistance research.