Innovative Grade US Origin Rabbit Plasma K2 EDTA 500ml - Innovative Grade US Origin Rabbit Plasma from Innovative Research is manufactured using whole blood collections. The animals used for this material are of US Origin, ensuring that only the highest-quality material is used for the production of the plasma.
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An ionizable cationic lipid (pKa 6.39) has been used in the generation of LNPs for siRNA delivery in vitro and in vivo LNPs containing O12-D3-I3 and encapsulating ferrocene and siRNA targeting Nrf2 or system xc- cystine/glutamate transporter decrease viability of HepG2 cells LNPs containing O12-D3-I3 and an mRNA reporter selectively accumulate in the tumor and liver over the lungs kidneys spleen and heart in mice LNPs containing O12-D3-I3 and encapsulating ferrocene and siRNA targeting Nrf2 or system xc- cystine/glutamate transporter reduce tumor growth and volume in an MCF-7 breast cancer mouse xenograft model LNPs containing O12-D3-I3 and encapsulating siRNA targeting Factor VII decrease hepatocyte Factor VII mRNA levels in mice
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MW 425.9 Da, Purity >99%. Peripheral D₂-like receptor antagonist. Does not readily cross the blood-brain barrier, and displays gastrokinetic and antiemetic properties.