General Cell Lines and Cell Cultures
Discovery Life Sciences Melanoma Active Tx PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
IPHASE PHARMA SERVICES LLC Plateable ICR/CD-1 Mouse Hepatocytes,Male,5million
Primary Hepatocytes are isolated from human and animal liver tissues. It's a tool for cytochrome P450 induction, Hepatotoxicity assays and siRNA devlivery, Transfection, Sandwitch model, 3D Primary Hepatocyte Spheroid Model (Three-Dimensional Liver Culture system) and organoids culture. IPHASE provides both suspension and plateable Hepatocytes, animal or human and speical species includes: cat(feline), Guinea pig, BALB/c Nude, Ferret, Gerbil customize hepatocytes. Plateable Hepatocytes need to be used in conjunction with Thaw medium, Plateable medium, Maintenance medium and Collagen Coated Plate.These products require shipment in LN2 container therefore customer need to return the container.
Discovery Life Sciences CRC Active Tx PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Eurofins Discoverx cAMP Hunter CHO-K1 ADRB2 Gs Cell Line, 2 vials. (95-0121C2)
The cAMP Hunter ADRB2 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. isoproterenol) based activation of ADRB2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADRB2, a naturally Gs coupled GPCR. Upon activation of ADRB2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Amsbio LLC NFAT Leeporter™ Luciferase Reporter-HEK293 Cell Line
NFAT Leeporter™ Luciferase Reporter-HEK293 Cell Line
Eurofins Discoverx PathHunter CHO-K1 SCTR β-Arrestin Cell Line, 2 vials. (93-0237C2)
The PathHunter SCTR cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. secretin) based activation of SCTR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SCTR and EA-tagged β-Arrestin-2. Activation of SCTR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ABclonal Technology CASR Rabbit pAb
The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia.
Amsbio LLC IL-8 Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
IL-8 Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Eurofins Discoverx PathHunter CHO-K1 GPR6 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0634C2)
The PathHunter GPR6 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR6 and EA-tagged β-Arrestin-2. Activation of GPR6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Montana Molecular Human CALCRL Big Sky BacMam, 15mL
Human Calcitonin Receptor-like (CALCRL), also called Calcitonin Receptor-like Receptor (CRLR). Big Sky BacMam packaging provides efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in primary or iPSC-derived cells. BacMam expression is easily titrateable to suit your experimental needs.
Eurofins Discoverx PathHunter CHO-K1 rDRD2L (Long Isoform) β-Arrestin Cell Line, 2 vials. (93-0785C2)
The PathHunter rDRD2L cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of rDRD2L GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rDRD2L and EA-tagged β-Arrestin-2. Activation of rDRD2L stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 mCNR1 (CB1) β-Arrestin Cell Line, 2 vials. (93-0471C2)
The PathHunter mCNR1 (CB1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CP 55,940) based activation of mCNR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCNR1 and EA-tagged β-Arrestin-2. Activation of mCNR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.