General Cell Lines and Cell Cultures
ATCC Chlamydia trachomatis; Strain: LGV I; DNA
Quantitative Genomic DNA from Chlamydia trachomatis LGV Serovar I strain 440 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC Primary Small Airway Epithelial; Cells, Fibrosis;Human (Homo sapiens)
Primary small airway epithelial cells were isolated from the respiratory tract of a donor with fibrosis. The cells have an application in microbial (eg, viral, bacterial) infection and pathogenesis, airway inflammation and wound healing, asthma, pulmonary fibrosis, chronic obstructive pulmonary disease, chronic bronchitis, toxicology, and testing of pharmaceuticals.
Biochain Institute Inc Frozen Tissue Section - Liver Cirrhosis: Prostate, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Frozen Tissue Section - Bronchitis: Lung, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx ChemiScreen D5 Dopamine Receptor Membrane Preparation, 1 vial. (HTS129M)
The ChemiScreen D5 Dopamine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of DRD5 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
STEMCELL Technologies Human Peripheral Blood CD4+CD25+CD127lowFOXP3+ T cells (Tregs), Frozen , Size: 1 x 10^6 cells
Primary human CD4+CD25+CD127lowFOXP3+ T cells were isolated from peripheral blood using immunomagnetic separation techniques. These cells are often referred to as regulatory T cells and are used in immune response assays. Cells were obtained using Institutional Review Board (IRB)-approved consent forms and protocols.
Eurofins Discoverx PathHunter CHO-K1 mGHSR1a β-Arrestin Cell Line, 2 vials. (93-0605C2)
The PathHunter mGHSR1a cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. grehlin) based activation of mGHSR1a GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGHSR1a and EA-tagged β-Arrestin-2. Activation of mGHSR1a stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 CX3CR1 β-Arrestin Cell Line, 2 vials. (93-0956C2)
The PathHunter CX3CR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CX3CL1/fractalkine) based activation of CX3CR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CX3CR1 and EA-tagged β-Arrestin-2. Activation of CX3CR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen SST1 Somatostatin Receptor Membrane Preparation, 1 vial. (HTS170M)
The ChemiScreen SST1 Somatostatin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of SSTR1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx PathHunter CHO-K1 PTHR2 β-Arrestin Cell Line, 2 vials. (93-0306C2)
The PathHunter PTHR2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PTH) based activation of PTHR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTHR2 and EA-tagged β-Arrestin-2. Activation of PTHR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
BPS Bioscience Inc CD40 - HEK293 Cell Line, 2 vials, Recombinant HEK293 cell line
Recombinant HEK293 cell line expressing full length human CD40 (Tumor necrosis factor receptor superfamily member 5; TNFRSF5), Genbank Accession No. NP_001241.1. Expression is confirmed by real-time qPCR and Western blot.Included with the purchase of these cells is a 10-year license to use the cells and their progeny in your immediate laboratory, for research use only.
ATCC Human adenovirus 6; Strain: Tonsil 99
Human adenovirus 6 strain Tonsil 99 is propagated in HeLa cells (ATCC CCL-2). This strain was isolated from the tonsil tissue of a 7-year-old girl with chronically infected and enlarged tonsils in Washington, DC. The strain has applications in respiratory disease research.
STEMCELL Technologies Human Peripheral Blood CD4+CD25- T cells (Responders), Frozen, Size: 2 x 10^6 cells
Primary human CD4+CD25- T cells were isolated from peripheral blood using immunomagnetic separation techniques. CD4+CD25- T cells are often refered to as responder T cells.Cells were obtained using Institutional Review Board (IRB)-approved consent forms and protocols.