General Cell Lines and Cell Cultures
Cell Biologics Luciferase-Expressing Rat Primary Colonic Microvascular Endothelial Cells
Luciferase-Expressing Rat Primary Colonic Microvascular Endothelial Cells
Cell Biologics RFP-Expressing Rat Primary Colonic Microvascular Endothelial Cells
RFP-Expressing Rat Primary Colonic Microvascular Endothelial Cells
Cell Biologics Cas9-Expressing Rat Primary Proximal Tubular Epithelial Cells
Cas9-Expressing Rat Primary Proximal Tubular Epithelial Cells
Cell Biologics Luciferase-Expressing Monkey Primary Aortic Fibroblasts
Luciferase-Expressing Monkey Primary Aortic Fibroblasts
Cell Biologics BKS db Control Mouse Colonic Smooth Muscle Cells
BKS db Control Mouse Colonic Smooth Muscle Cells
Cell Biologics Cas9-Expressing Monkey Primary Vein Endothelial Cells
Cas9-Expressing Monkey Primary Vein Endothelial Cells
Cell Biologics GFP-Expressing Monkey Primary Colonic Smooth Muscle Cells
GFP-Expressing Monkey Primary Colonic Smooth Muscle Cells
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Rectum, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter CHO-K1 FPR1 β-Arrestin Cell Line, 2 vials. (93-0314C2)
The PathHunter FPR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. formylpeptides) based activation of FPR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged FPR1 and EA-tagged β-Arrestin-2. Activation of FPR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC CHO-ICAM-1 Ovary, transfected; Chinese hamster (Cricetulus griseus)
CHO-ICAM-1 is a cell line exhibiting epithelial morphology that was isolated from the ovary of a female patient. This cell line was deposited by BL Pasloske.
Eurofins Discoverx PathHunter CHO-K1 mCMKLR1 β-Arrestin Cell Line, 2 vials. (93-0537C2)
The PathHunter mCMKLR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. chemerin) based activation of mCMKLR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCMKLR1 and EA-tagged β-Arrestin-2. Activation of mCMKLR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Amsbio LLC Luciferase (firefly) Expression Hela cells (Puro)
Luciferase (firefly) Expression Hela cells (Puro)
Eurofins Discoverx ChemiScreen GAL2 Galanin Receptor Stable Cell Line, 2 vials. (HTS186C)
The ChemiScreen GAL2 Galanin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. galanin) based activation of GALR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GALR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of GALR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Genscript Corporation CHO-K1/EP2/G15 Stable Cell Li
Prostaglandin (PG) E2 exerts its actions by acting on a group of G-protein-coupled receptors (GPCRs) There are four GPCRs responding to PGE2 designated subtypes EP1 EP2 EP3 and EP4 and multiple splicing isoforms of the subtype EP3 The EP subtypes exhibit differences in signal transduction tissue localization and expression regulation Studies have identified that EP2 mediates many processes such as facilitating ovulation and fertilization suppressing dendritic cell differentiation and promoting amyloid- formation in Alzheimer s disease
Eurofins Discoverx U2OS GPR39 Gq Cell Line, 2 vials. (95-1015C3)
The GPR39 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. Zn2+) based activation of GPR39 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GPR39, a naturally Gq coupled GPCR. Upon activation of GPR39, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.